Basic Information

Insect: Anopheles christyi
Gene Symbol: ABTB2
Assembly: GCA_000349165.1
Location: KB702460:6309-13100[+]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 2 1.3e-19 2.8e-17 62.1 0.0 6 104 1678 1778 1675 1784 0.88

2 2 1.2 2.8e+02 1.0 0.1 80 109 1786 1815 1775 1816 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	2	1.3e-19	2.8e-17	62.1	0.0	6	104	1678	1778	1675	1784	0.88
2	2	1.2	2.8e+02	1.0	0.1	80	109	1786	1815	1775	1816	0.86

Sequence Information

Coding Sequence: ATGATCTGTACGGACGACTGCACCTGCAGCCTGTGCAGGGAGCTGCGTGGGTATAAGCTGAAAGTGAAACCAAACAAAGACGCTGGTCGCGCACCGTACGCCGATGCCGGAAGTCAGCAGCAGTCCAAGTATTGCAAAAACGCCAAACTAACGCGCAATGATAACTTCATACTGAGGCGTCGAACCTCCAACGATTACCCGTCCCGTTCGCCAGACGGACGGCAAGCATCGCTAAGCGTACTACCGACAGGTGATGACAATCCATACGATTGCCAATTACAGCAGCAACAAAACCACAACCAGGGCCAGGGTGGCCATCGGGATGCCCGGTACGCCCCGAACCAGAGCAGCACTCGGATGAAGAAGGCCCAAAGCTACAACGAAATACCGAGCGTGGGTAATGGGGGCGGACGGCCACGCTATCACCCAGCCGCCCTCAGCTCGAAAATGATCAAGAGCACCAACAACCTAACAGAGGAGGACGATTACTACAGCTATCTGCCACCGTCACCACCGCCCCCGGTGCCGGCCAGTGGTGGCCCCACAGTGAAAAACAAAATCGAGAAGCAGAAAGATCACAAAGTGATCATCTACTTCGGTGACTCGATCGCGCACAGGAAAAGCGACAAGACACGTCCCGCGCCACCGCCACCGACCGGTACACCACCACCGCCAAAGACCGCCGAACTGAACGTGTTTCACGCCCAACGACTATGCGAGGAAACGGCCGAAATGCTGCAGCAACGTGAGGTAGTTGGTGGTAGTAGCAGCAGTTGTACCGGTAGTAGCAGCAATGGCGCTTCAAGTCGACCGACCGTACGCGAAGCGCTAGAAAAGAAACCCGATCCGCCCGGTGCTAAACCGGGCAAGGAGTTTATGCTACAGCTTAAGTCCGTGCTGGAGGAAAAGAATCGTGGTGTGCCGAGTGAAACGCCCCAAGGGGTAACAGTACCGATTGGACCGGAAGTGGAAAGCGTTGGCAGTGCGGCGTGTCAGGAAACGAAGCCAAAGCGGGCGCACACACAGGTGGTGGAGATACGGCGCGTCGATAAGACGGTGGCAACGGTCGATGGGGTAACGGACACGTCGCTACCATCGTTCGTCGAGAGCGTCATTAACGGTGTGATCAACATCAAGATCGAGGAAAGCTTCAAGGTCGCGTCGGATATTGTGCAGGCCGTGTTTGAGGATGCGGGCCCGGACGGTGGAGCGGTCGAGTATGGCTACGATGTGGACGATGTGGGCGATCCATTCGATTGGAGCTTCGTGCAGAACTGGAGAGCACGACCTTCCGGTACGGCTGTTGCGAATGGGCAGGTAAGCTCACCGCCCAACACGTCCAGCAATCAGAGCAGCAGCCTCGGTCTCGCCAACAATCCCACGCACAATGGTTCCAGTGCCGTCGGCGGAGTCGGTCCTGGTAGCAGCAGTGCCAGCAATTACCCGGCCAGTCCCAATGGACTATCGCCCGGGAACCATTACATAGCGTCCTCTAATCCAGTCTCCTCACCAGGGGCTCGAATACAAAGCCCGGCCGTCGCAACACCAGCCCCGCGTGTATCGAAAGAGATCGCACTAAGACCCACCAATGGGAATGGTGATATGCGTAACTATAGCCTATCACCAGTCAACCAACAGTCTGCAGGagggcaacagcaaagcagtgaaccgaacgacaacggtagaaagtatcacgcgctgccggcacagcagcaatcggctggacagcagcaacacgcgcaacagcatccattagccggggtgcatcatcagcaccattcccagcagcagcagcagcagcagcagcagcaacatccacaacatcagcagcaacagcaacaacaacagcagcatcatcaacaaTCTGGCCCTCACCGATCGGTGGCAGGACCGACGAAGCTTACCGTGCAAAGCTCCCCAGTAAAAGCCCAACCGGCAATGGTAAGTGCCGGGCTGGACAAATCCCCAGTTGGTTCCAATGTCTCCAGCCACCCATCCAGCAACGACCAGAACAACAGCAAGCGAACGGTCAATGGTAACGTGATCAGCAGCGTTACCACACTGAACGAGCAGCTGAACGGAGGTAGCAACAGTTGCACCAGCAGTGGCAGCAGCGTTAGCCACCTCAAGCAACACTTTTCCCAGAGTCATCACGCCGTGCCGACCTCGTATCATCATCAGGTGGCATCGTCGGCGGGTGCCAGTTCCGGTCAGCCTGGTACGCATCTTGCCAGCCCCGTTACAAAGGGTGCACCGTTGGGCATTACCCGAACGCACCATCACACCGGGACGCACGATTTTCGTGGCCTGCAGCGCGTGAACGAGTGTCACAGCTCGTCGGACGAGAATCGATCGTCTGGGCACGCGAGCATGTCGGATACGGGGCATGGCAGTAGCTCACCGGGCGGTGGTACGCGTGCCGGTGGTCCACTTGGACCACTGCCCGAGGATCGGCTGGCTGCTGGCGTTACCAATCGGAGTGCGCGGTCGCGGGCTAGCTCGAACCATTCGCGCTCCCGGCACCGGGCAACACCGGCCAAAATCCCATGGGGTGGCGGCGGACTGGAAGACATTAAGATGGCCATCCAGCAGCTAACGATGCGTTCGCACACGTCCACCTCAACGTACAGCAGTCTGAGCGCGGGCTCGGAAAGTTCGGAACCAGTACGTCGGCTCGGGCGTTACAGTTCGCTCGAAACGGTCAACACGAACGTGACCAGTGCGGACGAGTTCGTGTGGGTTGACTCACACAACCGGCTGGTGGAGCTGCAGCATCCGCCCTGGAGCCAGCACTGTGTGCTACGCGTCATCCGTACCGGGCGCTGCCGGGAGTACGCCGAGCGAGTATCGGTCGAAGCGGTACCGCGGCTTGGATACTTGTTGCAGCGCGCACTGGTAAGGGTGGCCCGAGAAGTGCAGCGACTGTCGGGGTGTTTGGGCCTTTGCTCCAAACACGAGGTGGCCGGTGCGTTCAAGATCGTACTATCACCCGCTCTATCCGATTCCTGCATCAAGGCGTGTTTACGTGCGGCGGCCATGTTTGCGGTACCGGGCGACAGTGCATTGAAGCAGAGCAAGTCGGCACGGGCAGGATTGCAGCTACCGGTGGGACGCTTTCACCGCTGGATGGCCGATGCACGGCTCGGTCGGTTTGTGCACGAGTATGCGGCGGTGTACCTGTGCGCCGGGTTGGAGAATCTGCTGGAGGAGATCTTTCTTCAGTGCCTACCGACGGATCCGGGTGCAGCGCTTACTGCGACGGGTTTGGAGCATGCAATTGCCGGGTCGGGTGATCTGTGGGGTTTGCTGCAGCCGTACGCCCATCTAAATGCGGGCCGTGTTGCATCGGGTGCGCTTACGATGCCTCGCTGGGCAAGCCAATCATCCATCAACTCGGGCGGTGGTACGAGCGCACTCGAACCCTGTCTGCTGACCACGTGCGTTGGAAGTTTGAACGAGCTGAAGGATCTGGTTGGGCGGGCGCAGCAACGCAGCCAACATATACCCATTTCGCAGACCGCGTTCCGGGTGCTGTTTTACTTTATGCGCTGCTCCCAGCTCGAGCATAATGATGTGGGAGCGGCCACGAACGGTGCGGTCAATAACATTCAGGAACTGTGCTACGAGCGGGCGTATGTTGTACTGCCCCCGCTAGTCGAATGGCTGCGGGTATCTTCTGCTCATGCCGAGTATCGGCACGCGCTGTTGATCGATAAGGACGATATAATGCAGGCGGCGCGATTGCTGCTCCCGGGTGTTGACTGTCCACCGCGACTAATTGCGTCCGAGGAGGAGCTGCCGGCCAAGCGGACGGGCCTGTCCGGTACGCAATCGATCAGCTCGTCTAACCATTCCGGGCAAACGCAACCACTGCACGGTTCACTCACCTCCAACTCGTCGATATCGACGACGGGAAGCATTGAGGACTCAAGCGAATGTGGACGGCGTGCGACCTACGCGTTAGCCTTCCGTCTAATGCTGACCGGCCGACCGGAACTGCTCATACAGGCACTGTCGCTAGTACCGCCAACGACGCGGTACGATACGCTAAACCATCAGGGCCTGACGGCGCTCATGATAGCGGCGGTGCGCAATGATGAAACCACACTGCAAACACTGCTCGATGCTGGAGCCGATCCAAACATCGAGGTACCTGCCTCCGGACATCCGAACTGTCCGGCCATCCATCCGGAAACGCAACACTGGACCGCAGTTACGTTCGCTGCCTGCAAGGGCAACTATCAGGCACTACGCATACTGCTCGATCGGGGCGCACACGTCGAGGGTGGCGCACGGCTCAGCGAAGACAAGTGTACGCTCACGCCGCTACAGGTAGCGAGCGGATCGGGCATTGTGGAGGTGGTGGCACTGCTGCTTGCCCACGGTGCGCACGCATTTCTCTCGACCCAGCAGAAGGATCTGCTGTGCTTCTCGGGAACGGCCCAGCGTGGTTGCTACAGCGCTATCTCGGTATCAGCCGCCCACGGTCAGCGTGTAACGCTGAGGAAGCTCCTGTCACATCCACTAGCTCCGGGCAGCAGGGAGGTACTGTCACTTGAGGAGATGCTTGCGGAGGGCGACGGTGGCAATACGCGCACCCAGCTCGACCGTCAGCCGGAGGCACCACCGACACTGAACAAAACCCAAATCAAAAGTCTTCAAGAGGCCATGTATCATAGTGCTGAAAATAATCATTTAGATATTACCATCGAGCTGCGAGCGCTTGGCGTACCATGGACATTGCACTGCTGGATGCACGCCCTCGCCGCCGCCCACGAGCTGCGCCTGGATGCCGTCATCGATCAGCTGCTGCAAGACTTTCTGCAAGTTTGTCCCGATGACTACAGTCAGCAGTTTGTGACCGAGTGTCTGCCGCTGTTGTTTAACATTTTCCGCTACAGCAAGAAGGAAGGCACCACACTGCTATTGGCCGACATCTTCAGCACCTGTTTCGGCTGGGAACCGATCAAACCGATCAAGGAGCCGGTCCTGCAGCCCTCGAACGGATCGCGCATCGATCCCAAGTTCGTCAACAATCCCGAACTGAGCGATGTCACATTCCGAGTGGAAAATCGTATCTTTTACGGGCACAAAATCGTTCTCGTCACCGCATCTCCGCGTCTGCAGAGTATGTTGAGCTCGAAGCTGAACGAAGGCACCGGCACACCGACCGTGCAGATCAACGATATTCGGTATCATATATTCGAGTTGGTAATGCAATTCCTGTACAGCGGAGGATGCAGCGCCCTGGATGTGGCAGCTGGGGATGTGCTGGAGTTGATGGCAGCGGCCAGCTTCTTCCAGCTGGAAGGGCTTTTGCGCTACACGGAAGCGCGCTGTGCCGAGATGATCGACATCGACAATGTGGTCGCCATGTACATACATGCCAAGGTCTACAATGCCCAGAAGCTGATGGAATTTTGCCAGGGTTTCCTGTTGCAAAACATGGTCGCATTGCTAACGTACGACGACTCGGTGAAGCGGCTGCTATTTGCAAAGAAAATCCCGAACCATGATGTGCTGACCGGTTTGCTGACCACACTCCAGGCCCGCATTAAGGCGCGCCGTAACAGCGCGGCCGCATCCAGTGCGGGAGGTGGCAACGGTGCACCGGTGAACGGTGGTGGTCCTACTACACCCACTGCACCACCACCGGCGAATCGCTCGTCAGCTAATGGAAAGTCCTCTAAGTAA
