Basic Information

Gene Symbol
-
Assembly
GCA_950371115.1
Location
OX493351.1:1146759-1150713[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 2.9e-05 0.0028 19.0 3.1 1 23 439 461 439 461 0.98
2 17 0.97 94 4.8 0.2 2 23 465 486 464 486 0.93
3 17 4.7 4.5e+02 2.6 5.2 3 23 493 514 491 514 0.93
4 17 0.012 1.1 10.8 0.2 2 23 569 591 568 591 0.96
5 17 0.005 0.49 12.0 4.3 1 23 597 620 597 620 0.95
6 17 0.028 2.7 9.7 0.4 1 21 624 644 624 645 0.93
7 17 0.0014 0.14 13.7 0.5 1 23 653 676 653 676 0.96
8 17 0.059 5.7 8.6 2.5 1 23 681 704 681 704 0.95
9 17 0.00051 0.049 15.1 0.4 2 23 717 738 716 738 0.96
10 17 1.5 1.5e+02 4.2 4.2 1 23 744 766 744 766 0.97
11 17 0.00098 0.095 14.2 1.6 1 23 802 824 802 824 0.97
12 17 0.48 46 5.8 0.1 2 23 829 850 828 850 0.93
13 17 0.031 3 9.5 0.5 2 23 868 890 867 890 0.96
14 17 0.00022 0.021 16.3 1.9 1 23 896 918 896 918 0.98
15 17 0.031 3 9.5 8.8 2 23 925 946 924 946 0.96
16 17 0.043 4.2 9.0 0.8 1 23 952 975 952 975 0.89
17 17 1.9 1.8e+02 3.9 1.1 3 23 982 1003 981 1003 0.95

