Basic Information

Insect: Anopheles arabiensis
Gene Symbol: -
Assembly: GCA_016920715.1
Location: NC:53395746-53399939[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0075 0.36 10.9 2.7 1 23 23 46 23 46 0.90

2 14 0.0012 0.058 13.4 4.7 1 23 52 74 52 74 0.97

3 14 1.8 88 3.3 2.0 1 23 77 100 77 100 0.95

4 14 0.25 12 6.1 4.6 1 23 105 128 105 128 0.97

5 14 5.6 2.7e+02 1.8 1.0 1 23 135 163 135 163 0.85

6 14 0.00045 0.021 14.7 0.2 1 23 284 307 284 307 0.91

7 14 2.3e-05 0.0011 18.8 1.6 2 23 313 334 312 334 0.96

8 14 7.6e-05 0.0036 17.1 5.0 1 21 374 394 374 395 0.95

9 14 0.0031 0.15 12.1 3.3 2 23 420 442 419 442 0.97

10 14 0.00019 0.0092 15.9 0.8 2 23 453 474 452 474 0.96

11 14 7.5e-07 3.6e-05 23.5 0.3 1 23 480 503 480 503 0.96

12 14 8.1e-08 3.9e-06 26.5 4.1 1 23 509 532 509 532 0.98

13 14 0.00029 0.014 15.3 0.3 1 23 538 561 538 561 0.91

14 14 0.00013 0.006 16.5 2.9 1 23 566 589 566 589 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0075	0.36	10.9	2.7	1	23	23	46	23	46	0.90
2	14	0.0012	0.058	13.4	4.7	1	23	52	74	52	74	0.97
3	14	1.8	88	3.3	2.0	1	23	77	100	77	100	0.95
4	14	0.25	12	6.1	4.6	1	23	105	128	105	128	0.97
5	14	5.6	2.7e+02	1.8	1.0	1	23	135	163	135	163	0.85
6	14	0.00045	0.021	14.7	0.2	1	23	284	307	284	307	0.91
7	14	2.3e-05	0.0011	18.8	1.6	2	23	313	334	312	334	0.96
8	14	7.6e-05	0.0036	17.1	5.0	1	21	374	394	374	395	0.95
9	14	0.0031	0.15	12.1	3.3	2	23	420	442	419	442	0.97
10	14	0.00019	0.0092	15.9	0.8	2	23	453	474	452	474	0.96
11	14	7.5e-07	3.6e-05	23.5	0.3	1	23	480	503	480	503	0.96
12	14	8.1e-08	3.9e-06	26.5	4.1	1	23	509	532	509	532	0.98
13	14	0.00029	0.014	15.3	0.3	1	23	538	561	538	561	0.91
14	14	0.00013	0.006	16.5	2.9	1	23	566	589	566	589	0.94

