Basic Information

Insect: Anopheles bellator
Gene Symbol: Zfa
Assembly: GCA_943735745.2
Location: OX030928.2:71812560-71815548[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.77 45 4.5 0.8 2 23 221 243 220 243 0.94

2 17 0.0032 0.18 12.0 0.1 2 21 253 272 252 273 0.94

3 17 0.91 52 4.3 1.2 1 21 280 300 280 301 0.93

4 17 0.047 2.7 8.3 3.8 2 23 418 440 418 440 0.96

5 17 3.5 2e+02 2.4 0.0 2 20 454 472 453 474 0.92

6 17 0.18 10 6.5 1.4 1 20 481 500 481 502 0.94

7 17 0.0035 0.2 11.9 1.4 2 23 580 602 580 602 0.94

8 17 0.065 3.7 7.9 0.1 1 20 617 636 617 638 0.94

9 17 0.011 0.65 10.3 2.3 1 21 651 671 651 672 0.96

10 17 2.5 1.4e+02 2.9 5.3 2 23 728 751 726 751 0.84

11 17 2.9 1.7e+02 2.7 0.4 2 20 768 786 767 787 0.91

12 17 7.9e-05 0.0046 17.1 0.4 1 23 795 818 795 818 0.96

13 17 7.6e-05 0.0044 17.1 0.6 1 23 825 847 825 847 0.97

14 17 0.0013 0.076 13.2 0.3 1 23 853 876 853 876 0.95

15 17 7.9e-06 0.00045 20.2 0.3 1 23 882 904 882 904 0.98

16 17 0.029 1.7 9.0 3.4 3 23 912 933 910 933 0.95

17 17 0.00017 0.0096 16.0 1.0 1 23 939 961 939 961 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.77	45	4.5	0.8	2	23	221	243	220	243	0.94
2	17	0.0032	0.18	12.0	0.1	2	21	253	272	252	273	0.94
3	17	0.91	52	4.3	1.2	1	21	280	300	280	301	0.93
4	17	0.047	2.7	8.3	3.8	2	23	418	440	418	440	0.96
5	17	3.5	2e+02	2.4	0.0	2	20	454	472	453	474	0.92
6	17	0.18	10	6.5	1.4	1	20	481	500	481	502	0.94
7	17	0.0035	0.2	11.9	1.4	2	23	580	602	580	602	0.94
8	17	0.065	3.7	7.9	0.1	1	20	617	636	617	638	0.94
9	17	0.011	0.65	10.3	2.3	1	21	651	671	651	672	0.96
10	17	2.5	1.4e+02	2.9	5.3	2	23	728	751	726	751	0.84
11	17	2.9	1.7e+02	2.7	0.4	2	20	768	786	767	787	0.91
12	17	7.9e-05	0.0046	17.1	0.4	1	23	795	818	795	818	0.96
13	17	7.6e-05	0.0044	17.1	0.6	1	23	825	847	825	847	0.97
14	17	0.0013	0.076	13.2	0.3	1	23	853	876	853	876	0.95
15	17	7.9e-06	0.00045	20.2	0.3	1	23	882	904	882	904	0.98
16	17	0.029	1.7	9.0	3.4	3	23	912	933	910	933	0.95
17	17	0.00017	0.0096	16.0	1.0	1	23	939	961	939	961	0.98

