g5917.t1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Amphipyra tragopoginis
Gene Symbol
Klhl10
Assembly
GCA_905220435.1
Location
HG992008.1:20493988-20501157[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1.2e-27 2.5e-25 87.7 0.0 2 108 56 162 55 164 0.92

Sequence Information

Coding Sequence
ATGGAATTTAATTCGAAACAtcgaaaattatcaaaaaataaaaattctgttCGTACTCCTTCATCCTCGAAACCCAGATTAACCAAAAAGAAGATTGTTACGCGAAAACGAAAATGCGTGTGCCTCCCTGAAAATTATTCAGTTGTAGAGTTTCCTACGATATGGAATGAACTGAGACAGAACGGCCAGCTGTGCGATGGCACTATCGTGTGCAGGGACATGAAATCGATTCGAGTGCATCGGGCGATACTCTCAGCCGTTAGTCCATATTTCAAAGCCATATTTATTAATTCGTTAAAAAAAGGAGAGCCAGAGGAAACGGAGATTTTTGTCGATGTCCCCAGCTATTACATGACTTTGATTCTGGATTATGCATACACAGGGACATGCACAGTAACTGCAGAAAACGTTGAATATCTATTACCGTCTGCGGATCAATTTGATGTTGTTGGTGTTATTCAGCTATGCTGTCAGTTTCTATTGCATGAACTGAGGCCGCATAACTGTCTTGGAATATTTAAATTCGCAAGATATTATTTCTGTAGTGAGctagaaaaaaaaggaaagttGTATATAAGACAGAATTTTAGCAGAATACTTAAGGAATGTAATGAATTTAAATCGCTTTCTTATGATGAATTAGAAGATATTTTGAGAGATGACGAACTGAATGTTCGAAACGAAGAAATAGTATTCCAAGCAGTTAAAACATGGGTGGAACATGATATAGAAAATAGAAGAAAATATATTCCACCGTTACTTTTGTGCGTACGGTTCGGTCACATCAGCTATAAATATTTCAAATCGAAAATATTACAATGGCAACCGGTTGCTGACGACGAGAAATGTCAAGAAGCTTTATATCCAGCCGTGGTATTTCTCACGTTGTTGGATTCGAGACCGGGTACAGAAGCAGATCTCAATGATCCGTTAGCAAGGCCTCGAATACCCTTTGAGATACTCTTTGCTGTTGGTGGCTGGAGCGCTGGCAGTCCCACTAGTTTCGTTGAAACATATGACACAAGGGCGGACCGATGGTTTCTCTCGATTCACATGGACCTAACGCCCCGCGCGTACCACGGTCTATGCACGTTGAACAACCTGATCTACATGATCGGGGGCTTCGACGGTAGTGACCATTTCAACACAGTCCGATGCTACGACCCAGTAGCAAACACTTGGCATGAACGTGCCTGTATGTATCAGGCGAGATGCTACGTCAGCGTCGTGGCTCATGagGGTCTGATCTACGCGTTGGGAGGATACAACGGTCGTACGCGCATGTCATCTGTAGAGCGCTACTACCCCGACAAGAACCAATGGGAGATGACCACTCCGATGAACAAACAACGCTCGGACGCAAGCGCAGCTTCTCTCGCCGGGAAGatatacattgtggGCGGATTCAACGGTCAGGAAGTACTGAGTTCTGCCGAGGTGTTCGATCCAGACACGAAGCAGTGGAGCTTCATCAGATCAATGCTTAGTCCTCGCTCGGGCGTCAGTCTCATTGCGTACAGAGACTGCTTGTATGCTCTCGGAGGATTCAATGGATATAGTCGGTTGAATACCGGGTCAACCACGATACCCCACGTGGAGTGCTATGATGGCGATACGATGGAGTGGTATGACGCTGCACCTATGAACCTGAACCGATCAGCGCTCAGTGCCTGTGTTTTAGCTGGCCTGCCCAACGCGCGTTCCTTCTCATACCTCGCCAAGGCCGTGCCCGCTGCCGGAGCAGATCAGGCTCACCACTCCTGA
Protein Sequence