Sequence Information

Coding Sequence
atggaAGAAGGAAACATCTCATTGAAAACAGCTAAAGAAAAGAAAGACTTCAACAATATACAGCACCTGAAACAGAAACTATCTTTGATATGTCAAGCACAGAGATTCTGCGGCATTTGTCTGGAGAGCACGGAGAAACTGTGGTCCGTTAACACGGAGTTTGATATTGCAGTCAGACAGTTGACacataaaaaacttttaaaggaTATAATCGATTACATTCTTAATAATGAGAGTCAGCAAATCCTTGCCAGTATCTACCTGTGCAGTCACTGTACGGAGAAATCAATTCAATCATACCTATTCATTTATAATGCCAAACAACTTTCAAAAATAATCTACGAATGTGTGAATGAACTATACTCCAAAACTGTTGATGTTCAAAATCAATTGCAAAAATTCCAAGACTATCAAAATGCTAATGTGGTTATTGTTTTAGAACAAGAACACGAAATGAGCAATTATACCGATATTGGTAAAACAACCGAGATTGTCGCTAAAGAAACCTCAAAGAACGAGGAAACAATTTCGGATTCATCTATAAGAAATTCAGAGGAGAAACCAGATAATTGTAAAACGGAAGTAATAAGACATATAGATAGAGCAGAAAAACAATCAAAAGATGGTGAAAATGTCTTAAAAGAAGAAGTAAGAAATGAAGACATAGaaataacatatttaaatagcAATTTTTTACCACCAGAAATTGAGACAGACAAGGTACATTTACAAACTAAAACTGAATTTGTCACACCAACAAAGATAAAGAAAATCATCCCAACTCTAACGCTGAATAAGGAAGTAACTAGTGAAAACGTAGAAATAACGTATTTAGATGAGCAATTTCAATCACAGGACATCAAGACAGAAAAAGTAAGAACTGAACTTGTCAGTACAATGCCAAAGAACGAAATCATCCAAATTCCAACCACGAATAAGGATGCTCATGaagatataataataacatatttacAAGAAGACTTTCAACCGTCAGAAATGAAGACTGTTAGCGATTATCCAGAAGCTAAAACTGAACTTGTCACAGTACAAACAATCCCGACTATAACCGTAAACGACGAAGTTACCAATAAAGACATagaaataacatattttgaagAGGATTTTCTAACATCAGAAATTGAGTCTGATATGGATTATACACACGAAACAAAAGTTAgtccaaagaaaaaaaagaaaattatgccAACAACATTTAAGTGTTTAAGGTGTAGAGAAATACTCCCGTCTTACAAAAGTTGTAAGGACCACAAAAAAATTTGCAAGAAGCAAAAACCTGATGCAAGCATGTCAATGTTCAAGTGCAAAGTGTGCAATGAAAAATTTATCACTCAACGATCTTTGAACACTCATTATAAGTCTCATGCTAAAACAAAATGCAAAGTCTGTCAATTTATAGTCCCTGAAGATGATTTGCAAGAACATATGAAAATTAATCATGAAGAGTATGCTCATCTTTGTAAATTATGCAATTTCTTCTGCTTTACTGCTGAGGGATTAAAAACTCATACAGAAAAGAATCACAGCGGCCCTGAATGTGCGTTGTGTTTAAAAAGAGTGAAAGGAAAAGATTTGAAGAGGCACAGATGCAAATTCAATTGTTTAGAATGTTTGGACAACATCTGCATACATTATAAATACCTAGTTTCATACAAACAACAAGTGCTGAATAATATTACCAAAATAAAATGCGTTGACTGTGATTATGTCTGCCCTAGACGGGAAGCATTACTAGGTCATGTTAACAGAGAACATTTGGATCATCACCCGTTTACTTGTGACTATTGCAAACAGCAATTTTACTCTCGAACTACCTTGAGATATcacataaacttttttcataaggaGAGACATATTTGCGAGTTTTGTGACCAAGAGTTCACGAATAAGACCATTTTAGAAAACCATATAAAACTTTGCCAGTGTATCGAGAAAGACTACAAATGTGATAATTGCAAGAGTTCCTTTGAAACGTTGGAAGAATTAGCGAACCATGTTAAATTGCGTCATGCTGAAGAGGCTTTCAATTGTAATTTGTGTAAGAAGAAATTCTTGAACAGTTTAAAGTTGCAAGATCACATGTTTAAAGTGCACAGTGGGATTCAGATCAAGAGAAAAGGGTCTCTTTTAATTTGTCCAATATGCGACGAGAAATGTGAGAACAAAAGGCTATTGCTTGAGCATATAAAAATACACGGACCAGACGCAAGGTTTCCTTGCAAAGAATGCCATGTAGACTTTGATTGTATTAAAAAACTACACGCTCATATAAGAATACACTATGACGATGTAATACAATGTGTTGACTGCAAGAAAGTATTGACAAAGACATTCTTTCCTCACCACATGGTGTATTGCAATGTTGGCCGTGAAGCAAAAGAGGTTTTCACATGCGAAACTTGTGGTAAGACTTTTCCCAATGAAGTTCAGTTTAAGTTCCACAGAAAAGTCCATTTAGAGAAAGTACCGTGCCCTATATGCAAAAAGCCAACAAAGCCAGTTTATATGAAGGGTCATATCAAACGGTTACATAACAAGTCCAGAAAACCCAAAATTCCTAAGCCAaagtatgtaaaaaatatgaaatgcgAATGGTGCGGACATCTTGTATCTCGGTACGGTGAATTGGAGACTCATGTCAACCGATTTCACTTGAAAATAAAGCCGTATCAATGCAACTACTGCCAGAAGTCATTTTTCGGGAAAGAGCGTTTAAGAGACCACCTAGTAACCCACACAACAGCTAAGAACTGTTATTGCAGTATCTGTAACCAGAAATGCGAGAACAAAGCGTGCCTTAAACTCCACATGAGAAAACATACTGGTGTTAAACCTTATACTTGCGAAATTTGCGGTGACAGTTTTAGAACTTCAAGTATCATGAATACTCATAAAGTGAAGAAACATTCAGAGAGGACAGTGGCTTGCCCTCTTTGCGATGCAATGTTTCACTTGACGAGGGAAATGAGGAGTCACTTTAAAAAGGTACATTGGAAGCAGAAACATAAGAAATTCGACCCTAGAGATGTTAAAGAATTAAGTCCTGCGTTTTATCATCTATTTGAAGATGGTAGGATTACCAAAGTAGAAGGTGAAGAGTTGTATATCTCTTCgaagtttaatgaaaaatattaa
Protein Sequence
MEEGNISLKTAKEKKDFNNIQHLKQKLSLICQAQRFCGICLESTEKLWSVNTEFDIAVRQLTHKKLLKDIIDYILNNESQQILASIYLCSHCTEKSIQSYLFIYNAKQLSKIIYECVNELYSKTVDVQNQLQKFQDYQNANVVIVLEQEHEMSNYTDIGKTTEIVAKETSKNEETISDSSIRNSEEKPDNCKTEVIRHIDRAEKQSKDGENVLKEEVRNEDIEITYLNSNFLPPEIETDKVHLQTKTEFVTPTKIKKIIPTLTLNKEVTSENVEITYLDEQFQSQDIKTEKVRTELVSTMPKNEIIQIPTTNKDAHEDIIITYLQEDFQPSEMKTVSDYPEAKTELVTVQTIPTITVNDEVTNKDIEITYFEEDFLTSEIESDMDYTHETKVSPKKKKKIMPTTFKCLRCREILPSYKSCKDHKKICKKQKPDASMSMFKCKVCNEKFITQRSLNTHYKSHAKTKCKVCQFIVPEDDLQEHMKINHEEYAHLCKLCNFFCFTAEGLKTHTEKNHSGPECALCLKRVKGKDLKRHRCKFNCLECLDNICIHYKYLVSYKQQVLNNITKIKCVDCDYVCPRREALLGHVNREHLDHHPFTCDYCKQQFYSRTTLRYHINFFHKERHICEFCDQEFTNKTILENHIKLCQCIEKDYKCDNCKSSFETLEELANHVKLRHAEEAFNCNLCKKKFLNSLKLQDHMFKVHSGIQIKRKGSLLICPICDEKCENKRLLLEHIKIHGPDARFPCKECHVDFDCIKKLHAHIRIHYDDVIQCVDCKKVLTKTFFPHHMVYCNVGREAKEVFTCETCGKTFPNEVQFKFHRKVHLEKVPCPICKKPTKPVYMKGHIKRLHNKSRKPKIPKPKYVKNMKCEWCGHLVSRYGELETHVNRFHLKIKPYQCNYCQKSFFGKERLRDHLVTHTTAKNCYCSICNQKCENKACLKLHMRKHTGVKPYTCEICGDSFRTSSIMNTHKVKKHSERTVACPLCDAMFHLTREMRSHFKKVHWKQKHKKFDPRDVKELSPAFYHLFEDGRITKVEGEELYISSKFNEKY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00076977;
90% Identity
-
80% Identity
-