Abel004552.1
Basic Information
- Insect
- Anopheles bellator
- Gene Symbol
- FTZ-F1
- Assembly
- GCA_943735745.2
- Location
- OX030927.2:47422488-47430612[-]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 3 1.4e-11 6.5e-08 32.1 3.0 7 31 1 23 1 38 0.81 2 3 0.17 8.1e+02 -1.2 0.2 125 156 59 89 45 111 0.57 3 3 4.6e-78 2.2e-74 251.0 0.1 119 408 146 432 139 433 0.85
Sequence Information
- Coding Sequence
- ATGCGTGGCGGACGGAACAAGTTCGGCCCGATGTACAAGCGGGACCGGGCGCGGAAGCTCCAGATCATGCGCCAGCGACAGCTGGCCCTGCAGGCCCTCCgaggatcgatcggtggcggtgtcggcATCGGAACGCTCGGCTCGGACGGCGGTTCGCCGCAGCTCCAGGGTCTCGACTACCACCAGCCGTACTCGAGCATGCACATCAAGCaggaaattcaaattccgCAGGTCTCCTCGTTGACGTCGTCGCCCGACAGCTCGCCCAgcccgatcgcgatcgcgctcggCCAGGTGAACCCGCAGACGACGATATCGCTCAGCAGCAGTGGCGTCGGCGgcaatggcggcggtggcggtggcggtggcggcggtggaggaggcggcggtggcagcaatgggtccgggaccggcaccggcactggcgGTTCCAGCTCGACCAGCATCCAGAATCCGCTGTCCGACTCGAAGCTCTGGATGAGCGCCAACTCGACGACCGCCTCGCCCCACTCGCTCAGTCCGAAGGCGTTCAGCTTCGACTCGAATCCCACCAGCACGGCCGACTCCGGCAACCCGGCCGACACCCTAAGGCTAGTGGTATCGCCGATGATCCGCGAGTTCGTCCagtcgatcgacgatcgcgaGTGGCAGACGTCGCTGTTCTCGCTGCTCCAGAGCCAGTCCTACAATCAGTGCGAGGTCGACCTGTTCGAGCTGATGTGCAAAGTATTAGACCAAAATCTGTTCTCCCAGGTCGATTGGGCGCGGAACACGATATTCTTCAAGGACTTGAAGGTGGACGATCAGATGAAGCTGCTGCAGAACAGCTGGTCGGATATGCTGGTGCTCGATCACATACACCAGCGCCTGCACAACGGGCTGCCGGACGAAACCACCCTGCACAACGGGCAGAAGTTTGATCTCTTAGGTTTAGGGCTGCTGGGCGTACCGAGTCTGGCGGAGCACTTCAACGAGCTGCAGAACAAGCTGCAGGAGCTCAAGTTCGACGTCGGGGACTACATCTGCATGAAGTTTTTGCTGCTACTGAACCCTGACGTCCGGGGGATCACCAACCGGAAGACGGTCGTCGAAGGGTACGAGAACGTGCAAGCGGCCCTGCTGGACTACACCCTCACCTGCTACCCCTCGGTGCCTGACAAGTTCAGCAAGTTGCTCAGTATTATTCCGGAGATACACGGAATGGCGGCCCGGGGTGAGGAGCACCTGTACATCAAGCACTGCGCCGGCAGCGCCCCGTCGCAGACGCTGCTGATGGAGATGCTTCACGCGAAGCGAAAATGA
- Protein Sequence
- MRGGRNKFGPMYKRDRARKLQIMRQRQLALQALRGSIGGGVGIGTLGSDGGSPQLQGLDYHQPYSSMHIKQEIQIPQVSSLTSSPDSSPSPIAIALGQVNPQTTISLSSSGVGGNGGGGGGGGGGGGGGGGSNGSGTGTGTGGSSSTSIQNPLSDSKLWMSANSTTASPHSLSPKAFSFDSNPTSTADSGNPADTLRLVVSPMIREFVQSIDDREWQTSLFSLLQSQSYNQCEVDLFELMCKVLDQNLFSQVDWARNTIFFKDLKVDDQMKLLQNSWSDMLVLDHIHQRLHNGLPDETTLHNGQKFDLLGLGLLGVPSLAEHFNELQNKLQELKFDVGDYICMKFLLLLNPDVRGITNRKTVVEGYENVQAALLDYTLTCYPSVPDKFSKLLSIIPEIHGMAARGEEHLYIKHCAGSAPSQTLLMEMLHAKRK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00098452;
- 90% Identity
- iTF_00099692;
- 80% Identity
- iTF_00097136;