Basic Information

Insect: Amorpha juglandis
Gene Symbol: BAZ2B
Assembly: GCA_949126905.1
Location: OX421373.1:4022545-4070775[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 1.1e-11 3.8e-08 33.2 0.0 4 74 658 731 655 734 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	1.1e-11	3.8e-08	33.2	0.0	4	74	658	731	655	734	0.87

Sequence Information

Coding Sequence: ATGTTAAAGTCGTCGCGGCATTTGGATTATGGTTATATGATTGAAAGGCGTGGTATGGACAAGGAGGGCGGCGAGGGCGCCGAGGCGGCGGGAAAGGCGCCTCCCGATGGACTGCTCGACGCGGCCGGCCTCTTCGGAGCATACTGGGGTCGAGATGGCaccggcggcggtgcggcggcgCAGGCCCAGGTGCAGGCGCAGGCCGCACTGTTCGGCTTCGGCTCGCGCTACCCGCCGCCTACCACGCTCGGCGTCGCCGCCAACCAGGCAGCCTCGCTTGGACTACATCCTGCCGCTAGCGCAGCGTGGTGGTCCATGGCGTCTCATCTAGCGGCGCAGGACTACTTGGCGCGACTGCAGGCGTCAGGGCTGAACTTCCCGCCGATGGCTGATCCGTACGCTGCGCTCTCGGCGCTTTCAGGAGGCTCGCTCAAACAGAACAAGCCTGTCAAACCGCCTGGAAGGAATGAAAGGTCTGGTCGCGGCAGCACGTCGTCAAGCGCAACCAACAAGGAGAAGAGTCCATccaccagcaccgcctcgccgAGCATGAGTGAGTGGGGATCATCGTACGGGTTCCCGAAAACCTCGTCCCCTTCAACGATGCACTCGCAACAATCGTTGTCTAGTCTCGCGTCACTCAACAGCCTCGTGTCTGCGCCGCACCAAGCCAAAAGCACGCCGAAGCAACAGACGCCTCCTTCTTCGCAGAGCAGAAAGTCATCATCGAGCAGTTCATGTGGCAAGGGCAAGGAGCGCGAGCTGGCGTTGTTGCGCGGAGACCTGATGCTGGCGCAGGCCGCCGCGCACGGAGCGTACCACGCCGCCGTCGCAGCCGCCGCCAAGGGGAAGAATATGTCCCCGCTATACCCGTTTGGCATGCCAGGTTCCGAGAAGGATCGGCATGTGAGCATTGATTCGCTCACTGGTCTGCCACACACTATACTcagTGCGGCTTTGGAAGGAGGTGATCCGTCATCGGTACTAGGCGGTGTGAGACTGCCGCCGGATACTGAAATCATCAAATACACCTCATCATTAGCGGGGCCAAAGGCCCCGCCCGGTTCAACAAACAGGGGTCGCAAGAAGACGATATCGTTGGACCCGCCGCAGGTGTCCGTGCATCCGTCCTCAGCGGACAGAAGCACGCCGCTGCCCAGCAAGAGGGCTAAAGTGGACGAATATGGCAACTCCCGTTCGTCAGTGGAGGTGATCCGGCTTCCTAATAAACCGGACAGGCCCGGACATAACTCCGTGTCCGGAACACCGCCGCCGAACCTGTCCGATTATGCTGGTATATCGAGGGAGTTACTACAAACAATAGCTAGTCAGAGCGGCGTCAGTCTTGCCGCGTTAGAGAGACAGCTCGCCGGGTCCACTGCCTCTGCAGATTCCGGCATCAACATGAGCAGCAAGTCAATGACGGCTAGCGGTGAGGACAGCCCGCTGGATCTCGGGCTCAAGGCCGCCGTCGACGAGGACGCGCCGCTCAACCTCTCGCTCAAACCTACGCCACCGAGCAACCAAGCATCTGACGCGTTGTCGCGGCTCACGTCACTCAGCAGTTCACTCAGCGCGTCATCACAAAACGAAAGGATATCTCGTCGCAAACCAGGTGCAAAGCCGCGTCGCGTGGTGCCCGAGCTGAACTCGCACGTCGCAGACTCGCCGCGGCCCAAGTCTAGTGGCAGCGAGGATAGTGAATCAATAGCTGGTTGGCCGGCGCGCGAGTCTCGGCCGCGGAACCTGGGCCGCGGCGTCAGCAAACCGAAGAAGAACACCGTCGCCTCGCTACTGGCGCAGTCCCGCGCACTCGGGCTGCGGCCCTCGCTGCCGCACCACCTGCTGCCAGACACTGATATCGAGAAGCTGAAGGCGCTGCTGGGCGAGGCGGCGAGCACGGACTCGGAGTGTCCGTCGGACAGCTGCCCGTCGGACTCGGACGCGAGCGACACGGGCCGCCGCTCGCACGACTCGCAGCTCAGGCTGCCGCTGGCACTCGGCTGGAAGCGTGTGACTGTGATCAAGGGTCTGTCCCGTAACTGTAGCATCAAAGGTGATGTGACGTACGCACCGCCAGAACCACACTCCAACATCAAAGTCAAGTCCATGCAGGAACTGCAAGCGTTTCTGGATGCGAACCCGTGCCCGCCGCTGTGTCCTGACAACTTCAGTTTCAGCGCACGCACTATACTAGGCGAATATGTACAGCCGTGCGCAGAAGTTGCGGATCCACTCGTTTTTAATGAAACCGAGATTACAAAAAGGTTGGAAGAAGCGCGTGCACTAGTAAGCGCGTGCGGCAGCcgtcccgcgccgccgcccgtgGACCGGCGCATCGAGCTGGCGCGGCTGCAGCAGGCCGCGCGGGACGCGCGCCGCGACCACCACCATCGCTCCAGGGACCAGGCTCGTCTAGTCAGAGAGCTAGAAAAATCTGAAAAAGCTGAAATGGTAAAAAGAGAAAAAGAAGCCAGGAGTCAGCAGCTATTAGAGCATATCAACAAGAACAGAACACAACTGACCATAGAGCCACTGCCTACCGTACCGAAAAGCGAGGAATGGAAAATACCGGATATAGTGATGGGACCGGCGACGAAAACCCAAAGGGATAGAACGATGCCTCCTATAAGCCTGTCGCTCATACCAGTCAGTGGTCCAAAAGACCAATCACCTATACGGAACCTCCTCGAACAGCCTTGGAAGGGTGACGTCGAAGAGTACAATGCATTAGATAAAATGAAAGACTTTGCTGAGAAAGCGGCGTTTGACCTACCAAAACGTAAAGACAAGTACGACTTTACATTAATGAAGGCGGCTGAAAAGAAAAAGGCGCCAGACAAAGAGAACAATCTAGAAAAATTGATCGAATCTTACTCGAGAATCACAGAGTTCATCAACGGTTGTGATTGGTCCAAACTGCCCGCTGATAAAAAGACTGAGGACCCTAAAGCATTGGAACAGAAATATTTGAACGCTAAAAACGAGTTCATGTCTCAAAATTTAAGTCTAATGCCTAAAGACAATCCTAAGTCAGTGCTCAAAGAAGTTATCGACTTAAGCGAGGATGACGACAACATTTTGACTGATATAATAACGAAAAAGATAAGCAAAGGAACTTTCAGTGTTGGAAAAGACGGCGCTTTATCGATATCGGTACATCCTTACGGCAAGGAGTACGGATTGGCTAAAAAGAGAAAGCAAGAGGAAATGGAGAAACAGAAGATTGAAGATCAGGCTAAAAAGCAACAGGAAAGGGAAATAAAACGGCAACAAGCCCTCCTATTAAAAGAGCAGCAAAAGTATATAACCGAGGAGCGTGAAAGAAGACGACAGCATACAACTTTCATCAGACAGTTAGACTCAAGAAGAAGATGGGAAGAGAGAGAGAGGAAAAAGCACCAGAACCTGCTGGACCGGCTGCTGGTGAAAGAGAAGAAGCTACAACAGCGGCGGAAAGAAATGGAACTCCTATCTGAGTTAAGGCGGCCGCAAGAAGACTCGACTCTGTCTGACCAGAAACCAATGCCTACACTAAACAGGATCCCCGGCCTGAAACTGCCTGGACAGGCAATGGCCGACATACTGCAAGTGTACGAATTTATACACAACTTTGGACAAACACTTGGATTTGACATGGATGCCATACCAACGTTGAACACGTTCCAACTGGCATTACTTCCGGACTGCAGCACTGACGCTGAAGAGGAGCTCGTACAAGTTCTCACACAATTACTCATCACAGCTATCGAGGACCCGGGTATCCCCCACCCGGGTCGGCACACGACGCTACTCGGACATGCGATCCGCATGGGAGACATCACTCCGCACAACCTGAGCGAAGTGTTGCGCATCTACCTATACGCTAATGCTACGGGCGAAGTGAAGGCGCTTACTGGTCTGACTGCGGAACGTGAGAGGGAACGTCGAGTGGCCGACCACCATCAGAACGACGCGGAGATGTTACAGACAGGCGCCAGCACCAAGAACGCCGCCTACTACGAGCATCTGCATAATAACAACACTTACAAACTCGCAGaGGCTCTCCGCGACAAGCCGTTCCTAGCATTAAACGCGACGACAAAAGCGCGAGTGCTAGCGTTCCTGTGCGACGAACTGCTGCAGAACAAGGCGGTGCTGCGGCAAATAGACGGCGCGCTCGAACACCTTAACCAACTGCGCAAGGAGCGGTATCTCATGGACATGAAAATCCGGAAGGTGCGCGTACTACATCAGCGCAAGTTACGGTCGGAGCAGGCAGAGAAGCAACAAGCACTCGCCCTGGAACGTATGCAGCGGCTCGTGGACGAGAGCGCCGCGAGTGTGCACGCCGCCTCGCCGCTGCCTCCGCCGCCGCCGCTCAGCGATCAAGAGAATCCACCAAGTTCAGAAAAAGAGGACTCGccgaaaaaaattgaaaaagaaGAGTCTCCACATCCAGAAGATAAAATAGCTCCCGATTTATCGTCGCCATATAAGGATAACGTGCCGGACGAGAGCGACAAGGAACTATCACCGTTAAAGGATCTGTCCAATAGTATAAAAGGAAAGGAAATTATGAACAACAATAAGGACGAATGTTCCCCGGCAGATAACTCCAAGATCGATAAAGATAGTGTCATGGGAGATGATGTTTTAAGTGATTTGGAAAGTGAAGGAACGCAACCAGAAGAGgaTGAAGACAAAAACTTATCAGCAGAAGAGCTTTCTAGGAAATTAGAGAAATTATTACGACAATCAGAACAACAGCTGCAACAATTGCAAGCTGGATCTCATGCGCTAAGAGCTACGTGTTACGGACAGGATCGGTACTGGCGTCGTTACTGGTCTCTCGGCAAGTGCGGAGGTATCTTCGTGGAAGGCATGGAGTCAGCTCAGCCGGAGATCATGCAGTATCAGCAGACGCTTGAGAGTAATGCACTTCAGGACAAACAGGATACTTGCAAGAGGAAAAAGAAGAGCGTGAAAGAGAAGAAAGAGCAGATACCAGCACCAGAGCCAGATAAAACCGAGGAGAcggaagcgcagcagcaagagGAAGCTCTGAAGACACAACTTGAGCTGATGAGCATAAAGTCCGAACTCAACCTAAGCGATCACACGCAAATCATCAAGTACGAGCCCAATGTTAAGCACGGCGCTTGTAAGGTTGAAGGATCATCAATAAAAATGGAAGAGAAATATAtccaacaaaaacaaaacaacgaaGAACAAGACATGCTTGACATCGAAGATTCTATCCCGACCGCGTTCTTAGTACAAAAACCTTCGCATAAACCGATATACGCGCAACCCACGGAACCAACCGACAAACCGCAAGAAGCCAAAGTTGAGCCAAAAACGGAAATCATCGAGAAAGAAGAACCAGAAGATAGCAAAGACCAACTCGTTAACAACCTCGAAGAACTGCGTAAAATGGCGGAAGCAGTATCGTCACAACTCGCCGCGGCGAAACAAGCAGAAGAAAAACAAGAGAGAGAGTATAAAGAGGAAGAAGAATTCATGGAGCAAGATGCAGCACATGGTTACTTATATACAAAGATGCTTGAAGGCAAATGGTTCTCAATACTACGTCACGAGAGTTCGTTTCTATCGAACATTAACGAACAGGACAAGGCTGACGTGCCTATGTATTGTGATAACGAACATACTTGCGCAGAAGTTGCTCTTTCTCAAGGTCACAAGTGGGATGTTTCGAACAATTTACATTTACTGAATGATCCGAGCCTGTTTACATTAAATAGTATGGTGACTAGTGTCCAAGTGCCAACGAATAGTGTGTATGCAGATAGCAGTTTAACTATGTCAGGGTTAGATCAAGATATGATGAACGCAAGTTTGAATAAGGAGCCGGTGCCCGAAGTCGAGCTAGAGGAGGAGAATAAAGATCAGGACAACGATCTCGAAAAGGAACTGCAAGCTGACGCGATCAAGAACGATCTCGCAATCCAGAAAGCTAAAGCTAACAGTTTAACAAGTCTAGGCCTATTGAACTTCAATGCTCTGTCGACGTATGTGACGTGTGATAGTCCGCCGCCCATACACATGTCGCCTGAGGAACTGGAACAACTCGAGTACTGCAAGCTGCACGGACTGCCCAAGAAGATCGAAGGCACCTTCGTACCAAAGGAGTTAAGATACGGCTGGTGGCGAATCACAGAACCGGATCAGCTGAAAGACCTAATGGAGTCGTTACATCCAAGAGGAGTAAGAGAAAGGGAACTGCACGCAGCCTTCGCCAACCACCTGCCTACTGTTAATAACAAAGTGTACATAGAGAAAGGCGACTTCCACAGTACGGAGTTGTCGGTATCGCACGTTGACCGGGTGATCGCGATGAACGGCGGGTACCCGAGTCCTGACGCGGCTGGCTCCTTCTCTGTCGCCACAGCCAGGCGGGTCGACATGCAGATCTTGTCTATGGTGGAGCAACTAGAAGAGCGTGTAGCGGCGGCCTCGATGCAGGTGAAGGGCTGGCGACCGTCGCGTGTGTCGCTCCCGGACGGGGGGGCGGGGGGCGTGACGGGGGGCGCGGGGGGCCTGGCGGGGGGCGCCGAGATAGTCTCCCGCGCGAGGCACAAGCTCGCCGCGGTCGAGGCACACATCGAGCGTCGATACCTCAAACCACCTTTGGTACAAAGGTATGCTAGCACGACAGAAGCGAATATAGGAGCAGTGTTGCAAGGTGAACATGGCAACGCGTCTGCACCTTCACCGCAGAACTCTGATAATGCTAGTGAAGGAAAAGCGGATAACAAAGGCATAGCTCGCGGTCTTGCCACGTGGCGGGAAGCGGTGGCGAGATGCAATACATCAGCACAGTTGGCGATGCTGCTGCAGGCCTTAGAAGCCGGCGTGGCTTGGGACAAAAGCATTATGAAAGCAAACTGCCAGTTCTGCTTGAGTGGTGACAACGAAGACCAGCTGTTACTGTGCGACGGCTGCGACAAGGGCTACCACACGTACTGCTTCAAGCCGCGGATGGACAAAATACCTGAAGGAGACTGGTAA
Protein Sequence: MLKSSRHLDYGYMIERRGMDKEGGEGAEAAGKAPPDGLLDAAGLFGAYWGRDGTGGGAAAQAQVQAQAALFGFGSRYPPPTTLGVAANQAASLGLHPAASAAWWSMASHLAAQDYLARLQASGLNFPPMADPYAALSALSGGSLKQNKPVKPPGRNERSGRGSTSSSATNKEKSPSTSTASPSMSEWGSSYGFPKTSSPSTMHSQQSLSSLASLNSLVSAPHQAKSTPKQQTPPSSQSRKSSSSSSCGKGKERELALLRGDLMLAQAAAHGAYHAAVAAAAKGKNMSPLYPFGMPGSEKDRHVSIDSLTGLPHTILSAALEGGDPSSVLGGVRLPPDTEIIKYTSSLAGPKAPPGSTNRGRKKTISLDPPQVSVHPSSADRSTPLPSKRAKVDEYGNSRSSVEVIRLPNKPDRPGHNSVSGTPPPNLSDYAGISRELLQTIASQSGVSLAALERQLAGSTASADSGINMSSKSMTASGEDSPLDLGLKAAVDEDAPLNLSLKPTPPSNQASDALSRLTSLSSSLSASSQNERISRRKPGAKPRRVVPELNSHVADSPRPKSSGSEDSESIAGWPARESRPRNLGRGVSKPKKNTVASLLAQSRALGLRPSLPHHLLPDTDIEKLKALLGEAASTDSECPSDSCPSDSDASDTGRRSHDSQLRLPLALGWKRVTVIKGLSRNCSIKGDVTYAPPEPHSNIKVKSMQELQAFLDANPCPPLCPDNFSFSARTILGEYVQPCAEVADPLVFNETEITKRLEEARALVSACGSRPAPPPVDRRIELARLQQAARDARRDHHHRSRDQARLVRELEKSEKAEMVKREKEARSQQLLEHINKNRTQLTIEPLPTVPKSEEWKIPDIVMGPATKTQRDRTMPPISLSLIPVSGPKDQSPIRNLLEQPWKGDVEEYNALDKMKDFAEKAAFDLPKRKDKYDFTLMKAAEKKKAPDKENNLEKLIESYSRITEFINGCDWSKLPADKKTEDPKALEQKYLNAKNEFMSQNLSLMPKDNPKSVLKEVIDLSEDDDNILTDIITKKISKGTFSVGKDGALSISVHPYGKEYGLAKKRKQEEMEKQKIEDQAKKQQEREIKRQQALLLKEQQKYITEERERRRQHTTFIRQLDSRRRWEERERKKHQNLLDRLLVKEKKLQQRRKEMELLSELRRPQEDSTLSDQKPMPTLNRIPGLKLPGQAMADILQVYEFIHNFGQTLGFDMDAIPTLNTFQLALLPDCSTDAEEELVQVLTQLLITAIEDPGIPHPGRHTTLLGHAIRMGDITPHNLSEVLRIYLYANATGEVKALTGLTAERERERRVADHHQNDAEMLQTGASTKNAAYYEHLHNNNTYKLAEALRDKPFLALNATTKARVLAFLCDELLQNKAVLRQIDGALEHLNQLRKERYLMDMKIRKVRVLHQRKLRSEQAEKQQALALERMQRLVDESAASVHAASPLPPPPPLSDQENPPSSEKEDSPKKIEKEESPHPEDKIAPDLSSPYKDNVPDESDKELSPLKDLSNSIKGKEIMNNNKDECSPADNSKIDKDSVMGDDVLSDLESEGTQPEEDEDKNLSAEELSRKLEKLLRQSEQQLQQLQAGSHALRATCYGQDRYWRRYWSLGKCGGIFVEGMESAQPEIMQYQQTLESNALQDKQDTCKRKKKSVKEKKEQIPAPEPDKTEETEAQQQEEALKTQLELMSIKSELNLSDHTQIIKYEPNVKHGACKVEGSSIKMEEKYIQQKQNNEEQDMLDIEDSIPTAFLVQKPSHKPIYAQPTEPTDKPQEAKVEPKTEIIEKEEPEDSKDQLVNNLEELRKMAEAVSSQLAAAKQAEEKQEREYKEEEEFMEQDAAHGYLYTKMLEGKWFSILRHESSFLSNINEQDKADVPMYCDNEHTCAEVALSQGHKWDVSNNLHLLNDPSLFTLNSMVTSVQVPTNSVYADSSLTMSGLDQDMMNASLNKEPVPEVELEEENKDQDNDLEKELQADAIKNDLAIQKAKANSLTSLGLLNFNALSTYVTCDSPPPIHMSPEELEQLEYCKLHGLPKKIEGTFVPKELRYGWWRITEPDQLKDLMESLHPRGVRERELHAAFANHLPTVNNKVYIEKGDFHSTELSVSHVDRVIAMNGGYPSPDAAGSFSVATARRVDMQILSMVEQLEERVAAASMQVKGWRPSRVSLPDGGAGGVTGGAGGLAGGAEIVSRARHKLAAVEAHIERRYLKPPLVQRYASTTEANIGAVLQGEHGNASAPSPQNSDNASEGKADNKGIARGLATWREAVARCNTSAQLAMLLQALEAGVAWDKSIMKANCQFCLSGDNEDQLLLCDGCDKGYHTYCFKPRMDKIPEGDW

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01010381;
90% Identity: iTF_00858570;
80% Identity: -