Basic Information

Insect: Andrena flavipes
Gene Symbol: ZEB2
Assembly: GCA_963971345.1
Location: OZ020482.1:57816617-57821812[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 0.0027 0.34 12.2 0.3 3 23 275 296 274 296 0.96

2 20 0.0012 0.15 13.4 1.1 1 23 300 322 300 322 0.98

3 20 2.6 3.3e+02 2.8 2.7 2 23 329 351 328 351 0.93

4 20 2e-05 0.0026 18.9 2.0 1 23 358 381 358 381 0.97

5 20 1.9 2.4e+02 3.3 0.3 1 12 386 397 386 400 0.87

6 20 0.00027 0.034 15.4 2.4 1 23 416 438 416 438 0.98

7 20 2.7 3.4e+02 2.8 0.8 2 23 443 464 442 464 0.93

8 20 0.012 1.6 10.1 1.1 1 23 470 493 470 493 0.93

9 20 2.2e-05 0.0028 18.8 0.6 1 23 503 525 503 525 0.96

10 20 1.9e-06 0.00024 22.2 5.1 1 23 529 551 529 551 0.98

11 20 6.1e-06 0.00077 20.6 1.1 1 23 557 579 557 579 0.98

12 20 2.9e-07 3.6e-05 24.7 0.7 1 23 585 607 585 607 0.99

13 20 0.12 15 7.0 0.5 2 19 732 749 732 751 0.89

14 20 0.0048 0.61 11.4 0.2 1 23 758 780 758 780 0.96

15 20 0.0074 0.93 10.8 5.1 1 23 786 809 786 809 0.97

16 20 0.00045 0.056 14.7 3.3 1 23 816 839 816 839 0.97

17 20 7.7 9.7e+02 1.3 12.1 2 23 877 898 876 898 0.96

18 20 0.018 2.2 9.6 1.9 1 23 902 925 902 925 0.95

19 20 0.2 25 6.4 2.5 1 23 931 953 931 953 0.96

20 20 3.6e-06 0.00045 21.3 1.3 1 23 959 981 959 981 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	0.0027	0.34	12.2	0.3	3	23	275	296	274	296	0.96
2	20	0.0012	0.15	13.4	1.1	1	23	300	322	300	322	0.98
3	20	2.6	3.3e+02	2.8	2.7	2	23	329	351	328	351	0.93
4	20	2e-05	0.0026	18.9	2.0	1	23	358	381	358	381	0.97
5	20	1.9	2.4e+02	3.3	0.3	1	12	386	397	386	400	0.87
6	20	0.00027	0.034	15.4	2.4	1	23	416	438	416	438	0.98
7	20	2.7	3.4e+02	2.8	0.8	2	23	443	464	442	464	0.93
8	20	0.012	1.6	10.1	1.1	1	23	470	493	470	493	0.93
9	20	2.2e-05	0.0028	18.8	0.6	1	23	503	525	503	525	0.96
10	20	1.9e-06	0.00024	22.2	5.1	1	23	529	551	529	551	0.98
11	20	6.1e-06	0.00077	20.6	1.1	1	23	557	579	557	579	0.98
12	20	2.9e-07	3.6e-05	24.7	0.7	1	23	585	607	585	607	0.99
13	20	0.12	15	7.0	0.5	2	19	732	749	732	751	0.89
14	20	0.0048	0.61	11.4	0.2	1	23	758	780	758	780	0.96
15	20	0.0074	0.93	10.8	5.1	1	23	786	809	786	809	0.97
16	20	0.00045	0.056	14.7	3.3	1	23	816	839	816	839	0.97
17	20	7.7	9.7e+02	1.3	12.1	2	23	877	898	876	898	0.96
18	20	0.018	2.2	9.6	1.9	1	23	902	925	902	925	0.95
19	20	0.2	25	6.4	2.5	1	23	931	953	931	953	0.96
20	20	3.6e-06	0.00045	21.3	1.3	1	23	959	981	959	981	0.99

