Basic Information

Insect: Anopheles aquasalis
Gene Symbol: prg
Assembly: GCA_002846955.1
Location: NJHH01007478.1:47070-49561[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.24 15 5.8 0.8 1 19 228 246 228 251 0.75

2 10 0.027 1.7 8.8 0.3 1 23 257 280 257 280 0.96

3 10 2e-06 0.00012 21.8 0.6 1 23 286 308 286 308 0.96

4 10 2.1e-09 1.3e-07 31.1 1.6 1 23 314 336 314 336 0.98

5 10 1.4e-05 0.0009 19.1 1.2 1 23 342 364 342 364 0.97

6 10 0.00015 0.0097 15.8 0.3 1 19 371 389 371 391 0.97

7 10 5.9e-05 0.0037 17.1 0.8 1 23 500 522 500 522 0.98

8 10 4.2e-05 0.0026 17.6 0.8 1 23 530 552 530 552 0.99

9 10 0.0029 0.18 11.8 1.1 1 23 558 580 558 580 0.96

10 10 0.0012 0.076 13.0 0.1 3 21 588 606 586 607 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.24	15	5.8	0.8	1	19	228	246	228	251	0.75
2	10	0.027	1.7	8.8	0.3	1	23	257	280	257	280	0.96
3	10	2e-06	0.00012	21.8	0.6	1	23	286	308	286	308	0.96
4	10	2.1e-09	1.3e-07	31.1	1.6	1	23	314	336	314	336	0.98
5	10	1.4e-05	0.0009	19.1	1.2	1	23	342	364	342	364	0.97
6	10	0.00015	0.0097	15.8	0.3	1	19	371	389	371	391	0.97
7	10	5.9e-05	0.0037	17.1	0.8	1	23	500	522	500	522	0.98
8	10	4.2e-05	0.0026	17.6	0.8	1	23	530	552	530	552	0.99
9	10	0.0029	0.18	11.8	1.1	1	23	558	580	558	580	0.96
10	10	0.0012	0.076	13.0	0.1	3	21	588	606	586	607	0.95