Protein Sequence: MICTDDCTCSLCRELRGYKLKVKPNKDAGRAPYADAGSQQQSKYCKNAKLTRNDNFILRRRTSNDYPSRSPDGRQASLSVLPTGDDNPYDCQLQQQQNHNQGQGGHRDARYAPNQSSTRMKKAQSYNEIPSVGNGGGRPRYHPAALSSKMIKSTNNLTEEDDYYSYLPPSPPPPVPASGGPTVKNKIEKQKDHKVIIYFGDSIAHRKSDKTRPAPPPPTGTPPPPKTAELNVFHAQRLCEETAEMLQQREVVGGSSSSCTGSSSNGASSRPTVREALEKKPDPPGAKPGKEFMLQLKSVLEEKNRGVPSETPQGVTVPIGPEVESVGSAACQETKPKRAHTQVVEIRRVDKTVATVDGVTDTSLPSFVESVINGVINIKIEESFKVASDIVQAVFEDAGPDGGAVEYGYDVDDVGDPFDWSFVQNWRARPSGTAVANGQVSSPPNTSSNQSSSLGLANNPTHNGSSAVGGVGPGSSSASNYPASPNGLSPGNHYIASSNPVSSPGARIQSPAVATPAPRVSKEIALRPTNGNGDMRNYSLSPVNQQSAGGQQQSSEPNDNGRKYHALPAQQQSAGQQQHAQQHPLAGVHHQHHSQQQQQQQQQQHPQHQQQQQQQQQHHQQSGPHRSVAGPTKLTVQSSPVKAQPAMVSAGLDKSPVGSNVSSHPSSNDQNNSKRTVNGNVISSVTTLNEQLNGGSNSCTSSGSSVSHLKQHFSQSHHAVPTSYHHQVASSAGASSGQPGTHLASPVTKGAPLGITRTHHHTGTHDFRGLQRVNECHSSSDENRSSGHASMSDTGHGSSSPGGGTRAGGPLGPLPEDRLAAGVTNRSARSRASSNHSRSRHRATPAKIPWGGGGLEDIKMAIQQLTMRSHTSTSTYSSLSAGSESSEPVRRLGRYSSLETVNTNVTSADEFVWVDSHNRLVELQHPPWSQHCVLRVIRTGRCREYAERVSVEAVPRLGYLLQRALVRVAREVQRLSGCLGLCSKHEVAGAFKIVLSPALSDSCIKACLRAAAMFAVPGDSALKQSKSARAGLQLPVGRFHRWMADARLGRFVHEYAAVYLCAGLENLLEEIFLQCLPTDPGAALTATGLEHAIAGSGDLWGLLQPYAHLNAGRVASGALTMPRWASQSSINSGGGTSALEPCLLTTCVGSLNELKDLVGRAQQRSQHIPISQTAFRVLFYFMRCSQLEHNDVGAATNGAVNNIQELCYERAYVVLPPLVEWLRVSSAHAEYRHALLIDKDDIMQAARLLLPGVDCPPRLIASEEELPAKRTGLSGTQSISSSNHSGQTQPLHGSLTSNSSISTTGSIEDSSECGRRATYALAFRLMLTGRPELLIQALSLVPPTTRYDTLNHQGLTALMIAAVRNDETTLQTLLDAGADPNIEVPASGHPNCPAIHPETQHWTAVTFAACKGNYQALRILLDRGAHVEGGARLSEDKCTLTPLQVASGSGIVEVVALLLAHGAHAFLSTQQKDLLCFSGTAQRGCYSAISVSAAHGQRVTLRKLLSHPLAPGSREVLSLEEMLAEGDGGNTRTQLDRQPEAPPTLNKTQIKSLQEAMYHSAENNHLDITIELRALGVPWTLHCWMHALAAAHELRLDAVIDQLLQDFLQVCPDDYSQQFVTECLPLLFNIFRYSKKEGTTLLLADIFSTCFGWEPIKPIKEPVLQPSNGSRIDPKFVNNPELSDVTFRVENRIFYGHKIVLVTASPRLQSMLSSKLNEGTGTPTVQINDIRYHIFELVMQFLYSGGCSALDVAAGDVLELMAAASFFQLEGLLRYTEARCAEMIDIDNVVAMYIHAKVYNAQKLMEFCQGFLLQNMVALLTYDDSVKRLLFAKKIPNHDVLTGLLTTLQARIKARRNSAAASSAGGGNGAPVNGGGPTTPTAPPPANRSSANGKSSK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00109254; iTF_00096492; iTF_00103784; iTF_00100411; iTF_00097884; iTF_00105930; iTF_00101067; iTF_00099767; iTF_00093565; iTF_00095747; iTF_00104491; iTF_00107091;
90% Identity: iTF_00093565;
80% Identity: -