Basic Information

Insect: Anopheles arabiensis
Gene Symbol: ZFY
Assembly: GCA_016920715.1
Location: NC:38684447-38687919[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 3.7 1.8e+02 2.4 2.1 1 14 48 61 48 64 0.83

2 13 9.3e-05 0.0045 16.9 1.1 2 23 346 367 345 367 0.97

3 13 3.3e-06 0.00016 21.4 1.1 2 23 374 395 373 395 0.97

4 13 0.09 4.3 7.5 0.7 1 23 405 427 405 427 0.94

5 13 1.9 92 3.3 0.1 3 23 452 479 450 479 0.78

6 13 9 4.3e+02 1.2 1.1 2 20 486 504 485 507 0.64

7 13 5.1e-07 2.4e-05 24.0 2.7 1 23 545 568 545 568 0.96

8 13 0.0025 0.12 12.3 1.1 2 23 574 595 573 595 0.95

9 13 2.1e-05 0.001 18.9 2.2 1 23 600 622 600 622 0.94

10 13 0.0056 0.27 11.3 0.1 2 23 631 653 630 653 0.97

11 13 0.00031 0.015 15.2 0.5 2 20 660 678 659 680 0.93

12 13 4.7e-05 0.0022 17.8 0.4 1 23 691 713 691 713 0.99

13 13 0.00049 0.024 14.6 2.6 1 23 719 742 719 742 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	3.7	1.8e+02	2.4	2.1	1	14	48	61	48	64	0.83
2	13	9.3e-05	0.0045	16.9	1.1	2	23	346	367	345	367	0.97
3	13	3.3e-06	0.00016	21.4	1.1	2	23	374	395	373	395	0.97
4	13	0.09	4.3	7.5	0.7	1	23	405	427	405	427	0.94
5	13	1.9	92	3.3	0.1	3	23	452	479	450	479	0.78
6	13	9	4.3e+02	1.2	1.1	2	20	486	504	485	507	0.64
7	13	5.1e-07	2.4e-05	24.0	2.7	1	23	545	568	545	568	0.96
8	13	0.0025	0.12	12.3	1.1	2	23	574	595	573	595	0.95
9	13	2.1e-05	0.001	18.9	2.2	1	23	600	622	600	622	0.94
10	13	0.0056	0.27	11.3	0.1	2	23	631	653	630	653	0.97
11	13	0.00031	0.015	15.2	0.5	2	20	660	678	659	680	0.93
12	13	4.7e-05	0.0022	17.8	0.4	1	23	691	713	691	713	0.99
13	13	0.00049	0.024	14.6	2.6	1	23	719	742	719	742	0.98

