Basic Information

Insect: Amphimallon solstitiale
Gene Symbol: topi
Assembly: GCA_963170755.1
Location: OY720676.1:116316870-116325507[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.0015 0.48 14.1 1.3 3 21 127 145 125 146 0.93

2 13 9.8e-07 0.00032 24.1 0.9 1 23 171 193 171 193 0.97

3 13 0.015 4.9 11.0 2.0 2 23 200 221 200 221 0.95

4 13 1.3 4.3e+02 4.8 0.1 2 19 240 257 239 260 0.92

5 13 4.5e-05 0.015 18.9 0.7 2 23 326 347 325 347 0.97

6 13 0.34 1.1e+02 6.7 3.3 2 20 390 408 389 413 0.82

7 13 0.0042 1.4 12.7 0.1 1 23 543 566 543 566 0.93

8 13 0.0051 1.7 12.4 0.2 1 23 570 592 570 592 0.97

9 13 2.2e-05 0.0071 19.9 5.4 1 23 598 620 598 620 0.98

10 13 0.044 14 9.5 0.2 1 23 626 651 626 651 0.96

11 13 0.22 72 7.3 2.9 1 23 657 679 657 679 0.86

12 13 2.9e-05 0.0094 19.5 0.5 3 23 687 707 685 707 0.98

13 13 7.2e-06 0.0024 21.4 0.7 1 23 713 736 713 736 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.0015	0.48	14.1	1.3	3	21	127	145	125	146	0.93
2	13	9.8e-07	0.00032	24.1	0.9	1	23	171	193	171	193	0.97
3	13	0.015	4.9	11.0	2.0	2	23	200	221	200	221	0.95
4	13	1.3	4.3e+02	4.8	0.1	2	19	240	257	239	260	0.92
5	13	4.5e-05	0.015	18.9	0.7	2	23	326	347	325	347	0.97
6	13	0.34	1.1e+02	6.7	3.3	2	20	390	408	389	413	0.82
7	13	0.0042	1.4	12.7	0.1	1	23	543	566	543	566	0.93
8	13	0.0051	1.7	12.4	0.2	1	23	570	592	570	592	0.97
9	13	2.2e-05	0.0071	19.9	5.4	1	23	598	620	598	620	0.98
10	13	0.044	14	9.5	0.2	1	23	626	651	626	651	0.96
11	13	0.22	72	7.3	2.9	1	23	657	679	657	679	0.86
12	13	2.9e-05	0.0094	19.5	0.5	3	23	687	707	685	707	0.98
13	13	7.2e-06	0.0024	21.4	0.7	1	23	713	736	713	736	0.98