Sequence Information

Coding Sequence: ATGCAGGATTTAGAAAAACATGCGAAAGTGCAACACTGTCCAACgaaacagcatcagcagcagtttCATTACTGCTCAGCGTGTCAGAAATCGTTCAAAACCAACCGTGGCCTACTGCAGCACAATACAATCTATCACGAGTCCCAAGAATTGCACCGCTGCTACATCTGTGAGCGACAGTTTCTCACAAAAACCAACCTACAAAACCATATGCGCTTTCACAAGGATCATGTGTGCAGCTTTTGCAACAACGGGTGGACAGACGAATGTCAACTGTTGGAGCACGTGCGTACCAGTCATAGAGATGGGATGTTTGTTTGCCGGTTTTGCAACAAGCAGGAACGGCTCAAGAAATGTCTCAATCGACACCTTCGCACAGCCCACGGGCAAGAGGTGAATCCGTATTACTGTGGGCATTGCCGGAATGCGGAGGCAACGCATAGCTACGACAGCTATGTAGCGTTGATGAACCATTTGCAGGAGCAACATTTCGCGGAAGATGATACCACTACTGCAGCGAAAGAATTGCATGGCACACTGCTAAATGCATCCCTGTTTGGCAAAGAGCTGGAATTGCTCGAGGACGACAAGGTAGTAGACGTTGAGCAGGATCGTTTTTTGCAGAACTTGCATCTCGTCCGGAGCGTTCCGGAGAGGCCGAAAACTTGTCAGCCGCTGGAACCGCGCATCGATCAACGGACGGTTCTGGAGGATTTTCTCGATGAAACGTTCGAGAATGATGAGATCTGGAACAAGTATATCGATAATGGAGAAGAGTATCTGATCGACGATTATGACATCTACCTCAAGGGAATGGATGAATCGGAGAAACAGGAAGAAGTGTGCATGTATCTGTGTCCACAGTGTAAGCAAGGGTTTCAGAGCCAGCGAAACCTGACGATTCATTTGGCGGAAGAGCACGACGTGTCCAGTTTGGTGTGCAATGATTGTGGAGCTAGTTTTACGCGGCATACAAGCTATCGAATCCATCGGCGCGAACATCTGAAGGAGAATGTTCGATTTCGTGAGAGCAACATACCCGAAATGGAGGAAGCACTTTCGCTAGTCCAAAGCACATCCTTGGACTATTCGGTGCAAGAGGAGGAAAGTGGTTATGTGTTTACCTGTAATCTGTGCGATCGCACCTTCCAGCGGAAGCACAACCTCGAAAAGCACAGATGTCTGTACTACGAACAACTGGAGCACTCCAACACTTCAGAGCAGCAGGGTGCAGGTGTCAATGGGACGGAATTGCAGCAATGCTCACACTGCCAGTTTCGCACGACATCAAGCCAGGAGCTGGAAACCCATCAGCAACGCATACATCAATCGGACATGGAGCCATCGGAGCCCGTCTACTGCATGCTTTGCGATCGTCGGTTCAGTTCCATATCCGGGCTGAAGTATCACTTGAAACGACACACAGGCATTAAGGCATTCGCTTGTTTGTACTGCGAGAAAACGTTTACGGCCAACTCGAACCTGAACGCGCACATTCGGAGTGTGCACAGCGCGCGAAAGGACTACCGGTGTGACGAATGCAACGAATCTTTTACCACGAAAGATCACCTGAACAAACACCAACGCTCGCGGCATCGGCAGGAgcgagcgtttgtgtgtggggagTGTGGCAAGAGCTACTTGCAACGGTCGCATCTGAACGAGCATGTTGCAGCGAGCCATCGGGAGGATCGGTACCTGTGCCATGTTTGCAATGGTTCTTACGTTACTAAAAGCTCCCTCAAACGGCACCAACAGCAGAAGCATGGTGTTATGAAAAGGGACGAAAAGTGA
Protein Sequence: MQDLEKHAKVQHCPTKQHQQQFHYCSACQKSFKTNRGLLQHNTIYHESQELHRCYICERQFLTKTNLQNHMRFHKDHVCSFCNNGWTDECQLLEHVRTSHRDGMFVCRFCNKQERLKKCLNRHLRTAHGQEVNPYYCGHCRNAEATHSYDSYVALMNHLQEQHFAEDDTTTAAKELHGTLLNASLFGKELELLEDDKVVDVEQDRFLQNLHLVRSVPERPKTCQPLEPRIDQRTVLEDFLDETFENDEIWNKYIDNGEEYLIDDYDIYLKGMDESEKQEEVCMYLCPQCKQGFQSQRNLTIHLAEEHDVSSLVCNDCGASFTRHTSYRIHRREHLKENVRFRESNIPEMEEALSLVQSTSLDYSVQEEESGYVFTCNLCDRTFQRKHNLEKHRCLYYEQLEHSNTSEQQGAGVNGTELQQCSHCQFRTTSSQELETHQQRIHQSDMEPSEPVYCMLCDRRFSSISGLKYHLKRHTGIKAFACLYCEKTFTANSNLNAHIRSVHSARKDYRCDECNESFTTKDHLNKHQRSRHRQERAFVCGECGKSYLQRSHLNEHVAASHREDRYLCHVCNGSYVTKSSLKRHQQQKHGVMKRDEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00104548;
90% Identity: iTF_00095790;
80% Identity: iTF_00093592;