Basic Information

Gene Symbol
-
Assembly
GCA_963932275.1
Location
OZ010731.1:6849714-6854335[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.068 9.9 7.9 2.5 1 23 382 404 382 404 0.97
2 18 0.00096 0.14 13.7 0.9 2 23 439 460 438 460 0.98
3 18 0.00027 0.039 15.4 1.2 1 23 618 640 618 640 0.97
4 18 0.0016 0.23 13.0 0.2 2 23 644 665 643 665 0.96
5 18 0.0046 0.66 11.6 3.6 1 23 736 758 736 758 0.97
6 18 0.00047 0.068 14.7 0.7 1 21 764 784 764 788 0.92
7 18 0.022 3.1 9.5 3.2 2 23 867 889 866 889 0.93
8 18 0.0004 0.058 14.9 4.4 1 23 946 968 946 968 0.96
9 18 0.00035 0.051 15.1 0.7 1 20 973 992 973 994 0.94
10 18 0.053 7.6 8.2 0.5 2 23 1005 1026 1005 1026 0.97
11 18 3.6e-05 0.0052 18.2 0.6 2 23 1065 1086 1064 1086 0.97
12 18 3.3e-05 0.0047 18.3 1.6 1 23 1091 1113 1091 1113 0.95
13 18 0.00018 0.027 16.0 2.9 1 23 1119 1141 1119 1141 0.98
14 18 5.8e-06 0.00084 20.7 0.4 1 23 1157 1179 1157 1179 0.95
15 18 4.7e-07 6.8e-05 24.1 0.6 1 23 1185 1207 1185 1207 0.99
16 18 5.1e-05 0.0074 17.7 0.2 1 23 1213 1235 1213 1235 0.97
17 18 0.00019 0.027 15.9 4.1 1 23 1241 1263 1241 1263 0.96
18 18 0.013 1.9 10.1 0.4 1 20 1269 1288 1269 1290 0.89

Sequence Information

Coding Sequence
ATGGACGCCGTCGAAATAAATACGTCCGATTCACCGCAAAACGAAGAAGGCATCGTGCCTACGGTGGAAATATGCCGTGTTTGCCTTCTCGATAATCTAGTGATGCGAGATCTCTTTCTAGAGAACGAGGTTGCTTCTCTTTCAGCAAAGGCCATGAGTTTTGCCAATGTTAAGATGTTACCGGGAGATGGTTTACCAACGCGCGTATGCTGCGTATGCGCGGACAAACTGGAATCCGCGTACGAGTTTAAACTGCAAGTGGAGCAGGCGGATACTGTCCTCAGAGAGAGATTCGTTACCATGAGCATGAAGGAAGAACTGTTCTTCAACGAGGTCGAAGTACATCTCGAGGCAGACGAAGCAAACGACAATATGGGCGAGATGCAGATGGAAAGTCAGTACGCAGCTACCACAGAAGCCCTCGAGTCGATATCTCGAGAAGAGAAGCCATCTCTGTTGAAGGATCAGTTAGCGTTATTGCAGGTGGAAAAGTTGGTGGAACAAGAACAAACTATGAGAGAGCAGGACAACAGTCCGATGTTGGAAGAAGCAGTTGACAGAGCGATGACCACGGGGCAGGTAACGGAAGACTGTCTACACCAGACGGAAGAAACCGTTAAAGTTATTACCGACACGCTCAAGGACGAAGTGGCATTGAAGCACGAGAGCCGCGACGACAACTGCATCGATAGTATCCCGACGGTGGAGCATGATTACATATTGCAGCAGGAATGCATATTGGCAAGCGGGAgccaacaacaacagcaacaacatcAGCTTACTTCCGAAGAATCCTTCTCGCGCGAAGATTGCGTGGAATATGTAAATTTGTTAGTGAAAGCAGCCGACGCGACGAACCGGGAAAACGAAGATGAAAACGACGATGAGCGTATCATCGACGAAAGCCAGAACGAAAATGAAGACGAAAACGAGAATGAGAACGATGCAGAAGGATCGGATGTTATGAAAACGGACGTCAAGATGGAATTGGATTCTCAGTCTTCGAATGAAACGCGAAGAAGCAAACGTAAGCTGGTTCGGCGAAATCCCGAGATAAAGCCGGACTccgacgaagagaattattttgaGAATTTAAATCTAAGCTCGCGGCTTAGGAGGACTCAAACCTCCGATAAGATCTTCTTCATGTGCTACCTCTGCGATAAGGAGTTTCTATCGAAAAACGTCTTGAAGGAGCATATGCATTCTCACGAAGAAGTAAGAAAAGCGTTATCTTTGAAGAAAACAATTGAGAAGCCGCAGAAGAGCGTCTGCAATGTCGCGAAATTGCCACCATCTGGTAAAAGATCGAACAAATGCCCGTATTGCGGCAAGCAGTACATATATATAATCTCATTTAGCAAGCATCTAAAGAAACATGAACGGGAGAAAGAAGAGACGAAGGAGGAGCTGATGCCGTTAGAAATTTCATTTCACGAAGACGATCATAGTTTGGATCTCGACGATTACGAAGCCAAGCGCCACTTTGACTCGGTGTATCGTAAAAGAGCTAGGAGAAAAGAAGCTATCGATAATGCAAGGATGGATCACGAAGAGCTGTCTGACGTCGAGGGGGAAGAGGAAGTGGAAGCGGCGGAGAAGGAGGAGGTGCAgccagaggaggaggaagaggaggaggaggaagatgaGAACGAAGCAGCGGAAGGAGAGGAGGAGGTAGATCAGGTAGAGCCGGAACAGGAGCAGGAACCGGGACCGGAGCAAGAGCAGGAAATTTTGCAGGAGATGAAGGGATATGAAGAAAAGGAAGGAGAAGCGGGAAGAGAAGATGAACGAGACGATAAGCATAAGAGTAACGAAGAACAAGTACGCGGATGTCGCGCAGGAACATTCGTGTGCGATAAATGTTCGGAAAGGTTTTATACGAAACGTGGTTTACGAAAGCACGCGATATCGCACACCACCCTTAAATGCAGCATATGCGAGGAAGAGTTCGACTCACTGGAGGGACTGAGGAATCATCGGGCGAAGCATGTGGTGGAAGGTGTATTGACCGAACAAGATCTGGAAACAGATACAGAACGCTCGGCGAAGACGGGGACGACGGATGGTTATGAAACTAAAGCTAGGACAAAAGTAGAAAGGGGCGAAGAGGAGGCGAGGGAAGAGGCAGAGCTGTCGGGGAGAGAGAAAGTGGTAAAGAAGAACGTCAGACACGCGGTGAGCACGCATTCCGGGATGGACTACAATTGCAAGATGTGTTGTCAGCAATTTGCCAGAAAGGATCTGTTACAGAGGCACATGGAACAACACGAGCGTGTTAAATCCTATAAATGTACACAATGCAATAAATCGTTCGGTAACGAACTTACTTTACGAAATCATCTTATAGCTACTAATCACAAAACTTTCATTCACGGGCAAGAGTACGATCCTAACAAACGTATGAAACGAGTCGCTGCGAAGGCAGCGCAAAAGATTATCGACAAGATTAAAACGGAATACGGTTTAGAAGATTACGATGAGGAAGACGAGAAGGAGGATAAGATTGATCGTACAAATGCTGCGGCTGGAAATTACGGCCGGGGTAAACGAGAGATTTCGTCGCAGAGGAAGCAGAACTGCAAGAAGGAACTGGAATGCCTGAGTTGCAATAGAAAGTGTAGCTCGAGACAATCGCTAATGAAGCACATGGAGCAGCAACACGTGACCGATGAGAAGATGGTGAAGCAAGCAGACAAGCAAAGACAAGCGGCGGAGAAGAAGGAGCGACAGAGGGGCTGCGCGAACGAACGAATGGATAATGATGGGATCAAAGAGGACGACGATTACGATTCGGATTTTGAGAGCGGTTTGGATTGGCCAATGGACAATCACGAGTGTGTAAAGTGCAAGAAAAGGTATAGTACGAAAAAGTCGCTGTTACGGCATCAGTTGTTGCACGAAGAACCAAACTTCGAGTGCGACATTTGCAACGTCAAGTTCTATCGTAAAGACAAGCTGAAAGCACACTACGACAAGTGCTCGGAGAAGAATCCCGACCAAGTGAGGAAGTGCAACATCTGTGGGGATAGCTTTGAAAATAACGAGATCTTACGAGAGCATAGGTCGAAGCATGTGACCGAAGGTATCCTCACGGAGGAAGACCTGAGAGATATCGAGCCGCGACCCGAGGAGAAAAAACCGGGGGAGAAAATCGGCAGGAAAAGGAGAACCGACATCGTAGGTTTAGAATGTACGGAGTGTAATAAGCAGTACACGTCGAGAAAGGGGCTTCTGCGTCATATTCAAGTTCACGAAGGCAAAAAGTACCTTTGCGATATATGCCCGAAGAAATTCTACAGGAGGGAGCATTTGAAGATACACGTAGCAAAGCATAATATGATCAAACCGTACAAATGCACACGCTGCACGAAGCGTTTCATAAAAGAGGAACAGCTGACGAATCATTTGTCGAAGCACGACCGAACGTTTAAGAAGAACAAAGAAACCGACAGCTCGAAGAGATTCCTTTGCGAGATCTGTTCCAAGAGTTTTACCCAATCGACGACATTGATCGCGCATCTTAGAGCTCACAATGGTATCAAACCGTACGTTTGCGAAGTCTGTTCTCGGCCTTTTACAACGAACGCTTACCTAAAGATGCACATGAGGACACACACTCAAGAACGACCATACATTTGTCAGTATTGTTCGCGCGCGTTCGCCAGAGCCGACACGCTTGCTAATCACTTGACCTCGCACACCGGTGAAGCCAAGTATCACTGCAAGTACTGCCCAAAGAACTTCCGCCGCCTCAAGTCCCTCAAAGAGCACGTTTTCATCCACACTGGCCAGAGACCTTACGCTTGCCCAACCTGTGATCGACGCTTCAACAATAATGGAAGTCGATATGCTCATAGTAAAAGGTGTAAACAGAATTTTGTTCAGAATCAGAACCGCGGCCAAGCGTTAACGCAAGTGCAGCAACTGCCTCAAAGTCAACAGCAGAGGGTATTGCAGCAGGCTGCTCTTGGACAAGGGCAAGTGGTTAAAGCGCAGAATATTAAAACTATCACTATCACTAGGCAAGCCGAACCGACCATTACCACCCAACAAGTTACGCAACATCAGGAGATACTGATGCCCTTGATCTTTCCCCTTACCGTTACTGTTGCCGATATCAGCGAAGAAGTTATATTACCAGAGGGAGCTAAGCTATTCACAACATCCTAA
Protein Sequence
MDAVEINTSDSPQNEEGIVPTVEICRVCLLDNLVMRDLFLENEVASLSAKAMSFANVKMLPGDGLPTRVCCVCADKLESAYEFKLQVEQADTVLRERFVTMSMKEELFFNEVEVHLEADEANDNMGEMQMESQYAATTEALESISREEKPSLLKDQLALLQVEKLVEQEQTMREQDNSPMLEEAVDRAMTTGQVTEDCLHQTEETVKVITDTLKDEVALKHESRDDNCIDSIPTVEHDYILQQECILASGSQQQQQQHQLTSEESFSREDCVEYVNLLVKAADATNRENEDENDDERIIDESQNENEDENENENDAEGSDVMKTDVKMELDSQSSNETRRSKRKLVRRNPEIKPDSDEENYFENLNLSSRLRRTQTSDKIFFMCYLCDKEFLSKNVLKEHMHSHEEVRKALSLKKTIEKPQKSVCNVAKLPPSGKRSNKCPYCGKQYIYIISFSKHLKKHEREKEETKEELMPLEISFHEDDHSLDLDDYEAKRHFDSVYRKRARRKEAIDNARMDHEELSDVEGEEEVEAAEKEEVQPEEEEEEEEEDENEAAEGEEEVDQVEPEQEQEPGPEQEQEILQEMKGYEEKEGEAGREDERDDKHKSNEEQVRGCRAGTFVCDKCSERFYTKRGLRKHAISHTTLKCSICEEEFDSLEGLRNHRAKHVVEGVLTEQDLETDTERSAKTGTTDGYETKARTKVERGEEEAREEAELSGREKVVKKNVRHAVSTHSGMDYNCKMCCQQFARKDLLQRHMEQHERVKSYKCTQCNKSFGNELTLRNHLIATNHKTFIHGQEYDPNKRMKRVAAKAAQKIIDKIKTEYGLEDYDEEDEKEDKIDRTNAAAGNYGRGKREISSQRKQNCKKELECLSCNRKCSSRQSLMKHMEQQHVTDEKMVKQADKQRQAAEKKERQRGCANERMDNDGIKEDDDYDSDFESGLDWPMDNHECVKCKKRYSTKKSLLRHQLLHEEPNFECDICNVKFYRKDKLKAHYDKCSEKNPDQVRKCNICGDSFENNEILREHRSKHVTEGILTEEDLRDIEPRPEEKKPGEKIGRKRRTDIVGLECTECNKQYTSRKGLLRHIQVHEGKKYLCDICPKKFYRREHLKIHVAKHNMIKPYKCTRCTKRFIKEEQLTNHLSKHDRTFKKNKETDSSKRFLCEICSKSFTQSTTLIAHLRAHNGIKPYVCEVCSRPFTTNAYLKMHMRTHTQERPYICQYCSRAFARADTLANHLTSHTGEAKYHCKYCPKNFRRLKSLKEHVFIHTGQRPYACPTCDRRFNNNGSRYAHSKRCKQNFVQNQNRGQALTQVQQLPQSQQQRVLQQAALGQGQVVKAQNIKTITITRQAEPTITTQQVTQHQEILMPLIFPLTVTVADISEEVILPEGAKLFTTS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00087365;
90% Identity
iTF_00085607;
80% Identity
-