Basic Information

Transcription Factor Domain

TF Family: PC4
Domain: PC4 domain
PFAM: PF02229
TF Group: Unclassified Structure
Description: This domain is found at the C-terminal end of Activated RNA polymerase II transcriptional coactivator p15 from humans, YdbC from Lactococcus lactis, and other PC4 family members. p15 has a bipartite structure composed of an N-terminal regulatory domain and a carboxy-terminal cryptic DNA-binding domain [1-4]. Activity is controlled by protein kinases that target the regulatory domain.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 5.7e-06 0.13 13.6 0.2 8 29 13 34 10 39 0.87

2 3 2.8e-07 0.0063 17.8 0.0 28 51 47 71 43 72 0.91

3 3 1 2.3e+04 -3.2 0.0 37 45 191 199 190 200 0.81

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	5.7e-06	0.13	13.6	0.2	8	29	13	34	10	39	0.87
2	3	2.8e-07	0.0063	17.8	0.0	28	51	47	71	43	72	0.91
3	3	1	2.3e+04	-3.2	0.0	37	45	191	199	190	200	0.81

Coding Sequence: ATGGCTGCTTTATTGAAGTTAGGACCTCGAGGATATCATGCTACGGTCCAGAAATTCAAAAACGATACTCGAATTCATATCCGAAAGTATATTGAAATGGATGTTCATAAGTACGAATTGGTTTTCCGAACCGGAATCGATTCTGATGGAGCAAAGTACCCTACAAAGCAGGGAGTAGCTCTATCTATCGAAGAGTTTCAAGAACTGAAGAAAGTGATTCCCAAGCTGAGGGAAATAATCGAAGCCATGCAGGATACCAGTTGTGTATCATCTCAAGAGAAAATCCAAGATACAAAGCTACCCGAAAAACAAGTGCCTGAAGAAACACCACGTCAACCAAAAAGATCACAATTTGTTTCACTTTTGAAGTACAACATGAACAAGTCAGGATATCCAATCGAATTTCAGCCTATAGATGGCGCCGGTGTTGAGAATCAGAAGAATTTCTGCAGTGGCGAGATTCCAATGCTCTTTCTGGCGCCTGATAGTCCGGAGAATATGAATATCAAAGAACTATTCGCCAATGTTATGACACGGAAACAGGATATCAAACAAGTATTTCGTATCGCTAAAGGCATTCTTCTTCAACAGACTGAGTTGATTCAAAGTGTCGAAAGTCCGGCAGCGATCGTCGGTGAAGTTCGTGGTAATCACCTCTACCTGGCCAGCATATGTGAGAGTGTTTGTCCACTCTTTACCCACATGACATCGACGAATTTCGTCTTTTGTGGCAACTATTTCGACGACGATTCCGGCCTTGAAGCGGTCATCTTTCTCCTGTCAGCCAAAACACACTCTGATATCGGCAAATTTCCAATACGTTAG
Protein Sequence: MAALLKLGPRGYHATVQKFKNDTRIHIRKYIEMDVHKYELVFRTGIDSDGAKYPTKQGVALSIEEFQELKKVIPKLREIIEAMQDTSCVSSQEKIQDTKLPEKQVPEETPRQPKRSQFVSLLKYNMNKSGYPIEFQPIDGAGVENQKNFCSGEIPMLFLAPDSPENMNIKELFANVMTRKQDIKQVFRIAKGILLQQTELIQSVESPAAIVGEVRGNHLYLASICESVCPLFTHMTSTNFVFCGNYFDDDSGLEAVIFLLSAKTHSDIGKFPIR

Sequence clustering based on sequence similarity using MMseqs2