Aobl032190.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anastrepha obliqua
Gene Symbol
Klhl26
Assembly
GCA_027943255.1
Location
JAPTHQ010000010.1:4478942-4481297[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.7e-33 8.5e-31 107.7 1.2 1 109 51 157 51 158 0.98
2 2 2.9 1.5e+03 0.8 0.0 78 108 158 188 155 190 0.85

Sequence Information

Coding Sequence
ATGGCCGGTGGCGCTGCCTCCATATCACAGGGTGGCCCTGAAAACCGTGCTAACCCAACGTGTGCAGTTTGTGCATCAACAGCATATTCACGTAATGCAAATAATGATAATTTTATGCAAATTATACATTCCGAAGCATTGATGAAGGGTCTAAATGCGTTACGTTGTGCAGAAAAACTATTTGATGTTACCTTACTGGTTGAGGGGCGTACTTTTAAGGCACATCGTGTTGTATTGGCTGCCTGTAGTGATTATTTTTGCGCCATGTTCACTGATGCCATGAGAGAAGCTCACCAGTCTGAAATAAAATTAAATGGCATTAATGCGCATGGCTTAGAATTGCTTCTGGAATATGTCTACACATCCAAGCTGGAGCTAGATCGTAATAATGTGCAGGATGTTTTATCTGTATCGACGCATGTTCAGATGAAGGCAGCTATCGATGCTTGTTCACATTTTCTTGAGTCACAAATCGATTTGGACAACTGTGTTGCGATTGCTGCTCTAGCTGATTTGTATTCACTGGAGCCGTTGAAGAAAAAAGCGTATCGTTACATGTGTTCACGCCTTGATGAATTTGCTCAGACACCGGATCTGCTGAGCCTTACATTGGATCAATTTGAGCACGTTCTCGCATGTAATTATCCAGTGGATTGTTCGGAACAACGAGTTCTTGAAATTGTTTTCGAATACTGTTTGGAGACGGATTTGAAACCAGAGTTAACACGACGTCTTTTCGGAAAGGTACAATTTCACCAAATTGGTGCCTGTGCAATAAATGCAATGAAGTCCAAAGGAAATACGAGTCTCGAATCTAATATTAATGCGCTTACATTGGCCTACTATCGGGTATTGAATGACGAAATGCTAAAGCAAGAGATGGGTAAATTGCGTTTAGCTGATACTTATGCGGATGACTTGCTCTCGGCTGAGGTACTCACAAATACGCGTGGAATGGAATTGGCTTTGGTGAAGATTGGCGGTTTTGAAACAAATGGGTTAACTAATCGCATTAGCTGTTATTTGCCATCCAAAGGCAAATGGGAAAGCCTCACTGTAATACCGCATATCGAACAATGCAACTATGGGACAGCTGTGCTGGGAAATGATTTATACGTTGTAGGTGGCTCGTATGATGTCTGCCTCAAGGAGTATATCCATCCCTTTGGTTTTCGCTATTGCCCCGCCAAAAATAAATGGAAAACGATTGCGCCTATACAAGCGGACCGTTGTCGATTTTCGCTAAATGCTATGGGTAATAACTTTTTGTACGCCGTCGGAGGAGTATGTGAGCTTAATGAGAACGATGGTGGCGCCGAGCTTTGGGCACACGACATGGCTGTTTCGAATTGCGAACGTTACGATGCGAACGCTGATCGTTGGGAGTATCTGCCAGCGCTGTCAGAGAATCGAAGCCAGCATGCCGGCGTCGTTTTAGGAGATCAATTGTATATATCAGGTGGCATTGATCGACACATTGTGCTTGCTTCGCTTTGGCGTTTCGACACTAAATCGAGCAAGTGGCATAAACTGTGTCGGATGCCGACACCACGCGCCGACCATGTTCTGATAGTCTTTGATGGACATATTTATGCTTTTGGTGGTTGGTATGAAGATCCTGTGACAGAAATGCGAGTATTGGCCGATGCGGTGGACGTATATGATACGACCACCGATCAGTGGACGACCGAATCACACAATCCCTTGCCAAAGTACTATACCGGCGTAGCGGCAGTCAAAAGAAAAGTGTATTTTATTGGCGGATTGCTCTCTACGGCTACAATAAATCGTGCCACTTCAGCCGTACAATGTTACGATTTGGATACTAAACAATGGACCTTCAGTTCGGAGTGGGAATACCCGAAAGAAGTTTGGGAAAGTACATGTGCGGCTTTTTATGTGCCACGCGAACGTGATAACGTGAAGTACTATTGGGATGATGCCTAA
Protein Sequence
MAGGAASISQGGPENRANPTCAVCASTAYSRNANNDNFMQIIHSEALMKGLNALRCAEKLFDVTLLVEGRTFKAHRVVLAACSDYFCAMFTDAMREAHQSEIKLNGINAHGLELLLEYVYTSKLELDRNNVQDVLSVSTHVQMKAAIDACSHFLESQIDLDNCVAIAALADLYSLEPLKKKAYRYMCSRLDEFAQTPDLLSLTLDQFEHVLACNYPVDCSEQRVLEIVFEYCLETDLKPELTRRLFGKVQFHQIGACAINAMKSKGNTSLESNINALTLAYYRVLNDEMLKQEMGKLRLADTYADDLLSAEVLTNTRGMELALVKIGGFETNGLTNRISCYLPSKGKWESLTVIPHIEQCNYGTAVLGNDLYVVGGSYDVCLKEYIHPFGFRYCPAKNKWKTIAPIQADRCRFSLNAMGNNFLYAVGGVCELNENDGGAELWAHDMAVSNCERYDANADRWEYLPALSENRSQHAGVVLGDQLYISGGIDRHIVLASLWRFDTKSSKWHKLCRMPTPRADHVLIVFDGHIYAFGGWYEDPVTEMRVLADAVDVYDTTTDQWTTESHNPLPKYYTGVAAVKRKVYFIGGLLSTATINRATSAVQCYDLDTKQWTFSSEWEYPKEVWESTCAAFYVPRERDNVKYYWDDA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00190739;
90% Identity
iTF_01189581; iTF_00081331; iTF_00190739; iTF_00191426; iTF_00193638; iTF_00190026; iTF_01563850; iTF_00192154; iTF_01562976;
80% Identity
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