Basic Information

Gene Symbol
-
Assembly
GCA_963576865.1
Location
OY756416.1:2240559-2244805[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 1.9 2e+02 3.8 0.1 5 20 185 200 183 202 0.91
2 13 0.00046 0.048 15.2 0.1 2 23 218 239 217 239 0.97
3 13 0.0051 0.53 11.9 4.2 1 21 247 267 247 268 0.94
4 13 0.011 1.1 10.9 2.8 2 23 299 320 298 320 0.97
5 13 0.00019 0.02 16.5 4.0 1 23 328 350 328 350 0.98
6 13 0.00028 0.029 15.9 2.2 1 23 358 381 358 381 0.95
7 13 1.1e-06 0.00011 23.5 4.5 1 23 405 427 405 427 0.98
8 13 2.4e-07 2.5e-05 25.5 0.9 1 23 433 455 433 455 0.96
9 13 6.5e-06 0.00067 21.1 0.3 1 23 461 483 461 483 0.99
10 13 7e-07 7.3e-05 24.1 0.7 1 23 489 511 489 511 0.98
11 13 3.1e-05 0.0033 18.9 0.6 1 23 517 539 517 539 0.98
12 13 6.1e-05 0.0063 18.0 2.1 1 21 545 565 545 567 0.96
13 13 4.2e-06 0.00043 21.7 0.1 1 23 573 595 573 595 0.98

Sequence Information

Coding Sequence
ATGGATATCACAACAAACATAAATCTAGAAAAAATCTGCAGGATTTGCTTGCTGGAATCCCCGCATATGGTGTCATTATCGACCAAAATGGAGGGGAACAATCGAACACTGTACGACGTCTTGCTATTTGTTCTAAATAACAATGTTTCTGTGGGCGAAAAGTTTCCCAAACAAATTTGTGGTGACTGTGAGATGTTTTTGTTCCGTATTGAGGAGTTTAAAAGACGGTGCAATGAATCTGAGAACATTTTGAAGGAACTTGTTGATGCTACTCAGTCAGGACCATCCCAAGTTATTAAGTTAGAATCGACGACTAAAAAGGAGAAACAGACAACATTTGATCACTTTTTAGAGCTAAATCCAGTTAATGTACTAGATACCTTGAAAGAAGACGCGATGGCAATCGAATTTGATCCTGCAAAAGCTGAAACTAAAGTTGGCGTGAAGGAGTCTATTAAGGAAGAGTTTTCAGATTTCTCTGACGATATGGATGATAGGACTTTTGGGGAAAATAGTGAAAATATATCGGAGGATAAGAATCTATACAACTGTCAGTGTGGTGAAGGATTttctaagttaaataaatatcagattCACTTGGATAGTAAAGAATGTTCTAAAAAAGTCAAACAGTTATTGTTGATACCAGTCAAATGTGCACAGTGTGGTttggtatttaaaaatgaagaagaaatTAAAGAACATGTTAAAACTCATGCCAAACTAAATTCTAAGTATTTTGAATgttcattttgtttaaaaaaattctcaaaGAAATGTAATCTTCAAtcacatttagaaaaaaaagtttgtactaAAGTTACAGTTAAACAAGAAATGAAACACAAAGGGAAAGATAAATCTAAAGCGAGTTCATTAATGTTAATGCCTATCAAATGTGAGCAATGTAACATTCTGTTTAAAAACATGAAATCGTTTAAAACTCACAAACAAACTCATGTTAAAAGCGTTCCAGAGTTCTTCCAATGTTCTCAATGCATGAGGAAGTTTAAGAAAAAGTCATCGCTTATTACACACATGAAAAATCACGAAGAAAAAGACAATTTGAAGTATACTTGTGATATTTGTAAACGCGAGTTCAAATATCAGGCACATCTTGACAACCACAATCAATCGGAGCACAGTAAAAGAAAAGGTCTCATCCGTTTAGAAGTGTTTCCGTTGGACACAAATAAGTTAAATGATAAGAAACATCAATGCAAACTTTGTACTAAATCATTCAGTATGCAGTCAACCTTGACGGATCATATGAGAACACATACTGGGGAGAAGCCATTTCTGTGTTCGGTATGCGGTCGAGGTTTTACGCAGAAGACTAATCTGGCCCAGCACATGAGAAGGCATTTGGGATTGAAGCCGTTTAAATGTACTGAATGTGAACGAGGGTTCGTCTCCAAGGGCGAGCTAGACGCACACCTGCGCAAGCACTCCGGCGCGCACCCGTTCGTGTGCGACGAGTGCGGGAACGGGTTCACCACGTCCAGCTCGCTGCGCAAGCACAAGCGAGTCCACACGGGCGAGCGGCCGTACGCTTGCGACTTGTGCCCTATGAAGTTTCGTGTCTCTGGTACTCTCAAAAGCCACCGCCGCACGCACACCGGCGAGAAGCCCTACCAGTGCTCGTACTGCGAGAAGGCCTTCGTGCAGCGCCAGGACCTGGTCTCCCACATCCGCTGCCACACCGGCGAGCGGCCCTTCGTGTGCGCGCTGTGCGGCCAGGCCTTCCGGAAGCCCTCCGCCCTGAAGGCGCACGCCAAGACGCACAAGCAGCCGCAGCCTGGACCGATGATGGCTTTGCAGGGGACCGGGTGA
Protein Sequence
MDITTNINLEKICRICLLESPHMVSLSTKMEGNNRTLYDVLLFVLNNNVSVGEKFPKQICGDCEMFLFRIEEFKRRCNESENILKELVDATQSGPSQVIKLESTTKKEKQTTFDHFLELNPVNVLDTLKEDAMAIEFDPAKAETKVGVKESIKEEFSDFSDDMDDRTFGENSENISEDKNLYNCQCGEGFSKLNKYQIHLDSKECSKKVKQLLLIPVKCAQCGLVFKNEEEIKEHVKTHAKLNSKYFECSFCLKKFSKKCNLQSHLEKKVCTKVTVKQEMKHKGKDKSKASSLMLMPIKCEQCNILFKNMKSFKTHKQTHVKSVPEFFQCSQCMRKFKKKSSLITHMKNHEEKDNLKYTCDICKREFKYQAHLDNHNQSEHSKRKGLIRLEVFPLDTNKLNDKKHQCKLCTKSFSMQSTLTDHMRTHTGEKPFLCSVCGRGFTQKTNLAQHMRRHLGLKPFKCTECERGFVSKGELDAHLRKHSGAHPFVCDECGNGFTTSSSLRKHKRVHTGERPYACDLCPMKFRVSGTLKSHRRTHTGEKPYQCSYCEKAFVQRQDLVSHIRCHTGERPFVCALCGQAFRKPSALKAHAKTHKQPQPGPMMALQGTG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00074761; iTF_00075773;
90% Identity
iTF_00075773;
80% Identity
-