Basic Information

Insect: Andrena praecox
Gene Symbol: ZEB2
Assembly: GCA_963932275.1
Location: OZ010729.1:13611318-13616727[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 0.0013 0.19 13.3 0.5 2 23 274 296 274 296 0.96

2 20 0.0022 0.31 12.6 0.8 1 23 300 322 300 322 0.98

3 20 2.7 4e+02 2.8 2.7 2 23 329 351 328 351 0.93

4 20 2.1e-05 0.0031 18.9 2.0 1 23 358 381 358 381 0.97

5 20 2 2.9e+02 3.3 0.3 1 12 386 397 386 400 0.87

6 20 0.00029 0.042 15.4 2.4 1 23 416 438 416 438 0.98

7 20 1.8 2.6e+02 3.4 1.0 2 23 443 464 442 464 0.92

8 20 0.016 2.3 9.9 1.3 1 23 470 493 470 493 0.94

9 20 5.5e-05 0.008 17.6 0.8 1 23 503 525 503 525 0.96

10 20 2e-06 0.00029 22.2 5.1 1 23 529 551 529 551 0.98

11 20 6.4e-06 0.00092 20.6 1.1 1 23 557 579 557 579 0.98

12 20 9.7e-07 0.00014 23.1 0.9 1 23 585 607 585 607 0.99

13 20 0.074 11 7.8 0.2 2 19 726 743 726 745 0.89

14 20 0.0034 0.5 12.0 0.3 1 23 752 774 752 774 0.96

15 20 0.016 2.3 9.9 5.3 1 23 780 803 780 803 0.96

16 20 0.00047 0.068 14.7 3.3 1 23 810 833 810 833 0.97

17 20 8.1 1.2e+03 1.4 12.1 2 23 871 892 870 892 0.96

18 20 0.019 2.7 9.7 1.9 1 23 896 919 896 919 0.95

19 20 0.21 30 6.4 2.5 1 23 925 947 925 947 0.96

20 20 3.8e-06 0.00055 21.3 1.3 1 23 953 975 953 975 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	0.0013	0.19	13.3	0.5	2	23	274	296	274	296	0.96
2	20	0.0022	0.31	12.6	0.8	1	23	300	322	300	322	0.98
3	20	2.7	4e+02	2.8	2.7	2	23	329	351	328	351	0.93
4	20	2.1e-05	0.0031	18.9	2.0	1	23	358	381	358	381	0.97
5	20	2	2.9e+02	3.3	0.3	1	12	386	397	386	400	0.87
6	20	0.00029	0.042	15.4	2.4	1	23	416	438	416	438	0.98
7	20	1.8	2.6e+02	3.4	1.0	2	23	443	464	442	464	0.92
8	20	0.016	2.3	9.9	1.3	1	23	470	493	470	493	0.94
9	20	5.5e-05	0.008	17.6	0.8	1	23	503	525	503	525	0.96
10	20	2e-06	0.00029	22.2	5.1	1	23	529	551	529	551	0.98
11	20	6.4e-06	0.00092	20.6	1.1	1	23	557	579	557	579	0.98
12	20	9.7e-07	0.00014	23.1	0.9	1	23	585	607	585	607	0.99
13	20	0.074	11	7.8	0.2	2	19	726	743	726	745	0.89
14	20	0.0034	0.5	12.0	0.3	1	23	752	774	752	774	0.96
15	20	0.016	2.3	9.9	5.3	1	23	780	803	780	803	0.96
16	20	0.00047	0.068	14.7	3.3	1	23	810	833	810	833	0.97
17	20	8.1	1.2e+03	1.4	12.1	2	23	871	892	870	892	0.96
18	20	0.019	2.7	9.7	1.9	1	23	896	919	896	919	0.95
19	20	0.21	30	6.4	2.5	1	23	925	947	925	947	0.96
20	20	3.8e-06	0.00055	21.3	1.3	1	23	953	975	953	975	0.99

Sequence Information

Coding Sequence: ATGTCGACGATCGCGGATATGTCTGCTACGCGAACCCCAGCGCGACCACTCTTTGTAGCCTGCCATGGGGCTCCATTTCTGGATCACGAGGGAAAAAACCAACCGGCGATCCAAGTCAAGTCTCCGCCGATTTCTGACGACGAGGAGAACAACCATACCGCGCCCAACGACCTTGAAAATAACTACGACGATTTCGGCGACGAGAGCTCGCCGGACGAGGATGACGATACGTTGAGCGACAATAACGATGACATGTACATGAACGGTGGTAATTATCGTTTGTTATCGAGCACGGTTAATGATACTCCCTCCCCGAACATTGTCGACGACGATACGCCGTCGAGGGTGGGCGACAATGGGTTCCAGGAAGGGATAGATACATCTGTGACCTCGGTGAAAACTGTGCTGGTGCCAGTTCGAGACCCAGTAACAAGGGAACTTAAGAACGTGTTGGTGCCAGTTGAAGTGAAGGACTCAACGGGGATGAATATAATTAAAAGCGTCCTAGTACCGGTCGAGGACGAGGACGGGCTGATGTCGTATCAGATTAAGAAGTTCGTGGTGCCCATCAAGAGTCAGCCGATTGTGCCCCAGAAGAAAACTAAACCGTTGCCCAGCAAGAACGCCGCTAAATCGGGAATTAGGAAGAAGGGGGGAAAGAAGGAAGCGAAGAAGGAAGTGGAGAAGGCGAAAGAGGCCGGGGAAGATGTGACAGAAGATAAGACAGAAGAAAGCAAAGGGGATGGTGAGCCAAAGGAAGCAGCTGGAGCAGATACGCCGAAGGAGGAAGTGGATCGAATATTGGATAATGTGAAGAACAGTTGCCCATATTGCCAGAAGAACTTCGAAGACGAGAAGCAAGTGGACAGACACGTAAAAAGGATTCACAAGAAACCATTCCGCTGTAGAGTATGCTACAATTCCTTCGTCGCGAAGGAGTCCCTGAAGGACCACATGAAGGGTCACGATAAGGACGCGTTGCTGGAGTGCCCCTTCTGCCACCAGAAGTACAAGTGCATGGCTGGGCTGAGATACCATCAGATTCGCGCGCACAGCACCATAGAGCCAAAGTACGTGTGTGACCAGTGTGGTAAGCGCTTTAAATTGAAGCATGACCTGAGCTCTCACATCGAGAGGTCCCATCTGACCGACACCTACATCTGCAGGTTCTGCGGCAAGTCCGTGAGGAACATAAAGCAGCACGAATGGTATCACGAGAAGTCGGCCAAGAAGTACGAATACTCTTTCAGCTGCCACCTCTGCCCCACAAAGTTCAGGCGACGAACTGGCCTCGACAACCATCTGCTGATGCACAAGAACAGCATCAAGTGCGGCCAGTGCAGCAAAGGCTTCATGTGCGACTCCGAGCTGGAGGACCACAAGATCAGCCACACAGGCGAGGTGACGTACGTCTGCAAGTACTGCCGCAACGCTTATTCGGAGAAGTCCTGCCTGGTGGCGCACAAACTGCTCGCGCACGGTATACAGCAACGCGTGCCTAAGGAGTTCCAGTGCAACGTCTGCAGCAAGAGCTTCGCCACCGAGCTAAGCCTGCGCAAGCACGTCACCTTGCACTCGAAGATGTTCTCCTGCTCTCACTGCGACAAGGAGTTCGCCAGCAGCCACAATCTGAAGCTGCACATTCGGAAGCACACGGGCGAGCGACCCTACGAGTGCAAGTTCTGCAAGAAGTCCTTCGCCAGATCCAACGCGCTCAGGGTGCACAGACTGATACACACGGGGGAGAGGCCGTACGTGTGTGACCTTTGCGGGCAGAGTTTCACTCAAAGAAGCAGCATGATGGCTCATCGACGCAAACATCCGGGGAGCCACCCACCGCCACCTCCACTGCGGCTCAGCAAACTCGGATGTAACGAGAATGAAAGAGAGCCTGCCGCGGCACAGCAAAAGCCTCCAATCGACAACGCATCTTTCCGATTAGTGGTGGTGGGCACATGGAAGCAACGGGACGCCAGGCCGTTAATAACAAGAATAAGGCAAATTCCACAAACGATCATCGAAGATTTAGATCCTCTAGAAGAATTTGTGACATTTATACACAGCACTGGGAATTCTCAAGAAAACGTCCCCGATACGGCCAGGGATGTACCAGGCTCGTCCACGTCCCGGAACGACGAAACCGAGGTCGATCACGTTCTGGAGAAGATTCGGAACACCTGCCCGTTCTGCGACAAGCGTTTCGACAGCGTGAAGAAAGTGGAGACCCACGTGGCCTGCGTCCACCGACGGCCGTACCAGTGCGACAAGTGCAAGAAGTCCTGGCGCACGTCCGAGGCTTTAGAAGAGCACAAGGTGATCCATCGACCCGACTACTTCTTCGAGTGCGAGGTATGCCACGTGAAGTACAAGAGCGAGTGCAGCCTGAAGAGGCACAAGCTGCGCATGCACAGCGGCCAGGAGTCCAAGTACGTCTGCGAGCACTGCGGCCGCTGCTACAAGCTGAAGATGGACCTGTCCGAGCACGTGAAGAAGATCCACATGACCGAGCCGCAGATCTGCCGGTTCTGCGGCAAGGCGGTGAAGGACGTGAAGGCCCACGAGTGGAAGCATCAGAACCATAAGCGATACCGCGAGGCCAAGTACAACCTTAGCTGCCACTTGTGCCAGAAAAAGTTCTGCCACAGAAGCAGGCTGGACTGCCACTTGAGGCGCCACGAGGAGGGCTTCAGGTGCGAGATGTGCGACAAGGATTTTCTAAGCACAAAAGAGCTAGTGAGGCACAAACAGTACAAGCATGGCCAGACCAAGATCTACACCTGCATCGTCTGCAAAAAGCCCTTCGTCTGCAGCAGCAACTTCTATCAGCACGTGCTGACCCACGCTGGCATACGGCCGTACAAGTGCGACGTCTGCGAGGAGGACTTCACGCAACGCTCCAGCCTCCTCAGGCACAGGAGGCAGCATCCCGGGCCACTGTCGCCGTTGCCATCGACCAACCCTCGGATCACAGAGCTCGCTAAGAGCTATCTGCAGAAGTTACAGAACGACCAGATCGACAAGAGCTGCGTGCTGAACGCTAAATTTTGA
Protein Sequence: MSTIADMSATRTPARPLFVACHGAPFLDHEGKNQPAIQVKSPPISDDEENNHTAPNDLENNYDDFGDESSPDEDDDTLSDNNDDMYMNGGNYRLLSSTVNDTPSPNIVDDDTPSRVGDNGFQEGIDTSVTSVKTVLVPVRDPVTRELKNVLVPVEVKDSTGMNIIKSVLVPVEDEDGLMSYQIKKFVVPIKSQPIVPQKKTKPLPSKNAAKSGIRKKGGKKEAKKEVEKAKEAGEDVTEDKTEESKGDGEPKEAAGADTPKEEVDRILDNVKNSCPYCQKNFEDEKQVDRHVKRIHKKPFRCRVCYNSFVAKESLKDHMKGHDKDALLECPFCHQKYKCMAGLRYHQIRAHSTIEPKYVCDQCGKRFKLKHDLSSHIERSHLTDTYICRFCGKSVRNIKQHEWYHEKSAKKYEYSFSCHLCPTKFRRRTGLDNHLLMHKNSIKCGQCSKGFMCDSELEDHKISHTGEVTYVCKYCRNAYSEKSCLVAHKLLAHGIQQRVPKEFQCNVCSKSFATELSLRKHVTLHSKMFSCSHCDKEFASSHNLKLHIRKHTGERPYECKFCKKSFARSNALRVHRLIHTGERPYVCDLCGQSFTQRSSMMAHRRKHPGSHPPPPPLRLSKLGCNENEREPAAAQQKPPIDNASFRLVVVGTWKQRDARPLITRIRQIPQTIIEDLDPLEEFVTFIHSTGNSQENVPDTARDVPGSSTSRNDETEVDHVLEKIRNTCPFCDKRFDSVKKVETHVACVHRRPYQCDKCKKSWRTSEALEEHKVIHRPDYFFECEVCHVKYKSECSLKRHKLRMHSGQESKYVCEHCGRCYKLKMDLSEHVKKIHMTEPQICRFCGKAVKDVKAHEWKHQNHKRYREAKYNLSCHLCQKKFCHRSRLDCHLRRHEEGFRCEMCDKDFLSTKELVRHKQYKHGQTKIYTCIVCKKPFVCSSNFYQHVLTHAGIRPYKCDVCEEDFTQRSSLLRHRRQHPGPLSPLPSTNPRITELAKSYLQKLQNDQIDKSCVLNAKF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00086570;
90% Identity: iTF_00086570;
80% Identity: -