Adis035961.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anastatus disparis
Gene Symbol
KLHL10
Assembly
GCA_017163975.1
Location
JAFFSR010000226.1:8687405-8695285[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 9.5e-26 2.9e-23 84.7 0.3 2 109 52 158 51 159 0.93

Sequence Information

Coding Sequence
ATGGAAATTGACGAGAATAACAATAGTTTGGCTGCCACGAGTAGTAGTAACGAAGATCTAACGGAGGCTGAAAAATCTTGCGTCAATTCAAAACGTTTACTTGCCGATCAAAGCAATGGCCGATGCATGAGTACTCAAGCAATGCAATCACTTTACGATTTAAgacaaaataatttactttgCGATGCTGTATTGAGACTCGAGGATGGCGGAGTATTTCCAATACACCGGGCTATATTATCGGCATGCAGCAGATACTTCAGAACCCTATTCACAACAACGTTACATTCGAAGGACAAAACGGATTTCCTTTTACCGAATGTCAGCAGTAAAATCATGAATCTGCTACTGGAGTACGCATATTTAAGAACGTTGGATGTAAGGCAAGACAACGTTTGTCAACTATTGATCAGCGCCGATTATTTAAGTATCTTCGGAGTTTTAGAGCTTTGTTGCAATTTTCTACAATCAAATTTTTCGCCGGAAAATTGCATTGGTATCATGATTTTTGCACGAGAACATTTTTGCAGGGGTCTTGAAAAGGAAGCTCGTCGATACATCCTGAGAAATTTCGTTCAGgTTGCCGAACGTTGCACTGAAATTCTTGCGTTACCGATCGAAGAATTAACGGCCTTAATAGGCGAGGACGAGCTCAATGTTAAAAACGAGGAAACAGTATGGGAATTAATAATCCGTTGGATAAATCACGACGTTGAAAATCGCAAGGGTCATATAGTAGAATTGATGCGCAACATACGTCTTGGTTTACTGGATAcgcaattttttttggaaaacgTAAAAGACCATTTGTACGTCGTTGGAAATGAATCGTGTCGGCCAATTGTCATCGagacattaaaatttctttacgATCTTGAAATGATAACGCAAAAGGACGGCGAAGTACCAACGCCAGAAATAGCCAGACCAAGAGTACCGCATGAAATATTATTTGCTATCGGTGGTTGGAGCGGTACCGCTGCTACTAACTTGATCGAGACTTATGATACTAGGGCCGATCGTTGGGTCAAGATCGAAGAAGTTGATCCCAATGGACCAAGAGCTTATCATGGTACAGCGGTTGTTGGCTATAACATTTACGTCATCGGCGGTTTCGATGGCATCGACTTTTTCAATAGCTGTCGATGTTTCAACGCAGTGACAAAAACTTGGCGGGAAGTCGCGCCAATGAATGCCAGAAggtcTTACGTAAGTGTAGCAGTTTTGAATGACATTGTTTACGCAATGGGTGGTTTTGATGGCTATCATCGTCAAAATACTGCCGAACGTTACGACTATCGACGAAATCAATGGTCTCTGATTGCTTCTATGAATGTTCAAAGATCGGATGCCAGTGCTACAACGTTAAATGGCAAAATTTACATAACTGGTGGTTTCAATGGTCGTGAGTGCATAAGCTCGGCTGAGGTTTATGATCCGCAAACTAATCAATGGACCATGATAGCACCAATGTGGTCGCGTAGAAGTGGCGTATCTTGTATTGCTTATCATGGTTCTATTTATGCTATAggAGGTTTTAATGGTATATCACGAATGTGCTGCGGAGAAAAGTATAATCCAGCTACCAATACCTGGACGCGTATACCTGATATGTATAACCCACGAAGTAATTTTGCTATTGAAATCATTGACGATATGATATTCGCTATTGGAGGTTTCAATGGTGTTAGCACTACGTATCAGGTCGAGTGTTATGATGAGAAAACTGATGAGTGGTACGAAGCAACAGATATGAACATGTATCGATCAGCTTTATCTGCCTGTGTAATCATGGGTTTGCCAAACGTTTACGATTACATTCACAAACATCGTGAGCGTTTAATGGAAGAAAAACGACAAAAGCTTCTTGCGCTCGAAGTTCAACGAatacaacagcagcagcaacaacaacagcaacttAACTCTCCTGTAGCTAATCGCGGTGCTCATCAGCTCGTAGTACTGACAAATCAACAACAACAAAATCCACGACCACACCAATCaagacaataa
Protein Sequence
MEIDENNNSLAATSSSNEDLTEAEKSCVNSKRLLADQSNGRCMSTQAMQSLYDLRQNNLLCDAVLRLEDGGVFPIHRAILSACSRYFRTLFTTTLHSKDKTDFLLPNVSSKIMNLLLEYAYLRTLDVRQDNVCQLLISADYLSIFGVLELCCNFLQSNFSPENCIGIMIFAREHFCRGLEKEARRYILRNFVQVAERCTEILALPIEELTALIGEDELNVKNEETVWELIIRWINHDVENRKGHIVELMRNIRLGLLDTQFFLENVKDHLYVVGNESCRPIVIETLKFLYDLEMITQKDGEVPTPEIARPRVPHEILFAIGGWSGTAATNLIETYDTRADRWVKIEEVDPNGPRAYHGTAVVGYNIYVIGGFDGIDFFNSCRCFNAVTKTWREVAPMNARRSYVSVAVLNDIVYAMGGFDGYHRQNTAERYDYRRNQWSLIASMNVQRSDASATTLNGKIYITGGFNGRECISSAEVYDPQTNQWTMIAPMWSRRSGVSCIAYHGSIYAIGGFNGISRMCCGEKYNPATNTWTRIPDMYNPRSNFAIEIIDDMIFAIGGFNGVSTTYQVECYDEKTDEWYEATDMNMYRSALSACVIMGLPNVYDYIHKHRERLMEEKRQKLLALEVQRIQQQQQQQQQLNSPVANRGAHQLVVLTNQQQQNPRPHQSRQ*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01469793; iTF_01465471; iTF_01111081; iTF_01113543; iTF_01112747; iTF_01110256; iTF_00464079; iTF_00708611; iTF_01219177; iTF_00708075; iTF_00305716; iTF_01216886; iTF_01524120; iTF_00304539; iTF_00845341; iTF_00968959; iTF_00969750; iTF_00693082; iTF_00309600; iTF_00714518;
90% Identity
-
80% Identity
-