Sequence Information

Coding Sequence: ATGTCGACGATCGCGGAAATGTCTACTACGCGAACCCCAGCGCGACCACTCTTTGTAGCCTGCCATGGAGTTCCATTTCTGGATCACGAGGGAAAAAGCCAACCGGCGATCCAAGTCAAGTCTCCGCCGATTTCTGACGACGAGGAGCACAACCATACCGCGCCCAACGACCTTGAAAATAACTACGATGATTTTGACGACGAGAGCTCGTCGGACGAGGATGACGATACATTGAGCGACAATAACGATGACATGTACTTGAACGGTGGTAATTGTCGTTTGTTATCGAGCAAGGTTGATGACACTCCCTCCTCGAACTTTGTCGATAACGATACGCCGTCGGGGGTGGGTGACAATAGTTTCCAGGAAGGGATAGATACATCTGTGAACGTGGTGAAAACTGTGCTGGTGCCAGTTCGAGATCCAGTAACCAGGGAACTTAAGAATGTGTGGGTGCCAGTTGAAGTTAAGGATGCAACGGGgatgaatataattaaaagcGTCCTAGTACCGGTCGAGGACGAGGATGGGCTAATGTCGTACCAGATTAAGAAGTTCGTGGTGCCCATCAAGAGCCAGCCGATCGTGCCGCAGAAGAAGATTAAACCATTGCCCAGCAAGAACGCCGCTAAATCAGGAATCAGAAAGAAGGGGGAAGAGAAGAAATTGAAGAAGGAAgtggagaaggagaaggaggcCCGGAAAGATGTGACAGAAGataagaaagaagaaaacaaaGGGGATGATGAGCCAAAGGAAGCTGCTGAAGTAGATACATCGAAGGAGGAAGTGGATAAAATATTGGATAATGTGAAGAACATTTGCCCATATTGCCAGAAGGACTTCGAAGATGAGAAGCAAGTGGACAGACACGTAAAAAGGAATCACAAAAAACCGTTCCGCTGTAGAGTATGCTACAATTCCTTCGTCGCGAAGGAGTCCCTGAAAAACCACATGAAGGGCCACGAGAAGGACGCGTTGCTGGAGTGCCCCTTCTGCCACCAGAAGTACAAATGCATGGCTGGGCTGAGATACCATCAGATCCGCGCGCACAGCACCATAGAGCCAAAATACGTGTGTGACCAGTGCGGTAAGCGGTTTAAATTGAAACACGACCTGAGCTCTCACATCGAGAGGTCCCATCTGACCGACACCTACATCTGCAGGTTCTGCGGCAAGTCTGTGAGGAACATAAAGCAGCACGAATGGTATCACGAGAAGTCGACCAAGAAATACGAATATTCCTTCAGCTGCCACCTTTGCCCGACAAAGTTCAGGCGACGAACTGGCCTCGACAACCATCTGCTGATGCACAAGAACAGCATCAAGTGCGGCCAATGCAGCAGAGGCTTCATGTGCGTCTCCGAGCTGGAGGATCACAAGATCAGTCACACAGGCGAGGTGACGTACATCTGCAAGTATTGCCAGAACGCTTATTCAGAGAAGTCCTGTCTGGTGGCGCACAAACTGCTCGCGCACGGTATACAGCAACGCGTACCTAAGGAGTTCCAGTGCAACGTCTGCAGCAAAAGCTTCGCCACCGAGATAAGCCTGCGCAAGCATGTCACCTTGCACTCCAAGATGTTTTCCTGCTCTCACTGCGACAAGGAGTTCGCCAGCAGCCACAATCTGAAGCTGCACATTCGGAAGCACACCGGCGAAAGACCCTACGAGTGCAAGTTCTGCAAGAAGTCCTTCGCCAGATCCAACGCGCTCAGGGTACACAGACTGATACACACGGGAGAGAGGCCATACGTATGTGACATTTGCGGGCAGAGTTTCACTCAAAGAAGCAGCATGATGGCTCATCGACGCAAACATCCAGGGAGTCACCCACCGCCACCTCCATTGCGGCTCAGCAAACTGGGAATACGCACTGACGAAAATTATCCTTGTTTCAGAAGAGAGCCTGCCGCGGCACAACAAAAACCTCCAAGCGACAACGCATCTTTCCGATTAGTGGTGGTGGGCACATGGAAGCAACGAGACGCCAGGCCGTTAATAACAAGAATAAAGCAAATTCCACAAACGATCATCGAAGATTTAGATCCTCTAGAAGAATTTGTGACATTTATACACAGCACTGGAAATTCTCAAGAAAGCGTCCCCGAAACGGCCAAGGATGTACCAGGATCGTCCACGTCCCGGAACGACGAAACCGAGGTCGATCACGTGCTAGAGAAGATTCGGAATACCTGTCCCTTCTGCGACAAGCATTTCGACAGTGTGAAGAAAGTGGAGACCCACGTGGCCTGCGTCCACCGACGGCCGTACCAGTGCGACAAGTGCAAGAAGTCCTGGCGCACGGCCGAGGCTTTAGAAGAGCACAAGGTGATCCATCGACCCGACTACTTCTTCGAGTGCGAGGTATGCCACGTGAAGTACAAGAGCGAATGCAGCCTGAAGAGGCACAGGCTGCGCATGCACAGCGGCCAGGAGTCCAAGTACGTCTGCGAGCACTGCGGCCGCTGCTACAAGCTGAAGATGGACCTGTCCGAGCACGTGAAAAAGATCCACATGACCGAGCCGCAGATCTGCCGGTTCTGCGGCAAGGCGGTGAAGGACGTGAAGGCCCACGAGTGGAAGCATCAGAACCATAAGCGATACCGCGAGGCCAAGTACAACCTTAGCTGCCACTTGTGCCAGAAAAAGTTCTGCCATAGAAGCAGACTGGACTGCCACTTGAGGCGCCACGAGGAGGGCTTCAGGTGCGAAATGTGCGACAAGGATTTTCTAAGTACAAAAGAGCTGGTGAGGCACAAACAGTACAAGCATGGCCAGACCAAGATCTACACCTGCATCGTCTGCAAAAAGCCCTTCGTCTGCAGCAGCAACTTCTATCAGCACGTGCTGACCCACGCTGGCATACGGCCGTACAAGTGCGACGTCTGCGAGGAGGACTTCACGCAACGCTCTAGCCTCCTGAGGCACAGGAGGCAGCATCCCGGGCCATTGTCGCCGTTACCATCGACCAATCCTCGGATCACTGAACTCGCTAAGAGCTATCTGCAAAAGTTGCAGAACGACCAGATCGACAAGAGCTGCGTGCTGAACGCTAAATTTTGA
Protein Sequence: MSTIAEMSTTRTPARPLFVACHGVPFLDHEGKSQPAIQVKSPPISDDEEHNHTAPNDLENNYDDFDDESSSDEDDDTLSDNNDDMYLNGGNCRLLSSKVDDTPSSNFVDNDTPSGVGDNSFQEGIDTSVNVVKTVLVPVRDPVTRELKNVWVPVEVKDATGMNIIKSVLVPVEDEDGLMSYQIKKFVVPIKSQPIVPQKKIKPLPSKNAAKSGIRKKGEEKKLKKEVEKEKEARKDVTEDKKEENKGDDEPKEAAEVDTSKEEVDKILDNVKNICPYCQKDFEDEKQVDRHVKRNHKKPFRCRVCYNSFVAKESLKNHMKGHEKDALLECPFCHQKYKCMAGLRYHQIRAHSTIEPKYVCDQCGKRFKLKHDLSSHIERSHLTDTYICRFCGKSVRNIKQHEWYHEKSTKKYEYSFSCHLCPTKFRRRTGLDNHLLMHKNSIKCGQCSRGFMCVSELEDHKISHTGEVTYICKYCQNAYSEKSCLVAHKLLAHGIQQRVPKEFQCNVCSKSFATEISLRKHVTLHSKMFSCSHCDKEFASSHNLKLHIRKHTGERPYECKFCKKSFARSNALRVHRLIHTGERPYVCDICGQSFTQRSSMMAHRRKHPGSHPPPPPLRLSKLGIRTDENYPCFRREPAAAQQKPPSDNASFRLVVVGTWKQRDARPLITRIKQIPQTIIEDLDPLEEFVTFIHSTGNSQESVPETAKDVPGSSTSRNDETEVDHVLEKIRNTCPFCDKHFDSVKKVETHVACVHRRPYQCDKCKKSWRTAEALEEHKVIHRPDYFFECEVCHVKYKSECSLKRHRLRMHSGQESKYVCEHCGRCYKLKMDLSEHVKKIHMTEPQICRFCGKAVKDVKAHEWKHQNHKRYREAKYNLSCHLCQKKFCHRSRLDCHLRRHEEGFRCEMCDKDFLSTKELVRHKQYKHGQTKIYTCIVCKKPFVCSSNFYQHVLTHAGIRPYKCDVCEEDFTQRSSLLRHRRQHPGPLSPLPSTNPRITELAKSYLQKLQNDQIDKSCVLNAKF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00088249;
90% Identity: iTF_00088249;
80% Identity: -