Afus033583.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anania fuscalis
Gene Symbol
egg
Assembly
GCA_950371115.1
Location
OX493355.1:3219991-3273858[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 0.86 4.6e+03 -1.7 0.0 17 38 1946 1983 1944 1985 0.83
2 2 7.8e-14 4.2e-10 40.1 0.0 4 75 2015 2079 2012 2081 0.90

Sequence Information

Coding Sequence
ATGAGTTCAGGCCAAGGAGATACCGCCACTGCTAAGGCAGACGACGATACAGAATTAAATTCACCCAATGAACATGATAAACTGGCGTCTAAAGATCAGGTGGATCACATTTCAGAATCATCACTTGACAAAGTAACAAGGCCTTTTCAGGAGCTCGTAACTGAAGATCCCAGTAATAAAACTGATTCAGGCTTTAAAGACAACGTCCTTACCGATATTATCGACAAAACTAAGTCGGGTTCGGATAATACAGATGATAATAGCGATGATGACTTAGAATTGAAGtgggatgatgatgaaactgatgaacaaaatatttcactgTTGGAAAATATTCAGAAAATTAGTGAAACCGTGTCTGACATTGCTAAACCAATGGTGGCAGACATAGATGATGCAAATCTCAGCAGCACTGATGCTATTGGAGAAAAAACAGATGAAAttgatgaaaacaaattacttgAAAGTTCACCTTCGAACAACGAAGACACTAATCTATCTAGCACTTCAGATTTAGCTGAAACTAATTTACCCATAAGCAAAATTGATGAAAATGAAGGTATTGCTGCAGGTTTCGAagatgtcattgatgaaaataaaCTTCTGGAAGGTCCAGAGTCTGATACTGTTGATGAAGCTAAATTGCTTGAAATTTCTGATGAAAACAAAGAGGATTCACTTTCAAATGATGATTTGAGTCAAATTGACCTAAATTCTTTAGCAAAAACAGTTGTGGATACTTCAGATAATGTAGCTTTGTCAGACATTGCTAAAGAAACTTCTTGCTTAGAGTCTCTAAACTTAATTTCTTCAACTCAAATATGTGACAAAAAACCTCAATTGGCCCCTACTAAATCAGTTAATActgaaaatatggaaaaagcCATCATTCATTTAGAATCAACATCACCCATACAAGATAAGTCACATCTGGCCCTATCCCAAAGCTCTCCCAAAGATTCTGTGATGGATACAACTCTCGATATAAACACAGAACATGGACTTAACAAACCAGACATGATGCTGGAAATACCAACTCAAGAGATCATTGAACTGATAGATGACACTGATATTTCAGCATCTGAAACatataatgatgataaaatggATGTTGACGATGCTAATGACAGTTCTAAACTAGATACTTCTGAATATATTGATAAAGTAGGAGAAGGAAAATCTACCTTAGAAGTGAAAGCTGATGCAGTTATTCTAAAACCAGCTGATGTGTTTAGGGCATTAAACACACAAACACCAAGTAAAGATGCGAGTAATGAAGCTAACAAAATGGAAGATGTTTCAGAAGATGATTGGTGTGAAATTGAAAGGAGGTTGGAAGGATTTGAGGACTCTATTAATGAAGAATCACAGCCGATTGAACAATCTACAATTACAGATTCCGAAAATGTTCAAGAGACAAAATCAAAGGATGATGTGTCTTCAACACTAAAAGACAAACCATTATCAGAAGAAGCAGCGACTGAGACTTTGCCATTGACAAATGCACAAAAACTGGTTATAGAATCTGAAAACAAAGAATTGTTGAAAACACTACAGGATACCTCAAAGCTAGACTGTACTGAAGATGAAATATCAACTACAATGGATGTTGAAGACGAAATATTGGCAAACCCTGTCATTGAAGGTAAATCTATAGAACCTTCCATAGAATCAACTCTTGATATAGTTAAAGATGATATTCCACCAAAAACAGATTTAGAATCTAACTTAGACATAACtcaatcaaacaataaaaacgaGGTAAATTCAGATCTAGAACATCAGCACCTAGAATCTCTTAAACCTGATACTAAAGCCTCTAAACCTATGTCACCTTTAAAGTTAATAGAGGAAATGGAAGCCCATGAAGGAAAATCAAAAGCACAGTTGGAATCATCAAAACCAGATACTAAAGAATCAACAATAGATTTGTCACCACCTGTTGATGAAAAGACAACAGAAtcattaaaaacattaacaGTTCATGAATTGGCTGAAGTAAGAGCCTCAGAAATTATAGTGCAAAAATCTGATCAGACAGATAAAGTTGCAATATCAGAACCAATAGAAATCCAAGTAACAACAAATCAAAGTAATGATAAAGTCCTTTCATCAACACATGATGATATACCTGCTGAAGCAAAGTCACTATTACAGCTAATTAATGGTGAACTTAAATCTGAAACTTCTATAACTGCTATTGAAGACAAAGACAAATCAAAACCCACAGATAAAATTGAGAACAAACTAGGAGAGGAATTGATGGAGGTGGATGTTGAATCTTTAACATCTAAGTTACACAGTGAAGATGATGCTGTAGATATTGCGTCAACTCTTATTGATGTACCTCTGTCAGTTACTAAGTCAGTTGATGATAAAATTTACACTCCATCAACTGAAATTGAGACTGCAATTCATGACCAAAGATCAACAAATGGAGCTCAAGCAACCTTACTAAAACTCCCATCAACTACAAAATCTGATAGTGAAGGTCCTTCGATAAAATTATCTGGTGATATTGAAGTAACACCATCAATATCAGTTAATGACAACCCATCAACTTTAAAACACGACAGTCTGGCCCAATCTGCACCAAAGCCATTTGATGATATTAAAGTCCAACCATCAACACCAAAGGTACCTGGTAATATTGAAGTACAGCCATCAACTCCAAAAATATCAGATGATATTGTGGCAAAGCCAGTAACTTTAAAGATATCAGATGATATTGAAGCACAGCCATCAAGTTCAAAGATACCCGATGACATTGAAGTACAACCTTCAACTTCAAAGATACCCGATGACATTGAAGCACAGCCATCAAGTTTAAAGACACCCAATGACATTGAAGTACAACCTTCAACTTCAAAGACACCCGATGACATTGAAGTACAACCATCAAGTTCAAAGATACTGGATGACATTGAAGTACAACCTTCAACTTCAAAGATACCTGATGATATTGAACCACAGCCATCAACATCATCAGAAGTTCCTATCCCATCTGTAGAACCAATAAATACAGACCCAGATTCAGCAGATGATGTTGCGGAGACATCAGACAGTCTGGGGCTGTTGGCGGAGTCATCTAGGGTGATGGAAGATGATGAAGAGcaagatgaagatgatgatgctgatgccgatgctgacgatgatgatgattacgatCCAGAAGATGAAAGCAGCAATCAAATGACAGCAGAACATTCGGAAGACTCGAACGCTCCCCACTCTGAGACAGATCAGGCGAAAGATGAGAAAGAGATGGAGATAGAATCCCCTCTAGAGGAAAAGGGAGAGGATGAGTTCAGTTTCACTGCAGAAGAGAAGGACGGAGCTATCGCGGATGACAAGGATGTCAGTATGGATATAGATGAAGAAGTAGTGCAAGATGTCATCGAAGTAACAGCAGAACAGGTCGGCAATGAGGCGATCCCAGACGATGTCGAGGCATCGGACACCGTTGCAGAAACTAAGGAGGAAGATAAAgaAAAACCAAAGGAAACAGTCATAGAAAAGGTAGAACCGTCAGACGCGTCGGCCAAAGAGTCCAAATCGATATCCATGTTGAGGAAACTACTCGCCAAAGATGAAGAAGCGAAAACAAGTGACAAGAAACTAGGGTATAAGGAACCGCACGTACTTAACATCGTCGACTTAGAGGGGAGCTCGTCGGAAGACGACATACAAGAAGTGAAGAAGGATGCCGCCAAAGACGGAACCCTCATAACCTTCGACGGTTTCAAGATCACCATACCGAGTAGCGTGGACGTGAGTAGCGTCCCGACGGTACCAGAGGTCGCTAGTGAGGAAACTGTCACTACTGACGATAAGAACGGTGAAAATACGGCGAAAACTGACAGTAAGCCGGCAGAAGATAAACCCAAACCGAAGTTCAGCCTGGAAATATTCAGTCTAGATTCTGATGAAGAGGAGAACGCTAGTGCACCTGCTACAGAACAAAAGCCACTCGCAGCAGACGATGTGGATAAAGCCAAGCATACGAACAAATGCGTCAATATCGCTTGTACATCATCCGGGAAGGTACCGTGCTATCCCGCGGATGCTGCTACAGTATCATACTATGACGCAGCTAAGCGTCGGAAGCCTCTTGTATGTCAAGCGTGTGCGGATATCGTTGTTAATAGGACTCAGTGTTATAAGGCTCATAATGCATCAACGAAGTCTGCAGATGCAGCTACCATAGCATTTTATTACGTGACGGAAGGAGCTGGAATGTTAAGGTCTCATGCAGATGATGCTACTATATCATACTATGATTCGGCTAAGCGTCGGAAGCCTCTTGTTTGTCAAGCGTGTGCGGATATCGTTGTTAAGAGTACTCAGCGTTTAGTGAACGGCATAAAAGATATCACACCGCTCCTTGAGTTGGACACTTGCAAGCTGTCTTCGGAATTGGTCGAGATATCTGACTCAGAGTCTGAAGACGAGACAGATACATCAGATGAGCCACGAGAGACGATAGGAGAGATTGGAGCTAGTTTCTTAGAAGCAAATCTAGCTAAGATGATCAACGAAACGTGGACCAAATTCTGTTTGGACTCTAGATTGGCCGAAGCTCAAGACGACCTTGATAAGGAAATGGAGAAATTGGATGCTGAAAGCAAAGAAATCGACGCGATGCTGACGGAATGCCAAGTGGCGACAGACAAACTGAGGAACGATTTGTACGCGACGTTCGAGCAACGGAGACGCGACCTCGGTGCGATTACCATATACGATACTCCTGTTACTAAATATTCGTGTGTAGAAAAAGATCAAGCTCCAACTGAAAGTGCTCCTGAGACTCGAGCAAAACGCCGAATGTCGTCCGCTACGGAAACTCCAGCTAAGAGGCCCGCCATACCGCTGGGCTACACTCCTATAAACAGCGACACTGCTCAGGCGCAGgACAACAAAGTGCCAACAGTTGAAAATACGAAAGCAGACGatgatAAAGACATATCAGTGCTGAAAGTGTCAGCAGAATCGGCCCCCTCTGACCTGCCCCCTCCCGGCGAGTTAACCCGCCCCCCGCTGCGCGTGGGCATGTGCGTGTACGCGATGCGCAACGCGTTCGGCAGCTGGCTGCGCACGCGCGTGCTGGAGGTTAACGGGAAGAGCGCCGTGCTGGGGATGTCGCAGACGTTTACCGTGTGCCGCATCAAGTACGAGCACAAGCCCAAGGGCTCCACCAAGCTGGCCCCCGCCCGCTGCCTGGCCTACTCCGAGCCCGCGACTGTGAGACTCACTATCGGTACAAGAATCATAGCGCTCTTCAAAGACTCGCAGAATCCTTTGAAGAAAGACGCCTTCTACTCCGGCATCATATCTGAAGTGCCCAATCCAGTAAATAACTAcagGTACCTAGTGTTCTTCGACGACGGCTACGCGCAGTACGTACAACATCGCGACACACGCGTCGTTTGCGAGTCCTCCTCTCTTGTATGGGAAGAGGTTCACCCGTTCTCGCGAGAATTCGTTCGGGAATACCTCCTGGCGTATCCGGAGCGACCCATGGTGCGACTACACGCCGGACAGAGCCTGAAAACTGAGTGGAACGGAAAATGGTGGACCTCCCGCGTCATCCAAGTAGATGCCTCCCTCGTCCAAGTGCACTTCGAGGAAGACAACAGGACGGAGTGGATCTACCGCGGCTCCACCAGGCTGGCGCCGCTGTTCCTGGAGTTGCAGGCGGCCGAGCGGCACCGCGCCAGACCGATGCCGAGGACCAAGGCGCAGCCCAGGctAAATATGCCTTACGTGGAGTACACTCGTTCGGACGAGCAGAACAAGTCGGAACCACCAGCACCGCAGGCACCACCTATCAGCGAAAAAGAGATTCGTCAACGAGCGGTCGCTAAAAAGTCGACCGCCCTGCCGCCCGCGCCCAACTTCCTGCCGCCGATCTCGGACAGCGTCACCAGCAGAGTTGTGTATTACACTCCCAAGAATGCGGTGAAACCGTACAAGATGACCCCGCACACCTGCGGGCCGCACTGCAAGCGGAAAGACGTACTCGCGTTGAAAGATCTACGCACATACAATCCCCTGGCGAAGCCACTACTCAGCGGATGGGAGCGACAAATAGTCCGCTACAAGGGGCACAAGGAGGTGATGTACCGCGCCCCGTGCGGGCGGCGCCTGCGCAGCCTGCGCGAGCTGCACCACTACCTGCGCGTGGTGCAGGCCGACATGGCCGTCGACTTGTTCGACTTCACGCCGCACACGCACTGCCTCGCCGAGTTCGTGCTGAACAAGTGCCTCGTCGGGAAGAAGGACCTGTCCCACGGCAAAGAAAACGTCCCAGTCCCCTGCGTGAACTACTACGACGAGTCACTACCGGAGTTCTGTTCCTACAACACCGAGCGCACCCCCACCGCTGGGGTACCGCTCAACCTTGACCCCGCCTTCCTGTGCGGCTGCGACTGCACCGACGACTGCGAGGTCAGTGCTCAGTGCTCAGTGCTCACTACAACACTGAGCGTCCCCCACCGCTGGGCGTCCCCCACCGCTGGGGTACCGCTCAACCTTGACCCCGCCTTCCTGTGCGGCTGCGACTGCACCGACGACTGCGAGGTCAGTGCTCAGTGCTCAGTGCTCACTACAACACTGAGCGTCCCCCACCGCTGGGTACCGCTCAACCTTGACCCCGCCTTCCTGTGCGGCTGCGACTGCACCGACGACTGCGAGGTCAGTGCTCAGTGCTCAGTGCTCACTACAACACTGAGCGTCCCCCACCGCTGGGTACCGCTCAACCTTGACCCCGCCTTCCTGTGCGGCTGCGACTGCACCGACGACTGCGAGGTCAGTGCTCAGTGCTCAGTGCTCACTACAACACTGAGCGTCCCCCACCGCTGGGCGTCCCCCACCGCTGGGGTCCCGCTCAACCTTGACCCCGCCTTCCTGTGCGGCTGCGACTGCACCGACGACTGCGAGGTCAGTGCTCAGTGCTCAGTGCTCACTACAACACTGAGCGTCCCCCACCGCTGGGTACCGCTCAACCTTGACCCCGCCTTCCTGTGCGGCTGCGACTGCACCGACGACTGCGAGGACAAGTCAAAATGCGCCTGCTGGCAGATGACGCTAGAGGGCGCTCGTACTATCGGCCTGAATGGACCCAACGTCGGCTACAAGTACAAGCGGTTACCGGAGCCGCTACCCTCTGGTATATACGAGTGTAACTCTAGGTGCAAATGTAAACATACGTGCCTCAACCGAGTCGCACAACATCCTCTACAATTGAAACTTCAGGTGTTCAAGACATTGAACCGCGGCTGGGGTATACGGGCCCTGAACGACATTCCCAAGGGCTCGTTCCTCTGCGTGTATGCTGGGAACCTGCTCACTGACGCTACAGCTAATATGGACGGTCTCAACGAAGGCGACGAGTATCTAGCCGAGCTGGACTACATAGAGGTAGTGGAGCAGATGAAGGAAGGCTTCGAAGAGGATATACCTGAAGCAGACAAGCGGCTCGACAAGCAGAAGGGCGCTACTCAGGCGTCGTCCGAGTCTGAGGAGTCTTCATCAGAAGAGGAGAGCGGGCCGTCGAAGGACGAGCAGGAGGACGGGGACTTCTGTCCCGGGTACATCGGCATGGGCGTCTCAGAGTTCAGcaAAAGACTACGGAAGCGAGACAAGAGTAAGAAGAAGAACAAacaagatggcggcgccaaggAGAAAGAGAAGGACGGCGACAAACCCGGCGACGACTGCATCACCATCAGTGATGACGAGGAAGTTCGTGAGCCATCTAGTTTTATGGCGAAGGCCGGGATGGGGAAAGAGTTTATATCCAAATAtagGTCGGTTCGTTCGTACTTCGGTAAAGATGAGGCTTGTTACATTATGGACGCTAAGGTTCAGGGCAACATCGGCAGATACTTGAATCACTCGTGCCAACCGAACGTGTTCGTCCAGAACGTATTCGTAGACACGCACGACCCCCGTTTCCCGTGGGTGGCTTTCTTCGCGCTGTCGCACATCAAGGCCGGCAGCGAGCTCACCTGGAACTACAACTACGACGTGGGTTCGGTGCCCGGGAAGGTTCTTTACTGCTACTGCGGCGCGCCCAACTGCAGGGGCAGACTGCTCTAA
Protein Sequence
MSSGQGDTATAKADDDTELNSPNEHDKLASKDQVDHISESSLDKVTRPFQELVTEDPSNKTDSGFKDNVLTDIIDKTKSGSDNTDDNSDDDLELKWDDDETDEQNISLLENIQKISETVSDIAKPMVADIDDANLSSTDAIGEKTDEIDENKLLESSPSNNEDTNLSSTSDLAETNLPISKIDENEGIAAGFEDVIDENKLLEGPESDTVDEAKLLEISDENKEDSLSNDDLSQIDLNSLAKTVVDTSDNVALSDIAKETSCLESLNLISSTQICDKKPQLAPTKSVNTENMEKAIIHLESTSPIQDKSHLALSQSSPKDSVMDTTLDINTEHGLNKPDMMLEIPTQEIIELIDDTDISASETYNDDKMDVDDANDSSKLDTSEYIDKVGEGKSTLEVKADAVILKPADVFRALNTQTPSKDASNEANKMEDVSEDDWCEIERRLEGFEDSINEESQPIEQSTITDSENVQETKSKDDVSSTLKDKPLSEEAATETLPLTNAQKLVIESENKELLKTLQDTSKLDCTEDEISTTMDVEDEILANPVIEGKSIEPSIESTLDIVKDDIPPKTDLESNLDITQSNNKNEVNSDLEHQHLESLKPDTKASKPMSPLKLIEEMEAHEGKSKAQLESSKPDTKESTIDLSPPVDEKTTESLKTLTVHELAEVRASEIIVQKSDQTDKVAISEPIEIQVTTNQSNDKVLSSTHDDIPAEAKSLLQLINGELKSETSITAIEDKDKSKPTDKIENKLGEELMEVDVESLTSKLHSEDDAVDIASTLIDVPLSVTKSVDDKIYTPSTEIETAIHDQRSTNGAQATLLKLPSTTKSDSEGPSIKLSGDIEVTPSISVNDNPSTLKHDSLAQSAPKPFDDIKVQPSTPKVPGNIEVQPSTPKISDDIVAKPVTLKISDDIEAQPSSSKIPDDIEVQPSTSKIPDDIEAQPSSLKTPNDIEVQPSTSKTPDDIEVQPSSSKILDDIEVQPSTSKIPDDIEPQPSTSSEVPIPSVEPINTDPDSADDVAETSDSLGLLAESSRVMEDDEEQDEDDDADADADDDDDYDPEDESSNQMTAEHSEDSNAPHSETDQAKDEKEMEIESPLEEKGEDEFSFTAEEKDGAIADDKDVSMDIDEEVVQDVIEVTAEQVGNEAIPDDVEASDTVAETKEEDKEKPKETVIEKVEPSDASAKESKSISMLRKLLAKDEEAKTSDKKLGYKEPHVLNIVDLEGSSSEDDIQEVKKDAAKDGTLITFDGFKITIPSSVDVSSVPTVPEVASEETVTTDDKNGENTAKTDSKPAEDKPKPKFSLEIFSLDSDEEENASAPATEQKPLAADDVDKAKHTNKCVNIACTSSGKVPCYPADAATVSYYDAAKRRKPLVCQACADIVVNRTQCYKAHNASTKSADAATIAFYYVTEGAGMLRSHADDATISYYDSAKRRKPLVCQACADIVVKSTQRLVNGIKDITPLLELDTCKLSSELVEISDSESEDETDTSDEPRETIGEIGASFLEANLAKMINETWTKFCLDSRLAEAQDDLDKEMEKLDAESKEIDAMLTECQVATDKLRNDLYATFEQRRRDLGAITIYDTPVTKYSCVEKDQAPTESAPETRAKRRMSSATETPAKRPAIPLGYTPINSDTAQAQDNKVPTVENTKADDDKDISVLKVSAESAPSDLPPPGELTRPPLRVGMCVYAMRNAFGSWLRTRVLEVNGKSAVLGMSQTFTVCRIKYEHKPKGSTKLAPARCLAYSEPATVRLTIGTRIIALFKDSQNPLKKDAFYSGIISEVPNPVNNYRYLVFFDDGYAQYVQHRDTRVVCESSSLVWEEVHPFSREFVREYLLAYPERPMVRLHAGQSLKTEWNGKWWTSRVIQVDASLVQVHFEEDNRTEWIYRGSTRLAPLFLELQAAERHRARPMPRTKAQPRLNMPYVEYTRSDEQNKSEPPAPQAPPISEKEIRQRAVAKKSTALPPAPNFLPPISDSVTSRVVYYTPKNAVKPYKMTPHTCGPHCKRKDVLALKDLRTYNPLAKPLLSGWERQIVRYKGHKEVMYRAPCGRRLRSLRELHHYLRVVQADMAVDLFDFTPHTHCLAEFVLNKCLVGKKDLSHGKENVPVPCVNYYDESLPEFCSYNTERTPTAGVPLNLDPAFLCGCDCTDDCEVSAQCSVLTTTLSVPHRWASPTAGVPLNLDPAFLCGCDCTDDCEVSAQCSVLTTTLSVPHRWVPLNLDPAFLCGCDCTDDCEVSAQCSVLTTTLSVPHRWVPLNLDPAFLCGCDCTDDCEVSAQCSVLTTTLSVPHRWASPTAGVPLNLDPAFLCGCDCTDDCEVSAQCSVLTTTLSVPHRWVPLNLDPAFLCGCDCTDDCEDKSKCACWQMTLEGARTIGLNGPNVGYKYKRLPEPLPSGIYECNSRCKCKHTCLNRVAQHPLQLKLQVFKTLNRGWGIRALNDIPKGSFLCVYAGNLLTDATANMDGLNEGDEYLAELDYIEVVEQMKEGFEEDIPEADKRLDKQKGATQASSESEESSSEEESGPSKDEQEDGDFCPGYIGMGVSEFSKRLRKRDKSKKKNKQDGGAKEKEKDGDKPGDDCITISDDEEVREPSSFMAKAGMGKEFISKYRSVRSYFGKDEACYIMDAKVQGNIGRYLNHSCQPNVFVQNVFVDTHDPRFPWVAFFALSHIKAGSELTWNYNYDVGSVPGKVLYCYCGAPNCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-