Basic Information

Insect: Anastrepha ludens
Gene Symbol: Zfy1
Assembly: GCA_028408465.1
Location: JAPVRI010079982.1:3309-5480[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 4.6e-06 0.00077 21.2 2.2 1 23 214 236 214 236 0.98

2 11 5.3e-07 9e-05 24.1 1.6 1 23 242 265 242 265 0.97

3 11 1.6e-05 0.0027 19.5 0.4 1 23 271 293 271 293 0.98

4 11 5.4e-05 0.0091 17.8 2.2 1 23 299 321 299 322 0.95

5 11 1.8e-07 3.1e-05 25.6 0.3 1 23 329 351 329 351 0.98

6 11 0.0013 0.23 13.4 1.0 1 23 357 380 357 380 0.96

7 11 0.046 7.8 8.6 0.1 1 23 386 407 386 407 0.95

8 11 0.00011 0.018 16.9 2.0 1 23 413 435 413 435 0.98

9 11 6.9e-05 0.012 17.5 0.7 1 23 441 463 441 463 0.99

10 11 0.023 3.8 9.6 1.5 1 23 469 494 469 494 0.95

11 11 0.0001 0.017 16.9 0.1 1 21 500 520 500 521 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	4.6e-06	0.00077	21.2	2.2	1	23	214	236	214	236	0.98
2	11	5.3e-07	9e-05	24.1	1.6	1	23	242	265	242	265	0.97
3	11	1.6e-05	0.0027	19.5	0.4	1	23	271	293	271	293	0.98
4	11	5.4e-05	0.0091	17.8	2.2	1	23	299	321	299	322	0.95
5	11	1.8e-07	3.1e-05	25.6	0.3	1	23	329	351	329	351	0.98
6	11	0.0013	0.23	13.4	1.0	1	23	357	380	357	380	0.96
7	11	0.046	7.8	8.6	0.1	1	23	386	407	386	407	0.95
8	11	0.00011	0.018	16.9	2.0	1	23	413	435	413	435	0.98
9	11	6.9e-05	0.012	17.5	0.7	1	23	441	463	441	463	0.99
10	11	0.023	3.8	9.6	1.5	1	23	469	494	469	494	0.95
11	11	0.0001	0.017	16.9	0.1	1	21	500	520	500	521	0.96

Sequence Information

Coding Sequence: ATGATGCACAGTCGTCGCTCTGTCTCCAAAGAAGATGTCGGGTCTATGCACACCGACAGCGGCATTTCGCTGTCCTCGCCGCCTGCCGCGTGCGCAGAGCTCTGCGACGGTGGTGAGACACAACAGTCATCGGCAGCTACCACGAAGAAGCTGCTGCGGCGTCGTGCTAGTGATGTAAAAGTAACAAAGAGGGCGTGCAGAAGCAAACAAGTGGCATATGCAAAGTCTCCAAAGCGGAAGAAGCAGAAAATCGGTCATTCAGTGCCAAGCGAAAATAATGCAGCGGCACCCGGAAGTAATTCAGTCATATCAGCCAAACAACTGGCGGGCTTGGATGTGCAGGCGCACCAGGAGGGCGCCGATCTAGCGCATGCTGTCGATTCAGCAGCTAGCATAACAGTCGCAATTGTCAATTCAACAGAGGATATAGAAAATCCTGTAACTCCTGCTGCGGCGTCTTCAGAGAAGTCCATTTCGATCGCCGATTCTGCATACTCCGAAACCGATGCCACACAATCAGCCGCCGACTTATCGGATATAACGCATTCAGCATGCGATTCCGCGCTCACAACCGGAGAATTGGCTTCCGTGGCCACAGCATTACCAGCCACCTCAGCCAATAAACGCACACGTCAATTATACATTTGCCATGTTTGCTCCAAGCAATTTCGCGGCAAAAACGATTTGAGGCGTCACATGCTCATCCATTCGGACGAACGTCCATACAAGTGCGAGCAATGCGGCAAGTGCTACAGGCAGGCGGTCAATCTCAGGAATCACATCACTTCCGCACACGAGAGTCATCGGCAGTTCTCGTGTCCGCAATGCCCGAAAATGTTCGCGTTGAAGGGCCGCTTGCGGCTGCATATGCGACTGCACTCCGGCGAGAAGCCATACGCGTGCACACAGTGTGAGAAGCGCTTCGCTCGTGGCGGTCATTTACAACAACACATCATTAGCCATCACAAAGCTAGCGCCAAGCAGTATATCTGCGAGAAATGCTCCACTGCTTTCTCCACGCCTTCTAATTTGCGCGCGCACATGGAGCGCCATGAAAACGGGCCTGATCACTATTGCGAGATATGCAAGGAACACTTCCCCAATGAGCCAGTACTCAGAGCGCACATCAACAAACTGCACTACAAGTTGGGCCAGTTCGATTGCGAGATCTGCAAGAAGACCATCGAGGATGAAGCGCTGGCCAAGCACATGAAGATGCATACGAATGTCAAGACACATGTCTGCGAAGTTTGCAAGGCGTACTTTATGCAGAAATCCCAGTACAATGTGCACATGCGCATGCATACTGGCGAGCGGCCGTACCAGTGCCGGATTTGTTGGCAAACTTACGCTTACTCAAGCGTACTGAAGCTGCACATACGTAAGCACACAGGTGAGAAACCGTTTCAGTGCTTGCTGTGCAAGGACGTGGTCGCTTTCTCACAGCTGGCACACTTCAAGACGCACATGAAGAAAATTCATAAGCAAACCAATCCATATATGTGCGAGGGTTGTCAACAGTTCTTTAAGGTCAAAGCGGAACTTCAGGCGCATATGCAACAATGTGGCAGCTGCAACATTGATGTGGAGCAACAGAATGCCAAAAATAATGACCTACAAACACTCTCGCATTTACGTTTCCTCATGGCGTTGCTGTTGAAGAAGATTTCATCGCCGCAGAAATTGCAGCAATTAGGCTATGAGAAGCGTCTGATCGACAATGTTGTGGTGGCATCACTCAAGTTGGCCAATCGAAAGGCTTGCGAGGATCAGACGCTGTCGGCAATCGAACGCATGCGCAAGAATGTGGAAGAGTTTCTCAATTGGATTGTGCCTACAAAGGCGATGGAAACATTTCGTCAAGAGCAGCAATCCGTGGAGAGTATACTGGACAAAATTGTTACCATGTACATGAAGCACAAATAA
Protein Sequence: MMHSRRSVSKEDVGSMHTDSGISLSSPPAACAELCDGGETQQSSAATTKKLLRRRASDVKVTKRACRSKQVAYAKSPKRKKQKIGHSVPSENNAAAPGSNSVISAKQLAGLDVQAHQEGADLAHAVDSAASITVAIVNSTEDIENPVTPAAASSEKSISIADSAYSETDATQSAADLSDITHSACDSALTTGELASVATALPATSANKRTRQLYICHVCSKQFRGKNDLRRHMLIHSDERPYKCEQCGKCYRQAVNLRNHITSAHESHRQFSCPQCPKMFALKGRLRLHMRLHSGEKPYACTQCEKRFARGGHLQQHIISHHKASAKQYICEKCSTAFSTPSNLRAHMERHENGPDHYCEICKEHFPNEPVLRAHINKLHYKLGQFDCEICKKTIEDEALAKHMKMHTNVKTHVCEVCKAYFMQKSQYNVHMRMHTGERPYQCRICWQTYAYSSVLKLHIRKHTGEKPFQCLLCKDVVAFSQLAHFKTHMKKIHKQTNPYMCEGCQQFFKVKAELQAHMQQCGSCNIDVEQQNAKNNDLQTLSHLRFLMALLLKKISSPQKLQQLGYEKRLIDNVVVASLKLANRKACEDQTLSAIERMRKNVEEFLNWIVPTKAMETFRQEQQSVESILDKIVTMYMKHK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01189748;
90% Identity: iTF_00083255;
80% Identity: -