Abel011217.1
Basic Information
- Insect
- Anopheles bellator
- Gene Symbol
- Hr39
- Assembly
- GCA_943735745.2
- Location
- OX030928.2:78765764-78769042[-]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.038 1.8e+02 1.0 3.0 76 185 98 222 48 250 0.52 2 4 0.73 3.5e+03 -3.3 2.8 127 167 356 396 319 433 0.45 3 4 5.4e-08 0.00026 20.2 0.0 1 21 591 611 591 621 0.93 4 4 8.1e-78 3.9e-74 250.2 0.0 176 408 718 946 687 946 0.91
Sequence Information
- Coding Sequence
- ATGAAAATAATGACGTCAACGGAAGTCACCGGATCGCCGACGAGTCGCGGCGGTAACGTGTCCGTCACGGCGATCAACTGCAGCGACGATGGCGGAGGAGGACCGGGTGGAACCGGGGGCGGTGGAGGCGGAACACCGGCGTCTCTAGACGCCAAGCTGGCCGCTGTTTCCTCTGCATCGGGCACCGCGACGCTCCtcagccacaacaacaacaaccacatcgcaagcaacaacaacagtgtgGTTGCgtgtagcaacaacaacaacaacagcgtAGTCGGTGGCCAGGGAACAGGGATTTTTGGGTCCGTGGGGAGCGCCAGCATCCGGATCACTGTGCCGAAGATGGAGGAATCGGATGAGTCCGATACGGAGCTGTCGAACATTGAGAAGTCGGTGACCGCGAACGGGGCGACCACCGGAGGAGGGGTGGTGGTCAGCATGCGGGAGCACGAGCGTAGCGCCAGCAAGAGCCTTCCGCGCCCAATGTCCTGGGAGGGGGAGCTctccgaaccggaagcgatgaTGGTGGACAACGAgagtagcagtagtagcagtagtggCGGCAGTAGCACCAGCAGTAGCCACAGTACCGACAAGATTGCCGTAGGTTTGATGGCCCCGATCGAACCGGTCGCGTTGAAGCAGGAACGATCGGAAgacgagcagcaacagcaacaccagcagcagcaggagtcCCAAGGAGTGCAAACTCCTGGACCGGGCATTACGGAACCCCTGGCACTGACGGCCAGCGCTACACAGCATGGGagtgtggtggcggcggcggcggcggcggcggcggcggcggcccccggcTTGCGGTCCAGTGTGGCCAGTAACTCACCGCTTCCCAGTCGACTGTTGATCAAACCCGAAGCCGGACTCCCCTTGATCACGCCCGGTTTGGCGTACAACGCGTCCAACATTCCACCCActagtggcggcggtggcctaCCGTCCGCCAAGAAGCTCCCGGATGTGATCAACCTCAAGTACGAACTGCCATCGACGACACCGGGCGGTTCGGAGCAAACCGGGAGTGCAGCGACAACGATCCACTCGCCGCTGCTCGTTCGCTCCAAAACCACGCTCCTTCCGGCCAACCCGAGTCCCGATTCGGCCATCCACTCGGTGTACACGCATAGCTCACCGAGCCAGTCTCCGCTCACGTCCCGCCACGCACCCTACACGCCGTCGCTCAGCCGAAACAACAGTGACGCATCGCACAGCAGCTGCTACTCGTACTCGTCCGAGTTCAGTCCGACCCATTCGCCGATCCAGGGACGTCACAGCATattcggcggcggcgctggtgccggtgctgggaGCGGTGTTAATGGGACCGCGAGCGCATCCTTCAACGGGTCGCCCCTGCACCACTCAGTATTATTCAAACCGATGCTGGACGCGggcgatcagcagcagcaccatcagcaggcTGCCCTCAAGCAgctggctgcggcggcggcggccgctgccgcccaGCAGGACGATGCGCTCTACGATGGAGAGCATCTGCCATCGCCCGGTATCTCCCGGCAGCAGCTAATCAACAGTCCCTGCCCGATTTGTGGCGATAAAATTTCCGGCTTCCACTACGGCATCTTCTCGTGCGAGTCGTGCAAGGGGTTCTTCAAGCGGACGGTGCAGAACCGCAAGAACTACGTGTGCCTTAGGGGGGCGGCCTGTCCTGTGACGATAGCGACGCGGAAAAAGTGTCCCGCCTGCCGGTTCGAGAAGTGCCTTCAAAAGGGAATGAAGCTGGAAGCCATTCGAGAAGATCGAACACGTGGTGGCCGATCAACGTACCAGTGTTCTTACACCCTGCCGGGCCCGCTGGTGAGCGCCGTTGGAGGGATGCAGCCAGGCAGTGactctccggtggccggtccgtTTCAGTACGGTGGAAGCGCGGTACGATCACCGTACGTTGGTGGCCCAGGCTCCGGTGGTCAGCAGATGAAAATGGAACCGGGTGACGGTGGTGGACCGATgatgggtggcggtgggctgAATGGGACGATGATCGGTGGATcgaacggtgacggtggtggttccggtgtcGGTAACCACCTACAACCAGGCATTCCAGTGCTGCTGCAGGAAATCATGGACGTTGAGCCACTGTGGCAGTACAACGCGGCCGAGCTGGCCCGGCTCAAtcagccaccgccggcggtaAGCAGTGCGGCCATCGCCAGCAACCCTCTACTCTCCAGTGCCGGCATCTCGTCCGAAAGCAGCCCGGATCTGATCGCCAACCTGTGCAACATCGCCGACCACCGGCTGTACAAGATCGTCAAGTGGTGCAAGAGTTTGCCACTGTTCAAGAACATTTCGATCGATGACCAGATCTGCCTGCTGATCAACTCGTGGTGCGAGTTGTTACTATTTTCCTGCTGCTACCGTTCGATCGCGACTCCGGGCGAGATCAAGATCTCGCTCGGGAAGTCGATCACGCTCGAACAGGTGAAGAACAGTGGATTGCAGACCTGCATCGAACGGATGCTTCACCTGACGGATCATCTGCGGCGGCTGCGAGTCGATCGGTACGAGTACGTCGCCATGAAGGTGATCGTTCTGCTGTCGTCCGACACCTCCGAGCTGAAGGAATCGGAAAAGGTACGCGCAAGCCAGGAGAAGGCCCTGCAAGCACTACAGGCCTACACGCTCGCCTACTACCCGAAAAGTCCGGCCAAGTTTGGCGAGTTGCTGCTCCGGATTCCAGAACTTCAGCGCACCTGTCAGGTTGGCAAGGAGATGCTGACGATCAAATCGAAGGACGGCGAGGAACCATCATTTAACCTTCTCATGGAGCTGCTCCGCGGCGAACATTGA
- Protein Sequence
- MKIMTSTEVTGSPTSRGGNVSVTAINCSDDGGGGPGGTGGGGGGTPASLDAKLAAVSSASGTATLLSHNNNNHIASNNNSVVACSNNNNNSVVGGQGTGIFGSVGSASIRITVPKMEESDESDTELSNIEKSVTANGATTGGGVVVSMREHERSASKSLPRPMSWEGELSEPEAMMVDNESSSSSSSGGSSTSSSHSTDKIAVGLMAPIEPVALKQERSEDEQQQQHQQQQESQGVQTPGPGITEPLALTASATQHGSVVAAAAAAAAAAAPGLRSSVASNSPLPSRLLIKPEAGLPLITPGLAYNASNIPPTSGGGGLPSAKKLPDVINLKYELPSTTPGGSEQTGSAATTIHSPLLVRSKTTLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQGRHSIFGGGAGAGAGSGVNGTASASFNGSPLHHSVLFKPMLDAGDQQQHHQQAALKQLAAAAAAAAAQQDDALYDGEHLPSPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAACPVTIATRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPGPLVSAVGGMQPGSDSPVAGPFQYGGSAVRSPYVGGPGSGGQQMKMEPGDGGGPMMGGGGLNGTMIGGSNGDGGGSGVGNHLQPGIPVLLQEIMDVEPLWQYNAAELARLNQPPPAVSSAAIASNPLLSSAGISSESSPDLIANLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCYRSIATPGEIKISLGKSITLEQVKNSGLQTCIERMLHLTDHLRRLRVDRYEYVAMKVIVLLSSDTSELKESEKVRASQEKALQALQAYTLAYYPKSPAKFGELLLRIPELQRTCQVGKEMLTIKSKDGEEPSFNLLMELLRGEH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00094505;
- 90% Identity
- iTF_00097096;
- 80% Identity
- iTF_00094505;