Basic Information

Insect: Anastrepha obliqua
Gene Symbol: ftz-f1
Assembly: GCA_027943255.1
Location: JAPTHQ010000479.1:419174-433520[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 2 5.6e-14 1.3e-09 39.3 0.5 7 76 1 71 1 95 0.65

2 2 8.3e-74 2e-69 236.4 1.5 157 409 169 414 145 415 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	2	5.6e-14	1.3e-09	39.3	0.5	7	76	1	71	1	95	0.65
2	2	8.3e-74	2e-69	236.4	1.5	157	409	169	414	145	415	0.91

Sequence Information

Coding Sequence: ATGCGTGGTGGTCGCAATAAGTTCGGACCCATGTACAAACGTGATAGGGCGCGAAAACTGCAAATGATGCGACAACGACAACTGGCCTTGCAAGCGCTACGCACTTCAATTGGTTCGGTTGACATGAAGTCGTCACCACTCTCGCCTGGCTACCAACAAGCATATCCGAATATGAGTATAAAGCAAGAAATTCAAATACCTCAGGTGTCCTCTCTCACACAATCACCAGATTCATCGCCCAGTCCCATTGCCATTGCGCTGGGGCAGGTCAATACAAGTGGTGGTGTGATATCTCCGCCTATGAATGGTGGTGGCGGTAGCGCTGGCGGTGGTGGTGGTGGTGTCAGCGGCAATGGTGGCAACACCGGCGCCAACAATAGCAACAGCAATAACACCAGCGATGGACTCAACCGCGGTGGTAGTGGCAATTGTCACGACACTGGAAATGGATCTCTGCAAAATGCGTCCGAATCGAAACTGTGCTTCGACTCCGGCACGCATCCTTCAAGCACTGCTGATTCCATAATCGAGCCGCTCAGGGTTTCACCAATGATACGTGACTTTGTGCAATCAATAGATGATCGGGAATGGCAGACACAACTCTTTGCGTTACTACAGAAACAATCCTACAATCAAGTGGAAGTTGATCTCTTCGAGCTGATGTGCAAAGTGTTGGATCAGAATCTGTTCTCTCAAGTGGATTGGGCAAGAAACACTGTCTTCTTCAAGGATCTTAAGGTTGATGACCAAATGAAATTGCTTCAGCATTCGTGGTCCGACATGCTGGTGTTAGACCATTTGCATCAGCGAATACACAACGGCCTACCCGATGAAACGCAATTAAATAACGGTCAAGTATTCAATCTGCTCTGGCTAGGCCTGCTTGGCGTACCCCAATTGGCGGACTATTTCAATGAACTCCAAAGTCGTTTGCAAGATCTTAAGTTCGATATGGGGGATTATGTGTGTATGAAATTCCTAATCCTACTCAATCCAGATGTACGTGGCATTGTCAATAAGAAGACCGTTTTGGAGGGTCAAGAGAATGTGCAAGCAGCGCTCTTGGACTACACGCTCACCTGTTATCCATCAGTGACGGATAAATTTCGGAGGTTGCTTAGCATACTGCCTGATATCCATGCGATGGCTTCACGAGGCGAAGACCATCTCTATTCGAAACATTGTGCCGGTAGTGCACCCACGCAGACACTACTAATGGAAATGCTGCATGCTAAAAGAAAAGCATAA
Protein Sequence: MRGGRNKFGPMYKRDRARKLQMMRQRQLALQALRTSIGSVDMKSSPLSPGYQQAYPNMSIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNTSGGVISPPMNGGGGSAGGGGGGVSGNGGNTGANNSNSNNTSDGLNRGGSGNCHDTGNGSLQNASESKLCFDSGTHPSSTADSIIEPLRVSPMIRDFVQSIDDREWQTQLFALLQKQSYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHQRIHNGLPDETQLNNGQVFNLLWLGLLGVPQLADYFNELQSRLQDLKFDMGDYVCMKFLILLNPDVRGIVNKKTVLEGQENVQAALLDYTLTCYPSVTDKFRRLLSILPDIHAMASRGEDHLYSKHCAGSAPTQTLLMEMLHAKRKA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01357984;
90% Identity: iTF_00083027;
80% Identity: iTF_00083027;