Sequence Information

Coding Sequence: ATGGAACAGTTTGTAAATTGCGTACTGTGCTTGACTACCGAGCCGCAAAGCTTTCTCAAGGTGTACAATGAGGAGAAACAGGATACAGACATCGCGTCCGTAATAACAAAACATCTTTGGGTGAAACCGGCCAAGGATTCGTACGTATGTGATGAGTGCTGGAAATGTTTGAACGATTTCCACGAGTTCTACATCAAGCTCGAGAACATACACTATCCGCCCGATCCGGAGGATGTGTCATGCAATGCCAAAGACATCCGCCAGTATCTTTTCGAATTTCATCCCGTGGAAGACGTGAAGATCGAGGAACTGTCTCAGAATGCGGAGGACATGGAAGAAATAGAGTACGAGTATTTGGAAGCATGTAACGAAGAAACCATAGAGAATGAGAACGCCGAACGTTCCAGCGGTCGTCCGAAACGAGCCAGTGCCGCACAGGCGAACTATAAAATTGAAGCGGCCGAATCGGAGTGGGAAAAGGATTACCTTGCGACCAACGAGGACgagtacgacgacgacgacgacgaagcggACGCCGATTACAATGGCGATGAGAAGGAAGAGGTTGACTATCTGGAAGAGGATAATGATGACAGTGAGGTCATTAACTACGATAGTCCCTCGAAGGCAAAGCAAGAGCCGGGCACCAAAAAGGAGCCAGCCAGCGAACCGACGTCACCACCGAAAAGGGGTAGAGGTAGGCCGCCGAAGGCAAAAGCCGAGGTCGAAATCAAACCGGAACCGAAATCCAAGCTGCGCCGTCGGGGTCGTAAAAGAAAGGTTTCAGTTAGCAGCAGCGACTCGGAGCTGGAATCCGACTTTGACGATTTTATTGACGGCGAAGACTGGAAGAAGTATCGCAACACGTCGAATGATAAGGGGAGAAGATCGCTCGGTTTTCGGCAGCTGCAGGAAAAGATATTTTCATACGTGGATGAATTTATCTGCTACTACTGTCCGGAAAAAATCGTCTTCGAGCGGTTTCACCATGCGAATTTGCATTACAAGAAGGTACACAATGAGCCAGCCTTTCTGCGGTGTCCAAAGTGTGGCAAAAAGTGCTTCACACCGGGCGGATTTGTGAGCCACATGGAAACGCATGAAGATCCGGAGCGGAACAAGTGTAAAATCTGCGGCAAGGTTACGGATCAAAAAATCACGCTCAAGAAGCACATGCGAGCGCACCAGGAGAACCTGGAGAAGGACTTTCCGTACCCGTGCAGCCTGTGCAATCGGCGgttcgaggaggaggagaagcgcGACAAACACGAACGGCTGCACGGACGGAAAGTGATCATCAAGAAGGAGAAGGGTCGCGATCTGGAGCTGCTTGAGTTCTACAAACGCATCTACTGTGAAGTGTGTGAAGAGAAAAAGCCCGAATCAACCTCGTTCGATAACTTCTGGGATCTGAAGGTGCACATGGGTAATGAGCACAACAAAACGCCATTCCTAAAGTGTCCAATCTGCTTCAAGAAGAATGTGTGCCGCCAGCAGCTAATGGTGCACGTGGATGTACATAATAATCCAGAAAACTATCGctGTGAGGTGTGTAAGGAAATCCATCAGAATCTTGAAAAGCACATGATAAAAGCACACACCCCGGAAACGTCGTTACCGGACGAGAAAAATTACAGCTGCGAACATTGCGGAAAGATGTTCAAATATCAAACGAATCTTAAAAGTCATATCGATCGTATCCACGGTGTAAAGGATGTATCCTGTGACATTTGCCACAAATATTTCAATAGCAAAGCATTGAGCGCTCACAAACGTTCAGCCCACACGGACGAGATGTTTATGTGCGAACATTGTCCGAAAATGTTCAAAACGCGCAGCGGTCTCGAATCCCACAAGAGTGACCACGACGAAACGTTGCGCAAATCGGTGCAGTGTCTCATCTGTGGCAAGGAGATGCGCCGCGGTGCCAGCATGGCGAAGCACATGAAAACGATCCACTCGCAAGAGGATCCGGTCAGCTGTGATCTATGCGGCAAGGTGTTCCGCACCACGTTCCACATGATGCGGCACCGCGCCAACACGTGCTCGGCCACGATCGACTCACGGCCTTACAAGTGCGAAGTGTGCGGCAAAGGCTTTGCCATGAAGCTCACGATGACCGAGCATATGACAACGCACACGCGCACAAGCCTGTATCAGTGCGCGTTCTGTTTCAAGACCTTCGGGTACATTTCGAATCTGTACAAACACCGAAAGAAGGCTCACCCGCTCGAATGGCAGGAGGTGCAGGCACGGCCTGAACAGGGAATCGCCACCGTAATCGAAATACGCAATTAG
Protein Sequence: MEQFVNCVLCLTTEPQSFLKVYNEEKQDTDIASVITKHLWVKPAKDSYVCDECWKCLNDFHEFYIKLENIHYPPDPEDVSCNAKDIRQYLFEFHPVEDVKIEELSQNAEDMEEIEYEYLEACNEETIENENAERSSGRPKRASAAQANYKIEAAESEWEKDYLATNEDEYDDDDDEADADYNGDEKEEVDYLEEDNDDSEVINYDSPSKAKQEPGTKKEPASEPTSPPKRGRGRPPKAKAEVEIKPEPKSKLRRRGRKRKVSVSSSDSELESDFDDFIDGEDWKKYRNTSNDKGRRSLGFRQLQEKIFSYVDEFICYYCPEKIVFERFHHANLHYKKVHNEPAFLRCPKCGKKCFTPGGFVSHMETHEDPERNKCKICGKVTDQKITLKKHMRAHQENLEKDFPYPCSLCNRRFEEEEKRDKHERLHGRKVIIKKEKGRDLELLEFYKRIYCEVCEEKKPESTSFDNFWDLKVHMGNEHNKTPFLKCPICFKKNVCRQQLMVHVDVHNNPENYRCEVCKEIHQNLEKHMIKAHTPETSLPDEKNYSCEHCGKMFKYQTNLKSHIDRIHGVKDVSCDICHKYFNSKALSAHKRSAHTDEMFMCEHCPKMFKTRSGLESHKSDHDETLRKSVQCLICGKEMRRGASMAKHMKTIHSQEDPVSCDLCGKVFRTTFHMMRHRANTCSATIDSRPYKCEVCGKGFAMKLTMTEHMTTHTRTSLYQCAFCFKTFGYISNLYKHRKKAHPLEWQEVQARPEQGIATVIEIRN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00093670;
90% Identity: iTF_00093670;
80% Identity: -