Sequence Information

Coding Sequence: ATGAATAATACAGATATAAGTTTTATAAAAGTTCATCAAATAGATCCTGATGGTTCTGTGAATTCTTACCAATATGAAGTTGATAATATGTCTCAAGAGTTTATAATGAAAACCACTCTGGCTCCTTCTTTTAGTACAAATTTAGATATACCTTTTAATTCAagtgaaaaatttaattttaagtttcGATTCTTAAATTTGGAAAATTCTTCAATCAGAGTTATAAAGATTGGAGGTGTTGAAGATCTTAATCCTATGAATTATGCGACTGAAATATCTACAGTATTAAATGATCCTTATGAAAATAAATCAGTTATTTGTGGAAATATTCTACCCAAAAGAGAATCAAAAATTCCCAATATTCCAACCATGATAATTTGTCAAAATTGTGATACAAACTTTCCTACAAAGTATCAATATCAAAGACATCAATGTGAATTTAATGCTGATAAAGTAGTTCTTAAGCCTAATGTGGACATAAAAGACATAGATAAAGGTATGAGAATGAAATTTGATTGTCCAACTTGTGGTAAGCAATTTGTTAGCAAGAATAATCTAGAACGGCATCAAACAAGTCATGATGAAACTAACATCAATGTATGTGAACAttgtaataaacaatttgtaagtgAAAATCGTTTACGTATTCATAAAGAAAATCATTGTAAAAAAGCTGGTGatatatctaaattttatagaaGTGATGTAACTGTTTGGAAATGCCTGAGTTGCTATCAAGTTTTTGCAACACCTACATCAGCTACAAAACATGCAGAGAATTGTTTTGAAAATCTTGATCCAAATGGACCAAGAAGTAGTATAGATGAAAATGAATGTAAAATTGTTTCTGATGAAATTCAGAATCTTACACATGACGCCCCAGATATAGTTGATCAAGGAATTACACTTAATGGTAAAGTCAGTGATGGTGCTACACTTAAGAATGTACAAAAATTTTTAACGGAGTTGCTTCTTCAGTGTGAATATTGCAATCGTACGTATGCTGATAAGAATTGGTTATTAAGTCACCAAAAATCACATTCCACAAGGATAAATTATGAGTGCATAACTTGTAATTTAACATTTGATTCATATGTATTAGCATCTAAACACTGGTTAACCAAATGTTCCGATGAAGCAAATCTTTTTTATTTGCCAAAACTAACATACTGTGAATATTGTGACAGAACTTTCAAATCTCATGAAATATTGTATACtcataaatttaagaaaaagcatTATACACCTAAGGTATTTGCACCAACCGCATCTAGTTCAAAGGATACGAAACAAGGAAGCTTAAAGGATAATTCCATGAAAATAGTTGAAAATAAGGAGGCAATAGTAAAATTAATAGAAGATGTACTTTTTGCTATGAATGTTCCAGCTGAAGATAaacataatgataataataatgacaAAGAAACCAGCAAGACTGCTGTTGATGATAGTACTTGTTCACAGGATATTTGTATTAAGTCAGAAATTTTTAGTGAGTCAAGCAGTTTTTCTAAATCAGATACATCACAAGATTCAGAAAAAAAGAAACGTGGTAGAAAAAGACAATCACCTAGGCACACCACTAAGACTAAACGTTTAAGTGCTATCGTTGAAAATGGTTACAAATACCAATGTGAAAGATGCGTTAAAGTTTTTGAAAGTGTAGCTGACTTAGAAAATCATAAAGAGTTAGAGCATCCTGCAAAATTTAAATGTGAGGAATGTGGTCAggtTGTTCACAGTGCAAAAGCATTGTTGATACATAGCAGAGCTCATCAAAGTTTAAAACCTTATGTTTGTGAAATTTGTAAAAGGTGTTATTCTCAAACATCACATTTATGGCAACATATGCGATTTCATCAGGGTATAAAGCCATTTGCATGTCCCCATGAAGGTTGTGAAGCCAGATATACAATTCGTCCAGATTTGAAAGATCACATTAGAAAAGTGCATACTAGAGAAAGACCATTTAAGTGTTCTGTATGTGATAAATGTTTTCTCACAGGATCGGTTTACTATCAGCACCGCTTAATACATACGAATGACCGTAGATACGGTTGTGATATTTGCCAAAAGAGATTTTTCCGTGCTGACGCCCTAAATAATCATAGAAGAATCCACACAGATGAACGTCCATATCCTTGCGATATTTGCGGCAGACAGTTTAGACAGAAAGGTGACCGCAACAAGCACGTTCGAACACAACATCCATCTCTTTGA
Protein Sequence: MNNTDISFIKVHQIDPDGSVNSYQYEVDNMSQEFIMKTTLAPSFSTNLDIPFNSSEKFNFKFRFLNLENSSIRVIKIGGVEDLNPMNYATEISTVLNDPYENKSVICGNILPKRESKIPNIPTMIICQNCDTNFPTKYQYQRHQCEFNADKVVLKPNVDIKDIDKGMRMKFDCPTCGKQFVSKNNLERHQTSHDETNINVCEHCNKQFVSENRLRIHKENHCKKAGDISKFYRSDVTVWKCLSCYQVFATPTSATKHAENCFENLDPNGPRSSIDENECKIVSDEIQNLTHDAPDIVDQGITLNGKVSDGATLKNVQKFLTELLLQCEYCNRTYADKNWLLSHQKSHSTRINYECITCNLTFDSYVLASKHWLTKCSDEANLFYLPKLTYCEYCDRTFKSHEILYTHKFKKKHYTPKVFAPTASSSKDTKQGSLKDNSMKIVENKEAIVKLIEDVLFAMNVPAEDKHNDNNNDKETSKTAVDDSTCSQDICIKSEIFSESSSFSKSDTSQDSEKKKRGRKRQSPRHTTKTKRLSAIVENGYKYQCERCVKVFESVADLENHKELEHPAKFKCEECGQVVHSAKALLIHSRAHQSLKPYVCEICKRCYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCSVCDKCFLTGSVYYQHRLIHTNDRRYGCDICQKRFFRADALNNHRRIHTDERPYPCDICGRQFRQKGDRNKHVRTQHPSL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00627609;
90% Identity: iTF_00990900;
80% Identity: -