MEFNSKHRKLSKNKNSVRTPSSSKPRLTKKKIVTRKRKCVCLPENYSVVEFPTIWNELRQNGQLCDGTIVCRDMKSIRVHRAILSAVSPYFKAIFINSLKKGEPEETEIFVDVPSYYMTLILDYAYTGTCTVTAENVEYLLPSADQFDVVGVIQLCCQFLLHELRPHNCLGIFKFARYYFCSELEKKGKLYIRQNFSRILKECNEFKSLSYDELEDILRDDELNVRNEEIVFQAVKTWVEHDIENRRKYIPPLLLCVRFGHISYKYFKSKILQWQPVADDEKCQEALYPAVVFLTLLDSRPGTEADLNDPLARPRIPFEILFAVGGWSAGSPTSFVETYDTRADRWFLSIHMDLTPRAYHGLCTLNNLIYMIGGFDGSDHFNTVRCYDPVANTWHERACMYQARCYVSVVAHEGLIYALGGYNGRTRMSSVERYYPDKNQWEMTTPMNKQRSDASAASLAGKIYIVGGFNGQEVLSSAEVFDPDTKQWSFIRSMLSPRSGVSLIAYRDCLYALGGFNGYSRLNTGSTTIPHVECYDGDTMEWYDAAPMNLNRSALSACVLAGLPNARSFSYLAKAVPAAGADQAHHS*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00035861;
90% Identity
iTF_01026466; iTF_00177313; iTF_00327201; iTF_00622977; iTF_00820225; iTF_00952833; iTF_01118465; iTF_01368257; iTF_00712066; iTF_00850914; iTF_01064802; iTF_01487842; iTF_00037955; iTF_00124419; iTF_00810243; iTF_01221731; iTF_00445348; iTF_00758404; iTF_00806852; iTF_00906308; iTF_00951972; iTF_00038981; iTF_00302277; iTF_00791333; iTF_00907173; iTF_00994469; iTF_01028453; iTF_00036966; iTF_00185446; iTF_00186406; iTF_00237895; iTF_00282567; iTF_00828071; iTF_00908999; iTF_01342343; iTF_01534087; iTF_00745928; iTF_00041033; iTF_00869801; iTF_00147658; iTF_01030378; iTF_00042795; iTF_01124715; iTF_00171980; iTF_00831372; iTF_00928844; iTF_00374349; iTF_00819309; iTF_01094189; iTF_01440269; iTF_00178350; iTF_00374350; iTF_00281519; iTF_00674415; iTF_01117487; iTF_00041936; iTF_00429168; iTF_01230768; iTF_00071633; iTF_00290833; iTF_00931601; iTF_01063889; iTF_01430065; iTF_00150770; iTF_00273746; iTF_01095090; iTF_01247250; iTF_01337010; iTF_01527474; iTF_00364179; iTF_01062963; iTF_01564819; iTF_01119508; iTF_00851957; iTF_01093269; iTF_00120662; iTF_00274550; iTF_00425590; iTF_00428278; iTF_00809302; iTF_01192854; iTF_00043703; iTF_00173207; iTF_00772151; iTF_00908055; iTF_00913751; iTF_00111800; iTF_00121592; iTF_00888408; iTF_01125592; iTF_01509720; iTF_01533208; iTF_00122553; iTF_00667673; iTF_00736729; iTF_01027481; iTF_01084409; iTF_00123514; iTF_00405146; iTF_00932794; iTF_01152314; iTF_01532250; iTF_00040027; iTF_00446363; iTF_00794811; iTF_01029404; iTF_01085532; iTF_00301341; iTF_00450301; iTF_00973917; iTF_01020445; iTF_01076669; iTF_01535069; iTF_00300382; iTF_00833214; iTF_01062014; iTF_01260254; iTF_00050079; iTF_00449311; iTF_00787807; iTF_01031263; iTF_01526207; iTF_00375456; iTF_00447392; iTF_00685600; iTF_00726592;
80% Identity
-