Aaqu005463.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles aquasalis
Gene Symbol
-
Assembly
GCA_002846955.1
Location
NJHH01001566.1:1624-13894[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.00087 0.054 13.5 0.9 2 23 46 67 45 67 0.97
2 16 5.7e-05 0.0036 17.2 1.9 1 23 73 95 73 95 0.98
3 16 1.1e-05 0.00072 19.4 0.2 1 19 101 119 101 123 0.93
4 16 6.6e-07 4.2e-05 23.3 2.3 1 23 129 151 129 151 0.98
5 16 1.6e-06 0.0001 22.0 1.3 1 23 157 179 157 179 0.98
6 16 1.1e-06 6.8e-05 22.6 1.0 1 23 185 207 185 207 0.98
7 16 5.6e-07 3.5e-05 23.5 0.3 1 23 213 235 213 235 0.98
8 16 3.2e-06 0.0002 21.1 0.3 1 23 241 263 241 263 0.97
9 16 1.3e-06 8e-05 22.4 1.2 1 23 269 291 269 291 0.98
10 16 1.3e-06 8e-05 22.4 0.5 1 23 297 319 297 319 0.98
11 16 4.5e-06 0.00028 20.7 0.3 1 23 325 347 325 347 0.97
12 16 1.3e-05 0.0008 19.2 1.0 1 23 353 375 353 375 0.98
13 16 4.3e-07 2.7e-05 23.9 0.3 1 23 381 403 381 403 0.98
14 16 3.8e-07 2.4e-05 24.0 1.4 1 23 409 431 409 431 0.98
15 16 2.9e-07 1.8e-05 24.4 1.8 1 23 437 459 437 459 0.97
16 16 0.078 4.9 7.3 0.6 1 21 478 498 478 499 0.94

Sequence Information

Coding Sequence
CAAACCACATTCGAGGATGGCGAAATCGAGCTCGGACGCAACGAGATGCTTAACCACGAGGCGCTGACTGACAATAAGCACTCACTAGCCTTGTCCATCTCCCTGAGCAATACGCTCATTAATCTCAACAAAATCAAGTGTCCACAATGCCGGAAGCGCTTTGATACGGTGGAAGAAATGCAGCTACATCAGACCAAGCACTTGACAGAGAATAAGTTTAAATGTGAAATATGTAGTAAGGAATTCCCTAGCCATAGTTCCATGTGGAAGCACACCAAGGCACATACCGGAGAACGTCCCTTTGTGTGTCAGATTTGTAACAAAGGCTTTACTCAGCTAGCCAACCTTCAGCGGCATGATCTCGTCCACAACGGACTCAAACCATTCAAGTGTCCGATttgtgaaaagtgttttaCCCAACAAGCGAACATGTTGAAGCATCAACTACTTCATACGGgcCTCAAACCCTACAAATGTCCCGTGTGCCAGAAAGCATTTTCGCAGCACGCTAATATGGTCAAACATCAAATGCTTCACACagGTCTGAAGCCCTATAAATGTCCAGTATGCGAGAAGGCGTTCACCCAACATGCAAACATGATTAAACATCAAATGCTACATACAGGACTTAAACCGTTCAAGTGTCCCGTGTGTGAGAAGGCTTTCACCCAGCAGGCCAACATGGTGAAACATCAAATGCTGCATACCGGCGTGAAACCGTACAAGTGCTCCACCTGTGGAAAAGCCTTCGCCCAGCAGGCGAACATGGTTAAGCACGAGATGCTGCACACTGGTATCAAGCCGTACAAATGTCCCACTTGTGATAAGGCATTTGCACAGCACGCCAATATGATGAAACATCAAATGCTTCACACCGGATTGAAGCCGTATAAGTGCAGCACATGCGATAAGGCATTTGCCCAGCAGGCCAACATGGTGAAACATCAGATGCTGCATACCGGTTTAAAACCGTACAAATGCAATACCTGCGACAAGGCATTCGCTCAGCAGGCCAACATGGTCAAACACGAGATGCTTCATACGGGAATAAAACCCTATAAATGTTCAGTGTGTGAAAAAGCCTTTGCCCAGCACGCGAACATGGTCAAACATCAGATGCTTCACAGCGGAATCAAACCGTACAAATGTCCCACCTGCGACAAAGCGTTTGCCCAGCAGGCCAATATGGTTAAGCATCAGATGCTCCATACGGGAGAAAAACCGTTCAAATGCAAAAGCTGTGATAAGGCTTTCTCGCAACGTGCCAATCTGAAGAAGCATGAAATGGTGCACCTTGGTATTCGGCCCCACACGTGTCCACTGTGTCCTAAGTCCTACTCGCAGTATTCCAACCTGAAGAAGCACCTGCTCGTGCACCAGAAGCAAGCAATTaagcaggagcaacagaacGGGCAAGTGATGGTGATTCTGTACAACTGCCAAACGTGCAAGATGCAGTTCGAAGACATAATCGAATTCGAGCGCCACACGAAAAAATGTGATATAAGCAGTgtagcccagcagcagcagcagcagcagcagcacagcgtgAAGCTGGAGAATATCAAGAGCGAGGTCGACATCGACGGTAGCTCCAACTCCGGCgggctacagcagcagcatatcggGACCACCAACAATGGTGGGCCCATTCCGTTGAATGtcagccaacagcaacagcagcaacaacaacaacaacaacaacaggtgtCACAACcggcacaaccaccaccaccgccaccgtccgcACCACCGACCTCCCAGATGCATCTGCCATCCGCCATCCTGACGTCGGTCAtttcatcgtcgatcggttcgaACGTGACAGCACATTCGCTGGCAAACGCGATACACCTTCCACACGCTGGTCACGTGACGACGAATGGTGTTATTCTAGGAGGGGGCATCCCTACTGGACATCCGCAtgcccaacagcaacacacgcCACCCGGTATCGGTCTGTCACAGCACACGAATCattcgcaacagcagcaacaggcccaccagcaacagcagactcaccagcagcagctctctccTGTCGGTagtcaccaacagcaacagcagcaacaacaacagcaacagcagcagcaacaacaacagcagcagcagcagcagcagcatttggttttgcagcaacagcacaatcTTCCAattcatctgcagcagcaactgtcaCATCATTTGATCACTAGCCATCTGCCGCACCATACGGCCCCGGGCCAGGAACATGGTGGCGCAACCGAGCTACACCATCAAGTGAACTTCCACCATCCGCACATCTCACATCTGCCCAATCTGTCGCACAAAATTCTGTCGCCGTTGTTTCACATTCCATcgttcaacaacaaccacagcacatAA
Protein Sequence
QTTFEDGEIELGRNEMLNHEALTDNKHSLALSISLSNTLINLNKIKCPQCRKRFDTVEEMQLHQTKHLTENKFKCEICSKEFPSHSSMWKHTKAHTGERPFVCQICNKGFTQLANLQRHDLVHNGLKPFKCPICEKCFTQQANMLKHQLLHTGLKPYKCPVCQKAFSQHANMVKHQMLHTGLKPYKCPVCEKAFTQHANMIKHQMLHTGLKPFKCPVCEKAFTQQANMVKHQMLHTGVKPYKCSTCGKAFAQQANMVKHEMLHTGIKPYKCPTCDKAFAQHANMMKHQMLHTGLKPYKCSTCDKAFAQQANMVKHQMLHTGLKPYKCNTCDKAFAQQANMVKHEMLHTGIKPYKCSVCEKAFAQHANMVKHQMLHSGIKPYKCPTCDKAFAQQANMVKHQMLHTGEKPFKCKSCDKAFSQRANLKKHEMVHLGIRPHTCPLCPKSYSQYSNLKKHLLVHQKQAIKQEQQNGQVMVILYNCQTCKMQFEDIIEFERHTKKCDISSVAQQQQQQQQHSVKLENIKSEVDIDGSSNSGGLQQQHIGTTNNGGPIPLNVSQQQQQQQQQQQQQVSQPAQPPPPPPSAPPTSQMHLPSAILTSVISSSIGSNVTAHSLANAIHLPHAGHVTTNGVILGGGIPTGHPHAQQQHTPPGIGLSQHTNHSQQQQQAHQQQQTHQQQLSPVGSHQQQQQQQQQQQQQQQQQQQQQQQHLVLQQQHNLPIHLQQQLSHHLITSHLPHHTAPGQEHGGATELHHQVNFHHPHISHLPNLSHKILSPLFHIPSFNNNHST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00102068;
90% Identity
iTF_00092285;
80% Identity
-