Basic Information

Gene Symbol
-
Assembly
GCA_013758885.1
Location
NC:27180465-27183186[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.028 1.4 8.9 2.5 1 23 277 300 277 300 0.91
2 13 0.58 28 4.8 1.8 1 23 306 328 306 328 0.96
3 13 0.17 8 6.5 3.6 1 23 332 355 332 355 0.97
4 13 0.0046 0.22 11.4 0.4 1 23 357 379 357 379 0.97
5 13 2e-06 9.6e-05 22.0 0.6 2 21 388 407 388 408 0.95
6 13 5.6e-05 0.0027 17.4 0.6 2 23 458 480 457 480 0.95
7 13 0.45 21 5.2 3.2 1 22 488 509 488 510 0.81
8 13 0.0014 0.067 13.0 0.3 3 23 529 550 528 550 0.92
9 13 4e-05 0.0019 17.9 2.3 1 23 557 580 557 580 0.94
10 13 0.0011 0.052 13.4 3.2 1 23 587 609 587 609 0.97
11 13 2.9e-05 0.0014 18.3 3.5 1 23 615 637 615 637 0.97
12 13 5.2e-05 0.0025 17.6 1.8 1 23 643 665 643 665 0.98
13 13 6.2e-05 0.003 17.3 0.3 1 23 671 694 671 694 0.97

Sequence Information

Coding Sequence
ATGCCGCCAAAGGTGGCCGCCCCCATCCAGCTGAACAGTCGAACCTGCCGCCTGTGCCTGAACAACTCGCAGGAGCTTCTATCTTTGGAGGTTGCTCTCACGCAAGAAGAGCTGCAGAATGTCATCGCCAAGTTTCTAGAGATCGACCTGAAGGAAAACTCTCCGTTTTGCAACGCCTGCCCGAGCTGCATTGACGAGGTGCGTCGGATAGAGTACTGGAGGGAATTCTTTATGGGCAAGAATCGCATGTTCGATGTTCTTTGGACGCAACACAAACGATTTCAAGGCAACAAAAAGACCATGTTCTTCGGTGACGAGATCGTTCGAGATAAAAGGGTGATCGCGGATGGCTACATTATTGATCACATCGTGTTGGAGCAGAACGATATGTACATTGATTCGATGGACGAGTTCGTaaaggatgaagatgatgacgatcagtGTGTGATTTTGAGCGAAGTCAAGCAAGAGGATACCGAACCGGACTCTTCACTAGTCAACGAGGAACTGGTGTATGAGGAAGTTGCCGTGGAGGTCGAAGACATCGAGGATGGAACGGTGCTCATGGCGGACGTAAAGCCACAGCCGGATGACATCGATGAAGATAGCATGATGATAGAGGAAGGGGACGAAATCTTGCTGGAGGGAGAAGAGGAGGGGATACTCGAGGAGCATATAGACGAGCTGCAGATAGCAAGGGAAGATTCGACAGCGGAGGAAACCGGCGAGGATGTTAGCCAAAATGAACCGGAAAGTGAGCAGCCGATTGAGGAGAGTGGCAAGATCGAGGTGCTGGAAATCAACGGTGGACTGTACGATAGCGCACTCCACTGTTGCTACCTCTGCACGCAGGAGTTCGACGACGCGGACCAGCTTAATCAACACTTTCAAGAGGCCCATCAGGATACGCTGCCGTTTCACTGCGACAAGTGCCTCTCCTATTTCTCCTCGATGGAGGACGTGAACCAGCACCTTGTCACGCATGTGTACCCGTACGTGTGTCTCTACTGTCGACAGCAGTACAGCCACGAGGTACTCCTGGTGGAACACAACAAGACGTGCCATGCCTACCGCTGTCCGCACTGTTCGGCGGAGTTTGAGATCATGGCCCAGCTGAATGCCCACAAGAAGGAACACGCTGCCATACTGcggcaatcgaatcgatgcaAAACCTGTGGCCGAACGTTCACGCAGCAAGGCAATCTGTTACGGCACGTGCGGCTGCGGTCCTGCGTTAAGccggcaccgaaaatggtgaaaacggGCAATCAGAAAGCCACGGAAGTGCATGCTCTCCGTCCTAAGAAGAGACCATTGCCAGCCGACGATGCATCGGAGAACAGCGAAGAGGTGCGCTCGCGGAATCTGGTAGTGTGCCAGGTGTGTAGCCATCGGTtcgagagcaacagcaacctaGCACGGCACATCGATCGAGAACACGCCGAGTTCAAAATTCCGCTGTACAACTGCGACGTTTGTCCCAAAAAGTTCACGGTATTTGAAAAGTGTGTCCGCCATCGCGCATTCCACCGGCATTCGAAGCCAAAGGAGAAGCCGGCGAAAAAGGAGGATTCCGACCGGAATTGTAAACTGTGCGGTAAAGAGTTCCGCATCGAGTTTCAGCTGTTGCGCCATCTAGCCGAAGAGCACATGCTAGCGCTGCAGCTGTTCGAGTGTGACCAGTGCGATCGgaagttttccaccgaaaccaaGCTACGAAAGCATCTGTACAATAGCCACCGTGAGAACAAGACGCTCTACGTTTGCTCGCACTGTGGGCAGAAGTTCGAGAAGAAGCTCACACTGAAGGACCACGAGACGAAGCATCTCGGCGAACCGGCGTACCGGTGTGAAATCTGCACTAAAACCTTTATCCACAAGCACAGCCTCGACCGGCATGCGCTCGTGCACAGCGACGCGAAGCTGTTCGAGTGTGAGTTTTGTTTGAAGCGCTTCAAGCGCAACACAACGCTGGTAATACATCGCAGGATACACACGGGCGAAAAGCCTTACTCCTGCGATGCGTGCGATCTTCGTTTCATCGACTCCAGTACTCTCATCAAGCACCGGCAGCGTGCGCATTCCAAAGCCGAATGA
Protein Sequence
MPPKVAAPIQLNSRTCRLCLNNSQELLSLEVALTQEELQNVIAKFLEIDLKENSPFCNACPSCIDEVRRIEYWREFFMGKNRMFDVLWTQHKRFQGNKKTMFFGDEIVRDKRVIADGYIIDHIVLEQNDMYIDSMDEFVKDEDDDDQCVILSEVKQEDTEPDSSLVNEELVYEEVAVEVEDIEDGTVLMADVKPQPDDIDEDSMMIEEGDEILLEGEEEGILEEHIDELQIAREDSTAEETGEDVSQNEPESEQPIEESGKIEVLEINGGLYDSALHCCYLCTQEFDDADQLNQHFQEAHQDTLPFHCDKCLSYFSSMEDVNQHLVTHVYPYVCLYCRQQYSHEVLLVEHNKTCHAYRCPHCSAEFEIMAQLNAHKKEHAAILRQSNRCKTCGRTFTQQGNLLRHVRLRSCVKPAPKMVKTGNQKATEVHALRPKKRPLPADDASENSEEVRSRNLVVCQVCSHRFESNSNLARHIDREHAEFKIPLYNCDVCPKKFTVFEKCVRHRAFHRHSKPKEKPAKKEDSDRNCKLCGKEFRIEFQLLRHLAEEHMLALQLFECDQCDRKFSTETKLRKHLYNSHRENKTLYVCSHCGQKFEKKLTLKDHETKHLGEPAYRCEICTKTFIHKHSLDRHALVHSDAKLFECEFCLKRFKRNTTLVIHRRIHTGEKPYSCDACDLRFIDSSTLIKHRQRAHSKAE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00098545;
90% Identity
-
80% Identity
-