Basic Information

Insect: Anopheles coluzzii
Gene Symbol: -
Assembly: GCA_016097175.1
Location: CM027926.1:3091059-3096266[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.012 0.61 10.3 2.4 6 23 251 268 251 268 0.99

2 12 0.11 5.6 7.3 0.2 1 23 274 297 274 297 0.88

3 12 3.2e-05 0.0017 18.4 0.7 1 23 305 327 305 327 0.95

4 12 0.00021 0.011 15.8 1.5 2 23 336 357 335 358 0.93

5 12 1.7e-05 0.00091 19.2 0.8 1 19 467 485 467 490 0.94

6 12 0.00021 0.011 15.8 0.9 1 23 498 520 498 520 0.95

7 12 0.024 1.2 9.4 2.6 3 23 530 551 528 551 0.96

8 12 0.0006 0.031 14.4 0.2 2 23 558 579 557 579 0.96

9 12 2.4 1.3e+02 3.0 7.1 1 23 589 612 589 612 0.96

10 12 0.0017 0.087 13.0 1.9 2 23 619 640 618 641 0.94

11 12 0.00018 0.0095 16.0 0.5 1 23 647 669 647 669 0.97

12 12 0.025 1.3 9.3 1.4 1 23 675 698 675 698 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.012	0.61	10.3	2.4	6	23	251	268	251	268	0.99
2	12	0.11	5.6	7.3	0.2	1	23	274	297	274	297	0.88
3	12	3.2e-05	0.0017	18.4	0.7	1	23	305	327	305	327	0.95
4	12	0.00021	0.011	15.8	1.5	2	23	336	357	335	358	0.93
5	12	1.7e-05	0.00091	19.2	0.8	1	19	467	485	467	490	0.94
6	12	0.00021	0.011	15.8	0.9	1	23	498	520	498	520	0.95
7	12	0.024	1.2	9.4	2.6	3	23	530	551	528	551	0.96
8	12	0.0006	0.031	14.4	0.2	2	23	558	579	557	579	0.96
9	12	2.4	1.3e+02	3.0	7.1	1	23	589	612	589	612	0.96
10	12	0.0017	0.087	13.0	1.9	2	23	619	640	618	641	0.94
11	12	0.00018	0.0095	16.0	0.5	1	23	647	669	647	669	0.97
12	12	0.025	1.3	9.3	1.4	1	23	675	698	675	698	0.91

