Basic Information

Insect: Anastrepha fraterculus
Gene Symbol: Hr39
Assembly: GCA_037575425.1
Location: JAYXIM010029492.1:424391-432652[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.97 1.5e+04 -3.7 0.2 152 180 46 73 21 77 0.44

2 3 3 4.5e+04 -11.0 13.0 54 148 235 363 209 400 0.47

3 3 4.1e-96 6.1e-92 310.5 6.6 1 408 542 915 542 915 0.83

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.97	1.5e+04	-3.7	0.2	152	180	46	73	21	77	0.44
2	3	3	4.5e+04	-11.0	13.0	54	148	235	363	209	400	0.47
3	3	4.1e-96	6.1e-92	310.5	6.6	1	408	542	915	542	915	0.83

Sequence Information

Coding Sequence: ATGTCCTCCACAAAAGCAGAGAGCGCCGCTGGCGCCAATCCCTCAGCGGCTGCCTTTGGCTCAACGCTAGCGGGTAATGCATTCCAGCTGCCCGTGAATATGCATAACCATGCTCAAATAACTTCAAATGGCAGTAGCTGTCACAGTACGAATGGCACAACTACAACGACCACAACAACAACGCGCAACAATATATCCGTCACGAATATCAAATGTGAAATGGATGAGGGCATTGCGGCATCGTTCATGCCCAACGGCAATATAGTGCCTGTCATAGCTGCGACGGGCGCTGCCAGCTTCTATAACGGTGCCAGCAGTGggagtggtggtggtggtggtgttggtATACGTATACCTGTCACGAAGGCGGAAGATTCCGATTCGGAGACTGAATTGACGAACATTGAGAATTTAAAGGTGACGCGACGCGCGCACACAAATGCGGACAGCAGTACGCCTGGCAGCAGTGCTGCTATTGGCGGTAGCTCTAGTACCACAAATCACAACAAGAATGGACCCCGTCCCATGTCCTGGGAAGGTGAACTCTCCGAAACGGAGACGACTGAAACGGAGCTCATGGAAACGGAAAATTCGTTAGGTAGTAGCGGCATATTGCCGAACAGTTTAAACACCAGTATTGGCGGCATCGGTGTGGCGGTGATTAAGAGTGAGGCGACCACCACAACACCTGGACACACGGTGGCGCCTACGCCTACACATCCCATTAAACCCGAGCAAATGGAGCAAATTTCCGTGGAGGTGCATAGCGCTACGGCGGGTGTTGGTCCATCGCGCAGTGGTTtgggcagcagcagcagcgcggGTAGTCTATATCCCACGCCACACACAAAACTAGCGCCTACGCAAAGTGATCCCATAAATTTGAAATACGAACCCGATGCTTCCGCTACGGGGATCATTTCAGCTGGCGCTAATGTAAACTCGCCACTTTTAACGCGCAACAAATCAGCCACGCTGCCATTGCCCGCTAATCCCAGCCCCGATTCTGCCATACATTCCGTCTATACGCACAGCTCACCGTCCCAATCGCCGTTGACGTCGCGTCATGCGCCCTACACCCCATCGCTTAGTCGAAACAATAGCGACGCATCACACAGTTCTTGCTACTCCTACAGCTCAGAGTTTAGTCCGACACATTCACCCATACAGGGCAGACATGCGCCACCAGCTCCTGCACTCTACGGTAGCTTCAATGGCTCGTTGCATCATTCGGTGCTCTACCGGCCCATTTCGGTGGACAGCGGTGGTGGTGGCAATGGCAATTCCGGTGGAAACTGTAATGCGGAGGTGCAAAATCTTAGCATGGACACGAAGGTTTCGCCACTCAATATAGGTCTTGAAGGATTGCCTGCCTCGCCGGCTGGTATTTCGCGTCAGCAACTCATCAATTCACCCTGTCCCATTTGTGGCGATAAAATTTCCGGCTTCCATTATGGTATTTTCTCGTGCGAATCTTGTAAGGGCTTTTTCAAGCGCACTGTCCAGAATCGCAAAAATTATGTGTGCGTACGTGGCGGTCCTTGTCCGGTGAGCATTTCGACGCGTAAGAAATGTCCTGCCTGCCGTTTCGAAAAATGTCTGCAGAAGGGCATGAAGCTCGAAGCCATACGAGAGGATCGTACGCGTGGCGGCCGCTCCACGTACCAGTGCTCGTATACGTTGCCCAATTCGATGCTAAGTCCGTTATTGAGTCCCGAGCAGCAGGGTGTTGCTGCAGCAGTAGCTGCGGCTGCAGCAGCAGCGGCCagtcaacagcaacaacagggACGACTTGGTACGCAAATGGCGCATGCAATGACCGCACAGCAGCAGCCCACATTGAACGGGCTGACAGCGGGACTAAGTGTGGGACAAACAGTAATCAAGTCGGAGCAGTGCGATGACGGAGGTGCATCGGCGCGTGCAACAAACATTCCAACGCTACTGCAGGAAATCATGGATGTTGAACATCTGTGGCAGTATAATGAAGCCGAATTGGCGCGTCTCAATCAACCGATCTCCTCATCGTCTTCTTCATCTTCCAATGCGTCTTCGTCCTCATCGTCCACTGCGGTTAGTGGCGGTGGTGCCACTGTCAATCCACAAATGACAAACCCTTTGCTGGCAAGTGCTGGCTTCGGTAACGGTGAAAATGCCAATCCCGACCTGATTGCGCATCTGTGCAATGTGGCGGATCATCGGCTGTACAAGATCGTCAAATGGTGCAAGAGTTTGCCACTCTTCAAGCATATTTCGatcgATGATCAAATTTGCCTACTGATCAATTCGTGGTGTGAATTGCTGCTCTTCTCTTGCTGCTATCGCTCAATCGATACGCCGGGCGAGATCAAAATGTCACAAGGCAAGAAGATTAGCTTAGCGCAGGCGAAATCAAGTGGCTTACAGGCCTGCATTGAACGAATGTTGAACCTGACAGAAAACTTGAGACGCCTACGAGTTGATCGCTACGAATATGTTGCCATGAAAGTGATTGTGCTGCTGCAGTCagACACCAGCGAATTACACGAGCCCGTCAAGGTGCGCGAGTGCCAGGAGAAGGCGTTGCAAGCCTTGCAGGCCTACACGCTTGCGCACTACCCAGATACGCCGTCCAAATTTGGTGAGTTGCTGCTGCGCATACCAGACTTACAAAAGACATGCCAGCTTGGCAAGGAGATGCTCACCATAAAATCACGTGACGGTGGCGATTTCAATTTACTTATGGAGCTGCTGCGTGGAGAACATTGA
Protein Sequence: MSSTKAESAAGANPSAAAFGSTLAGNAFQLPVNMHNHAQITSNGSSCHSTNGTTTTTTTTTRNNISVTNIKCEMDEGIAASFMPNGNIVPVIAATGAASFYNGASSGSGGGGGVGIRIPVTKAEDSDSETELTNIENLKVTRRAHTNADSSTPGSSAAIGGSSSTTNHNKNGPRPMSWEGELSETETTETELMETENSLGSSGILPNSLNTSIGGIGVAVIKSEATTTTPGHTVAPTPTHPIKPEQMEQISVEVHSATAGVGPSRSGLGSSSSAGSLYPTPHTKLAPTQSDPINLKYEPDASATGIISAGANVNSPLLTRNKSATLPLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQGRHAPPAPALYGSFNGSLHHSVLYRPISVDSGGGGNGNSGGNCNAEVQNLSMDTKVSPLNIGLEGLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCPVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPEQQGVAAAVAAAAAAAASQQQQQGRLGTQMAHAMTAQQQPTLNGLTAGLSVGQTVIKSEQCDDGGASARATNIPTLLQEIMDVEHLWQYNEAELARLNQPISSSSSSSSNASSSSSSTAVSGGGATVNPQMTNPLLASAGFGNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKHISIDDQICLLINSWCELLLFSCCYRSIDTPGEIKMSQGKKISLAQAKSSGLQACIERMLNLTENLRRLRVDRYEYVAMKVIVLLQSDTSELHEPVKVRECQEKALQALQAYTLAHYPDTPSKFGELLLRIPDLQKTCQLGKEMLTIKSRDGGDFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00082980;
90% Identity: iTF_00082980;
80% Identity: iTF_00081319;