Abel008422.1
Basic Information
- Insect
- Anopheles bellator
- Gene Symbol
- Btbd7
- Assembly
- GCA_943735745.2
- Location
- OX030928.2:34482557-34486280[-]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 3 5.2e-14 1e-11 44.6 0.0 8 86 196 274 189 299 0.80 2 3 1.5e-06 0.00029 20.7 0.0 22 50 333 360 329 405 0.80 3 3 2.9 5.7e+02 0.4 0.0 72 106 428 463 421 465 0.87
Sequence Information
- Coding Sequence
- ATGAATCCTGGTCTATGGGGCTGTCTGATACCCTGTGGACTGTCATACTGGTGTGAGAGCAAGAGCGGTGGCGATCATCCTCCATGCATTACGACGGAGATGGGTGCAACAGCGTCAACCGACTGTCCCGGCTCTAGtgcaggaggaggaggaggaggtggaaGTGGTGGCGGTATGCTCGGTCTGTCAGGGATCACTTCAACGTCATCGGGGGCGGCGGGAGCCACTACGACTCCGTTATCCTCGGGAGGAGGTCTGGGCTACGGCCCGATGTGCGGCCCTGGCGGCGGTGTTGGTAGTTCCGGTATCGGTGGTCCGGGGGCTGTGGTGCGCGAAAGACGCAAGAAAGTAACGGGTTTCGCGACGCTGAAGAAAAAACTCATCCGACGACGCCGCTCGTCGAAAGCCTGTGATCATGGGCGGGTGCTGCGTGAGTTCGTGTCTAGTTGGAGTCCGATTGAGCTGTCCGCGTTACTGGAGGAGTATGAGTCGCTGGCCGCACTAAAGGACCTCTCGGTGCAGGCTGAGTTGGCTCGCCCGCCCGCTACCACCTTCAAACAGGACCTGGCCTCACTCTACGATTTCAGGCACTGCACCGACTGCGATCTGGTGTTTCGCGGAACCGTGTTCCCGGTGCACCGGGCAATACTGTCCGCACGCTGTTCTTACTTTCGCGATCTGCTCGCCGGATGCCCCGGATATGGGGCACGTATCTGTCTCGAGCTACGTTCTTCGCCGGTCGatgtggcgatgttttcgtcGCTTCTTCGCTACCTTTACACCGGGGATCTCTGCACGCACGATCCGAGCATCGACGTCAGTTTGCTGCGCCGGCTTGGAGAAGATTTCGGAACGCCCAATCCGCTGGAAAACGATCTGCGATACTTGCTGGAAACAGGGGACTATGCGGATGCAGCCATTGTGTTCACGTCTGAGGGTGGTGACTACCATCGACCAGATTCCGGTAGCTCAGAGTACGGCTTCCGGCCGAAGCTGGAGCTTCCTTGCCACAAAGCGATTCTGAGCGCTCGGTCGCCGTTTTTCAAGAACATGATACAGCGAAGGACACGGAACGTGAGTGAAGAGCATCAGCTGCACGGTACTGATCGGTCACTGCATGCAACAACACGCATCGTCCTGGACGAGAGTGTGATTCCGAAGCGCTATGCGCGTGTGTTGCTGCATGCTATCTACCTGGACACGGTTGATTTGTCGTTGATACTACGGGGCAACGGATGTGGTAGCGGCGCGGGAAGTCTAGGTGAGGTGCAGGCACTTACGCACACGGGCCGGGCACGGCCGTCTCCGTTGGAGGAGGCGATGGAACTGTACCAGATTGGGCGATTTCTCGAGCTGGATATACTGGCGCAGGGCTGTGAGGATTTGATACTCGAGTGGCTGTCACTTGAAACGCTGGCTACCGTACTGCGCTGGGGCAGCCAACCGCACGGGTCGGCCTGGGTGTATCGGCAGGCTTGTCACTATTTGCGCGAAGAGTTTTCGGCGATTGTTGGCTCGCCGGTCTTATTCCAGCTGGACAAATCGCAGCTGATCGAGGCTCTGCAGAACAATTTCCTGCAGGCATCGGAGCTGGAGGTGCTGCAGGCGGTGTTGAAATGGGGCGAACAAGAGTTGATACGTCGGATGGAGGACCGGGAACCGAATCTTCTCAGTCACACGGCCCACTCCGTAACTCGGAAGGGTATTAAGAAGCGCGACTTGAGCGATGTGGAACTCCGCGAGATACTTTCGGAGCTTCTGCCGCATGTGCGCATGGATCACGTGTTGCCACCGAATAACGAGATCCTCAATCAGGCCATCCGGCGCGGATTGGTGAGCACACCGCCGTCTCACATGATCGGCGACGAGCGCGAGAGTCTGCGAATTAATGCGTGGATTCGGGGTGGCAAAAATCATGGGTTGTTCGTACGGCCACGGCTGTTTATGCCATACTACGAAGAGGTGAAGGTTCTGCTAGAAGATCACATTGCATCGCAGCAGATCGAGCTGCTGCGGATGCGACGGGCGCGCCACATGCCCGACATTCCCGACACGCTCTACATGGTGTCACGGTTAAACAGTAACACGGGCACCAACCTCGGTGGTGGATCGGCGGCCGGAGTGGATGTtgtcgcggccaccgccgcctcgATTCCTGCGCCAGACGCTCCGACGATGGAATCGATGCAGAAACGGGAGCAAAAGCTACGCCAAGCTCCAGGCTGCCAGCGTGCGCTTGGTTTGTCGCTTTCAAGCCGATCGGAGATCAACCGACAGATCCGGTTGCGCGTCGTGCGGGAGTTCAACTTCCCAGACGAGGTTGCTGAATTGCTGGAGTGCGCCAATTGCTACTGCACCGACGGGGAAGCGAATGGAGCGGAGGAACACAAAGTGACACAGGATTATGATCAagacgatcaccaccaccaccaccatcaccaccatcatcatcatcatcattcgcaACAGAATCGgcaccagcatcatcggcaccaCGATCTGCACGCTAGCCAGCAATCGTTGGACGAGGAGTTGACGCCGCCCCCATCGCCAGCTCTGCCCGGCGACATTGGGCAGCAAGCCGTGCCCTGCTTCGGTCGGAATATGACATTCCCTCGCCAACAACCGACGGTCCCCAGTCAGTCGTACTCTTCtcagcaacaccagcaaccgTCACACCATCCGCTATCGCATCAGCAACATGCGTTGCTTTCTCACGGAACTGGGACAGGAGGAAGCAGTGTCGGTGGCTTACATGCGTCCGTGTCCAACAATCCCCTGGGGCTGCTGGGAACGCACCGACGTCAGGAGCTTCCATCCGTTATACCGGGGGGTGACATAGTGGCGTACCGTTTATCGGCACCAGCCGGCGGAGGAGGTGGTGAAATGGGTGCATGTTCAGATGGCCACCTGTCCGACGTAATGCCAGACGTGGCAATGGCCACGGCATCACTCGGACAGCTTCACTTGGGCGGAGGAAGTAGCTTAAACGGTGATGTCCACGAAAGCCTTCACCTGGATCTGGGTGATGGACCGAGCCACATGATCGGTGCAGCAGCGATTGGCGGACTACATCACAATATTTCGCAACACCATCGTATGGCCCCTAGCGGTCcagcaccagccaccagcacgTTCCATCATTATATGACACGAAACCTGTTGAACCCAATCCATCCGTCGAATTCGTCCCAGCAGTCGACGCAACAATCGTCCCATCAATCGACGGCATCCACATCGGGCTCGTCGGgctcgtcgatgtcgatgatggCTCATGCCACTACTCACGGTTCCCAAGCGTCTCTGTCTTTGGCTGCCAGtaatcaccaacaacaacagcaccatgGCTCACAGCAGCAACTGCTGAGCGTAGCGTCGTCatcccagcagcaacatcaaccgtCGCAGCAACTGCCATCATCGTCTTTGGCCCAACGATCTTCCTCGCCGTACACACTGCATCGAGCCAGTCCGAGTTTGCCGCATAGTTCATATCACTCTGGACCACCGCGCTTCTTATAG
- Protein Sequence
- MNPGLWGCLIPCGLSYWCESKSGGDHPPCITTEMGATASTDCPGSSAGGGGGGGSGGGMLGLSGITSTSSGAAGATTTPLSSGGGLGYGPMCGPGGGVGSSGIGGPGAVVRERRKKVTGFATLKKKLIRRRRSSKACDHGRVLREFVSSWSPIELSALLEEYESLAALKDLSVQAELARPPATTFKQDLASLYDFRHCTDCDLVFRGTVFPVHRAILSARCSYFRDLLAGCPGYGARICLELRSSPVDVAMFSSLLRYLYTGDLCTHDPSIDVSLLRRLGEDFGTPNPLENDLRYLLETGDYADAAIVFTSEGGDYHRPDSGSSEYGFRPKLELPCHKAILSARSPFFKNMIQRRTRNVSEEHQLHGTDRSLHATTRIVLDESVIPKRYARVLLHAIYLDTVDLSLILRGNGCGSGAGSLGEVQALTHTGRARPSPLEEAMELYQIGRFLELDILAQGCEDLILEWLSLETLATVLRWGSQPHGSAWVYRQACHYLREEFSAIVGSPVLFQLDKSQLIEALQNNFLQASELEVLQAVLKWGEQELIRRMEDREPNLLSHTAHSVTRKGIKKRDLSDVELREILSELLPHVRMDHVLPPNNEILNQAIRRGLVSTPPSHMIGDERESLRINAWIRGGKNHGLFVRPRLFMPYYEEVKVLLEDHIASQQIELLRMRRARHMPDIPDTLYMVSRLNSNTGTNLGGGSAAGVDVVAATAASIPAPDAPTMESMQKREQKLRQAPGCQRALGLSLSSRSEINRQIRLRVVREFNFPDEVAELLECANCYCTDGEANGAEEHKVTQDYDQDDHHHHHHHHHHHHHHSQQNRHQHHRHHDLHASQQSLDEELTPPPSPALPGDIGQQAVPCFGRNMTFPRQQPTVPSQSYSSQQHQQPSHHPLSHQQHALLSHGTGTGGSSVGGLHASVSNNPLGLLGTHRRQELPSVIPGGDIVAYRLSAPAGGGGGEMGACSDGHLSDVMPDVAMATASLGQLHLGGGSSLNGDVHESLHLDLGDGPSHMIGAAAIGGLHHNISQHHRMAPSGPAPATSTFHHYMTRNLLNPIHPSNSSQQSTQQSSHQSTASTSGSSGSSMSMMAHATTHGSQASLSLAASNHQQQQHHGSQQQLLSVASSSQQQHQPSQQLPSSSLAQRSSSPYTLHRASPSLPHSSYHSGPPRFL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00092262; iTF_00095145; iTF_00092908; iTF_00097176; iTF_00105928; iTF_00107781; iTF_00096491; iTF_00109253;
- 90% Identity
- iTF_00097176;
- 80% Identity
- -