Sequence Information

Coding Sequence: ATGGACATCGGAAGAGTGGATCCTGAGCCGGTTAGCTGCGATCAATGCCTGCTGTGTCAGTTAAACAGTACCGATCGAAATTTGGTAACCGAGCGGCTCGACTCCGGCCAAGGCACCGTAGCGGATGTTATCTGTAAACATTTTTGGCTTTCGGCAGCGACATGCACAGGCCGATACATCTGCACCACCTGCTGGGATGTGACGTATTCGTTTCACAAATTCTATCTCGAAGTGGAACGGTTGCATTCACCACTAGATCCAGCCGCGGTTAAGCAAGAGCCACCAGCTGCACCAACCCAAACAAAGCAGCAAGCGGACACAACGAAAGCCGACCAGCTCGTCTGGCTGAACGAGGGCAGCACGCTCATCACGAACGTGAACGAAGTTTTCGTGAAGGAGAGCTTACCAGAAAGCGACGATGAACCGGCCGAAGAGGACGAAGATTCCGACGAGGATGCAAACATTCCTTTGGCAACGCTCAAGCAGGCAGCGAAACCGCCCGCCACGAAAACGCTCGTACCTCTGCAGCAGGATGACGACGGCACGGCAGGAAACGCTCCATTCCCCGGGGTAGGTTTGTCCTTGTGCCGCATTAGCGGCAGTTCGCTGGAGCTGCTTTGCCACGATTGCTACCGGAAGTCGAACAATGCGAACAGCGGCGAGCGAAGCAAGGAGGGAGCGCGCTTTACCTTTGCCGCACTGCTGAAACACTACCGGCAGGTACACGGCAAGCCGGGGTACGCGGTGTGCTGCAATCGAAAGTACACGCGGCGACGGTCGCTCAAGATGCACCTGCAGACGCACGGCCGGAAGTTGGTGTACCGGTGCGTGCCGTGCGGCATCAAGTTCCGCAAGCAGGAGTCGCTGGACGAGCACAACCTGCTGATCCACACGTCGGAGGAGGAGAAGCGGTACCGGTGCGACAAGTGCGACAAAGCGTTCGCCACGGAGCATCTGCTCAACTCGCACGGCCTGTGGCATGAGAATGTGGCCAGAAAGAACATCACCTGCAGCGTGTGCAACATTTTCTTCACCAGCCAACCGTCGCTGAAAAAGCATCGCGCACTGCACCACCCTTCGATGGAGAGCAGCGATGTGAGCGTACCCTCCACCAACGGCAGCACTGCAGAGGCGGTCGACGATGAAAAATTAGTCGCCTCGCAGTATCGCACCCGCATTTCGGCCACGGAAATCGGCGAACAGGAGAAGCTGATCCGGCGCCACTGTCTGCTGCACTGCAGCCGGTGCGCCTTCTTCGGCGAAAGCTTCACCCAGCTCAAGGAGCACGCGGCCGAGGCGCACGGGCTGCGCAGCTGCGACGTCGTGTGCTGCGAGCGCACGTACAGCAAGCGGCAGTCGCTGTACGAGCACTGTCTGGTGCACGAGAATCCCGACTGCTTCCGGTGCGACGTGTGCGGCAAGAGCTACTCCAGCAGCCGGAGCCTGCAAAACCACAAGTGGCGCATACACACGCCCGCGGCCGAGCGCCCGTTTCGCTGCGACGTCTGCGGCGAAACGTTCGTGAAGGATTATCTGCTCAAGCAGCATCTCGTGCATCATTTGGCGAAGCACAAAAAGCTAAACCACTGCGACGTGTGCGAGCGTTCGTTCACGACCGCGACGGTGCTCAAGTGCCACCAGCAGACGTACCATGGCGGCGGCTTCGCCCTGATCTGTGATATCTGCGCGAAGGGTTTCAACAGCCGGGCGTTGTTCGAAAACCATCGCCTGACGCACTCGGTCGAAGGCAAGTCGCAGCTGAAGCATCAGTGCGAACAGTGCAAGAAATGGTTGCGCAACAAGAAATCCTACCAGCAGCATCGCATCCGCTGCCACACGAACGACGGTCCGGTGACGTGCAAGTTCTGCGGCAAGGAGTCGGTGAACGCGAGCGCCCTCAAGTCGCACGTGCATCTGCATCACGCGGCCCGGCCCGAATACCCCTGCACGCTGTGCGACAAACGGTTCAAGACGGCACTGCGGTTGCGGGAGCACGAGGCGACGCACACGGGCACGGCACTGTACCGGTGTCCCTGGTGTCCGCGCACGTTCGCCTGCGGCTCGAACATGTACAAGCACAAAAAGGCGGGTCACCCGCTCGAGTGGGCTGCCTCGGTGAAGCAACGGTTCGGCGAGCGATGA
Protein Sequence: MDIGRVDPEPVSCDQCLLCQLNSTDRNLVTERLDSGQGTVADVICKHFWLSAATCTGRYICTTCWDVTYSFHKFYLEVERLHSPLDPAAVKQEPPAAPTQTKQQADTTKADQLVWLNEGSTLITNVNEVFVKESLPESDDEPAEEDEDSDEDANIPLATLKQAAKPPATKTLVPLQQDDDGTAGNAPFPGVGLSLCRISGSSLELLCHDCYRKSNNANSGERSKEGARFTFAALLKHYRQVHGKPGYAVCCNRKYTRRRSLKMHLQTHGRKLVYRCVPCGIKFRKQESLDEHNLLIHTSEEEKRYRCDKCDKAFATEHLLNSHGLWHENVARKNITCSVCNIFFTSQPSLKKHRALHHPSMESSDVSVPSTNGSTAEAVDDEKLVASQYRTRISATEIGEQEKLIRRHCLLHCSRCAFFGESFTQLKEHAAEAHGLRSCDVVCCERTYSKRQSLYEHCLVHENPDCFRCDVCGKSYSSSRSLQNHKWRIHTPAAERPFRCDVCGETFVKDYLLKQHLVHHLAKHKKLNHCDVCERSFTTATVLKCHQQTYHGGGFALICDICAKGFNSRALFENHRLTHSVEGKSQLKHQCEQCKKWLRNKKSYQQHRIRCHTNDGPVTCKFCGKESVNASALKSHVHLHHAARPEYPCTLCDKRFKTALRLREHEATHTGTALYRCPWCPRTFACGSNMYKHKKAGHPLEWAASVKQRFGER

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00101234;
90% Identity: iTF_00104669;
80% Identity: -