Sequence Information

Coding Sequence: ATGCGAAGAACTTCGAAACGGAGGAAGATCGTATCGAAGCGAGAAGAACCTGCAGCATCCGCACGAATATGCAGCATCTGCACGAAGGAGGCGTCCGAAGAAACGACGCTTGCACTATCCGCGGTTGTTGACGACGGAAATCGTAACACTGTGGGGAGCATTATCGAAGAAATAGCGTCGGTCAAGATCAAGCACACCGAACAGTGCATCTGCGCGTCATGTTGGAAGCGGGTGCTGGAAGCGCACGAATTGCGGAGCGCAATACGCAGCTCGAAAATTTTCGGTGAAGCCAGTGAGGAACCCCCCGCCGAGTGCCCGGTGATGATCCAGCCATGCCCGGAGGAGGACGGCAAAGTGTACGAGGAATACGAGTATTTAATGGAATACCTCGAAAACTGCGGATCGAACGATCACACCTACAACGATCGAGATGCAGAGGACGATGTCTCCACAGTGGGCGAATACTATGTTAAAGATGAAGACCAAGCTGAAGAACGGTCGTCGTTCcttttggaaacagccattaTGGCCGATACCAAACCTAACGACGATGAAAATCGATCCGCGAATATTACACGACAGTTCGAAATGCCGGACCCGGCGCTTATCGTGCACGACGAGCTGCATGAGCGGCACCGACGAGTGGAGGTGGCCGGGGTGCGATGCTGTGGCTGCAGTTTCGTAGCGCCCAACCGCAAAAGTCTGATGCAGCACTCGGAAACGGTGCACGCGATCAACATTGTCGACATTGGCGATTACTGTCCGATCTGTTTCTTCAAGTTCGCCACTGACAAGCAGCTGGAGCGGCACATACAAGAGTTCAAGTCGAACAACATGTACGTTTGTTTGCGGTGCAATCGATTCTACAACATGCGCCGGCGTCTGTACAATCACCTGCTAAGGTGCTGTGACGAAGAGCTCGGTGGTGCCGCGGACGGTGAGGACTCGCCAGATGagaacgaggacgacgaggagcaGGAAAATGACGAACTCGACGATGAGGCTGAGGTGTATGGCGAAGAAGTCCCAGGCGAGTACGACACAATCGAGTACCTTCTGCAGCAGGACGACGCACCGCTTCGTGGAATCGATCGCCGACGGATGCACCGTTACCGGGCTCAATTTGCCAAAGTTCTCGCTAACGTCAAGCTGTCGTACGGGCTCGGTGAGGACCAGCTGAACGTGCATCCGAATCAAATCATCTTACAGGGTGTGTTCGAGACGTTCAAATATGTGCGGCTGCGCGGGGAACGGTGTTGCGGCTGCCCCTACACCTGTTCCACGCGAGAGAAGCTGATGGAACACGCCAACCGTGACCATCCGGAAGGGTCGTCGACGGATGCGTTTGACGATCGGATCATGTGTGGACTGTGCCGTGTACAGTTCGGGGACGAAATCGAACTCGTGAAACATTTAAGCTTCTTTGTGAGCAGACAGCTCTTCTTCTGCACCATCTGCTACGAGTCGTTCCTGACACGCGAAAGTCTGCGGTACCATCAGGGGCATAGTAAGACCCATCAGCACGAGGTGCTAGAGCGTCACCAGGAGGGCGGTCTCAATGCGGAGGACTTTGTTGAACTCGATAAGCCGGATGTGGTGGAGCGGCTTGAGAAGCTCCTGGCGCTCAGGATGGTCAATCGCATGAAGGGGTCCCGCCACATGCGCATGCCGGACGCTCGGTTCATCAAGGAGGTGGTAGAGTACAACAACTATCGCAAGCTGGCCGTAATCGGTGAGCGGTGCTGCGGGTGCGGAATGTTTTTCGACACCACGGCCAACCTGAAGGAGCACTCCAGGGAGGTACACTTTACTCCGATGGCGCACGCGGACAGCCCGTGGAAACCGAACCACGAGTGCGAGATTTGTCACACGCAGTTCGAGGGCGAGCGTGGCCTCGCGCTGCACATGGCTGCGTCCCGGTTCAACCGAGGCAAAAGCACGACCAACCTGTACGTCTGCAAGCTGTGCGGGCTGCTTTTTACGAAAAAGTTCTGCCTCGGAAGACACATGCAGTTTGCACCCAATCACCTGTCGCGGCTGATCGAGGATGCGACGCGGAGAAAAGCGGACGATGCTCCGGGGGACGATGATAAGATCAGCCAGGATCCGCGGATTGCCGAAGCACTGCAGTTGCATAAGACGGTGCGCACGGACAAGGCCGGGGTCCAGATTGGGCATCACTGTTGCTTCCCCAAGTGTCGCGTACGCTTCACCGACGAGTCGGAGCTGTTGGAGCACGTGCACGATGAGCACGGCGGAAAGCGGCGGGAGTTTGAGTGCGAACGGAAGTCGGAACAAAACGTGTGCCCGGCTTGCTGCAAATCATTCGACACTCTGGCCAAACTTTACTGGCACCGCGTGCAGCGCTTCGTGCCGCGCCGATTCAACTGCAAACGGTGCGATAAAACGTTTGACAAGTGGCCAATGCTGAAAATACACGTTGCCACCGATCACGAAAACGCGCCGCCGAGCTTCCCGTGCACGCAGTGCAACAAAACGTTCATCAACGTGTCGCGGCTGCGGGTTCACGAGAAAATTCACGAAACGCACCTTCAGTTCGCGTGCGACGTGTGCGgggaccggttccggtacaACGGCTTGCTTTCGCGCCATAAGCGTGCTCTGCACTCGAGCGAGCTGCGCTTCGAGTGTAAGCTGTGCCCGAAAAAGTTTGCCGTCGCGGAAAAGCTGAAGATCCATCAGAGAGTGCACACTGGGGACCGGCCGTACGGCTGCACGTTCTGCAATCGCTCCTTTAGCCACTTTACCGACCGGAAGCGCCACGAAATGTCGGCCCACACGGGCGAACGGCCGCACCGGTGTCCGTTCTGTTCAGCGGCGTACATCCGCAACCGTGAGCTGGCCATGCACATGCGGAAGCACAAGGAACACGAAGAACCAACGGACGGCAAGATCGTCGAGCAATGA
Protein Sequence: MRRTSKRRKIVSKREEPAASARICSICTKEASEETTLALSAVVDDGNRNTVGSIIEEIASVKIKHTEQCICASCWKRVLEAHELRSAIRSSKIFGEASEEPPAECPVMIQPCPEEDGKVYEEYEYLMEYLENCGSNDHTYNDRDAEDDVSTVGEYYVKDEDQAEERSSFLLETAIMADTKPNDDENRSANITRQFEMPDPALIVHDELHERHRRVEVAGVRCCGCSFVAPNRKSLMQHSETVHAINIVDIGDYCPICFFKFATDKQLERHIQEFKSNNMYVCLRCNRFYNMRRRLYNHLLRCCDEELGGAADGEDSPDENEDDEEQENDELDDEAEVYGEEVPGEYDTIEYLLQQDDAPLRGIDRRRMHRYRAQFAKVLANVKLSYGLGEDQLNVHPNQIILQGVFETFKYVRLRGERCCGCPYTCSTREKLMEHANRDHPEGSSTDAFDDRIMCGLCRVQFGDEIELVKHLSFFVSRQLFFCTICYESFLTRESLRYHQGHSKTHQHEVLERHQEGGLNAEDFVELDKPDVVERLEKLLALRMVNRMKGSRHMRMPDARFIKEVVEYNNYRKLAVIGERCCGCGMFFDTTANLKEHSREVHFTPMAHADSPWKPNHECEICHTQFEGERGLALHMAASRFNRGKSTTNLYVCKLCGLLFTKKFCLGRHMQFAPNHLSRLIEDATRRKADDAPGDDDKISQDPRIAEALQLHKTVRTDKAGVQIGHHCCFPKCRVRFTDESELLEHVHDEHGGKRREFECERKSEQNVCPACCKSFDTLAKLYWHRVQRFVPRRFNCKRCDKTFDKWPMLKIHVATDHENAPPSFPCTQCNKTFINVSRLRVHEKIHETHLQFACDVCGDRFRYNGLLSRHKRALHSSELRFECKLCPKKFAVAEKLKIHQRVHTGDRPYGCTFCNRSFSHFTDRKRHEMSAHTGERPHRCPFCSAAYIRNRELAMHMRKHKEHEEPTDGKIVEQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00097263;
90% Identity: -
80% Identity: -