Sequence Information

Coding Sequence: ATGCAGCAGTGCCGGTTATGTTTGGGCCAGGACAGGGAGCTTGTGGACATCTTCATCACACAGCGGCAGGAAGTGGAGAACGCGGCGGCCCCGCTGCACGTGCGTCTTCAGGAGTGTCTGCATCTCGATATACTCCAGAACGATAACCTACCCCGGTGGATCTGCCGGCAGTGCTTGGACCGTGTGGACGATTTTACTCGCTTCCGAGAGCGTTGTTTGGAGAACGAGCGTGCACTGCGGGacgccaacacacagcacggTCTGGGTGATACCCAGAAGGAGCACGAAGGCGTGAACTCGATTTATGACCTGGACACGagcgatgatgaggacgacgatgaagaaccGGAGATAGTAGTCATCAATCCGATGCGCGATTACGAAAGCTCCAACCAGAGCCTCCAGAATGGAACGTGCGATGATGCAGGGGAAGAGGAGCAACAGGAAGAGAATGATGATTCGGTTGCGGCCAGTGGTGCTGAAGCGATGAACACGTCCGCAGCAGATGCCCACGCGGAAGAGGAACTCGATGGATCGGGTGAtgcggaagaagaggaagaggaagaagatgaaatgCTAACGATGTATCCGGCTGGTACGGGTAGCAATGGTTTGGGACGACCAACGGAAGCCAATGCCGCCAGCGAACGCAATCATGAGGCCGTGCAGAAGACGACCGTGTTCACCTGCAAGTACTGTGACGTGGCTTTCGCTGCTTCGACAGCCTGTCAGCTGCACGAGATGCAGGATCACGATCTGTTGGCACCGTACGCCTGCCATCTGTGCAACTACCGCACGGCCATCCGGCTATCGTTGATTGCGCATCTTCGCGAGATTCACAGCATCCCGCGGCCGTATATCTGCGTCCAGTGTGGTAAAGGGTTCGTGCGTCGATCGGATCTCAAGAAGCACACGTTCGTGCACACCGGTGTCCGGCCGTACGCCTGTCAACAGTGTGGCAAGTCTTTTTCACGCAACACTAACCTCACGAAGCACATGCGCATTCACCTTGGCGTGAAGCCACACAGCTGCAGCTCCTGTCCGCGGACGTTCGTGAACAAAGCGGATTTGGTACGGCACCGTAATGTGCATCTTTCAGCGCGAACAGCCTTCACCTGCACCTGGTGTGGGAATGCGTACGCACGAAAGGACAATCTGCAGCATCACGAGGTTAACTGCGCCTCTAGAAGGCATGCCACCAGTGCGCCACCTTTACTACTGCCACCGATTACCGAAAACCATCTGTACGCGTACGGTGGACTGCACACAGATCCATCGATCGGTCAGAtggcatcagcaccaccgcaacacaacaccgaaccaccgacgacgacgatgatggatcAATCGAAAGGAATGGATTCGACGTTGAATGCAAGCGCAACGTTGGCCAGCTTCGCCAACATTATTCCCATGCAGATGATGGGTGAATCGGCGACTGGGGCCAGTGTGTCCGGTGCACGCACTGGTCCTGAAATGCCACCTTCGAACAAGGTGTACGATTGCCCGAGCTGCCCCAAGCGGTTCCTCAGCAAGGCAACACTCCGGAAGCACCAGCTTACGCACCCGCAGCGTCCCGATCCGGGTTACGAGTGTCCACAGTGTCAGAAACATCTGCCTGGCAAGCGTGAACTCGAGCGGCATCTAATGACGCACCTAGACCATAAACCGTTCGCTTGCAAAACGTGCGGCAAGCGGTTCCTGTGGAAGGATAAGCTGCAACGCCACGAGCGCATCCATCGTGAGGAACGCCACTTCGGTTGTCCCAACTGTGGCGCAACGTTCCAGCGGAGGACGGCACTGGCGACGCACCTGAAGATCGACTGTACCGCATCACTGATCGGTCGGGAGCAACAACGGCTCACGAACGATACGGCCTACGGCCTGCTGCCACCACATTCCATGCTTCCGTGA
Protein Sequence: MQQCRLCLGQDRELVDIFITQRQEVENAAAPLHVRLQECLHLDILQNDNLPRWICRQCLDRVDDFTRFRERCLENERALRDANTQHGLGDTQKEHEGVNSIYDLDTSDDEDDDEEPEIVVINPMRDYESSNQSLQNGTCDDAGEEEQQEENDDSVAASGAEAMNTSAADAHAEEELDGSGDAEEEEEEEDEMLTMYPAGTGSNGLGRPTEANAASERNHEAVQKTTVFTCKYCDVAFAASTACQLHEMQDHDLLAPYACHLCNYRTAIRLSLIAHLREIHSIPRPYICVQCGKGFVRRSDLKKHTFVHTGVRPYACQQCGKSFSRNTNLTKHMRIHLGVKPHSCSSCPRTFVNKADLVRHRNVHLSARTAFTCTWCGNAYARKDNLQHHEVNCASRRHATSAPPLLLPPITENHLYAYGGLHTDPSIGQMASAPPQHNTEPPTTTMMDQSKGMDSTLNASATLASFANIIPMQMMGESATGASVSGARTGPEMPPSNKVYDCPSCPKRFLSKATLRKHQLTHPQRPDPGYECPQCQKHLPGKRELERHLMTHLDHKPFACKTCGKRFLWKDKLQRHERIHREERHFGCPNCGATFQRRTALATHLKIDCTASLIGREQQRLTNDTAYGLLPPHSMLP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00092316;
90% Identity: -
80% Identity: -