Acom004724.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Amiota communis
Gene Symbol
su(Hw)
Assembly
GCA_037043315.1
Location
JBAMAV010000371.1:1636924-1639702[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0041 0.49 11.8 1.4 1 20 135 154 135 156 0.94
2 12 2e-05 0.0024 19.1 0.3 3 23 207 228 205 228 0.93
3 12 0.012 1.4 10.4 0.2 1 23 234 256 234 256 0.95
4 12 6.8e-07 8e-05 23.7 2.5 1 21 263 283 263 284 0.95
5 12 1.9e-06 0.00023 22.3 1.0 2 23 296 317 295 317 0.96
6 12 9.4e-05 0.011 17.0 5.3 1 23 328 350 328 350 0.99
7 12 0.00098 0.12 13.8 0.6 3 23 358 378 356 378 0.97
8 12 1.5e-06 0.00018 22.6 0.5 1 23 384 406 384 406 0.99
9 12 4.5e-06 0.00053 21.1 3.2 1 23 412 434 412 434 0.98
10 12 0.012 1.5 10.3 1.4 1 23 438 460 438 460 0.97
11 12 0.0011 0.13 13.6 2.6 1 20 472 491 472 493 0.94
12 12 0.0002 0.023 15.9 0.1 3 23 514 535 513 535 0.95

Sequence Information

Coding Sequence
ATGAGTAAAGCAGCAGTTGAACCAACTACCACTGGCGGCAACGAAAGACCGAAGCGTAATAGTGCTTCGGGcattaaaatcttaaatgaTGAAAAGATTTCGCCCTTACCAGCTAAAGGATCTTCGCTATCCATTGCAAAACCCAGATTAGCCGCTTCCAAGAAGAGTCAAGAGCATTATGTGCTACAAAGTGTTAAAAGTGAATCAAATAAAACGACTGGTGGAGGATCTGTTAGTACTTTAGACGAAGACGATACCATCATTGTTCTTGccgaaaacaaaaacgaagagAATGCAATCGTATCGGAGCATGGTCAACGAAGCGGCGAGATCACTGAAGAATATAACATCAGTGGTGAGGAGGGCGATGGTGAAAACGATCGTGTTAAAGAAATCGTGGAGCATGTCTGTGGCAGATGCTACAAAACATTCCGTCGCGTCAAAAGTCTCCTGAAGCATTTAGAGTTTTGTCGCTATGACAGTGGCTATCATTTGCGTAAGGCAGACATGTTAAAGAACTTGGAAAAGATCGAAAAGGATGCTGCCGTTATGGAGAAGAAAGATATATGCTTCTGTTGCAGTGAAAGCTATGATACATTTCATCTTGGACATATTAATTGTCCCGATTGTCCGAAATCATTTAAGTCGCAACTAAGCTATGAGcgtcatatttttataacacatTCGGAATTCACTGATTACCCTTGTTCCATATGCAATGCCAAGTTACGTAGTAGCACATTGCTAAAACTACATGAAGAGCAGCACAAAACTCGTGGAAAGCCATTTGCATGTAAAATTTGTGGCAAGGATTTCACTCGCTCTTACCATCTTAAACGCCACCAAAAGTATTCATCATGCTCAACCAATGAAAATGATACATTAAGCTGCAAGGTATGCGATAAGGTTTTCTATCGTTTGGATAATTTGCGTTCCCATTTGAAGCAACATATTGGAACGCAAGTTGCAAAGAAGCCAGAATACATGTGTCATGTATGTAAAAACTGCTTTTACAGTTTGTCGACTTTAAACATACATATTCGAACACATACTGGTGAAAAACCATTTGGCTGTGATCTGTGCGAAAAGAAGTTTTCAGCCCTAGTGGCACTAAAGAAACATCGTCGCTATCATACTGGAGAGAAACCATACACTTGCACTGTGTGTGGTCAATCATTTGCAGTCAAAGAAGTGCTCAATCGTCATATGAAACGGCATACCGGCGAACGTCCACATAAATGTAATGTATGTGACAAGAGTTTCATACAAGCAACACAGTTGCGTACTCATTCAAAAACTCATCTAAGACCATTTAGCTGTTTATTATGCGAAGATAAGTTCAAAACACAGAAACAATTAGATCGCCACGTCAAGGAGCACTTATCTACAAAACGCAAGAAATCTGCTGCTAAATTCGCTTGCAATAAATGTAAACTTTCTTTCAGTTTTCAACATCAATTAAGAACACATTACGAGAACGGTTGTAACAAAGgaCCCATTAAACGCATGAAACGTAACAGGGTCAGCGATCGCAGAGATTGTGCAATTTGCGATAAGATTTTCGATACGACAGATGATCTACGTAGTCATATTCTTAATGTTCATGAATGTGATCCAGAAGATATATTTGGTGAAataccaccatcaccaccaccagcaccagtACCAGCTAAGAAACGCAGGAAACTAACTAAAAAAGAATCACCAGTTGATGCTTCTGCTGCTTCTGGAAGTCAAttgatttcaacaaataaGGAAAATGGTGTAGTTGTCCGCGAGTTTCTTGTCGACGAAGTTCAAGCTGTTGGCTCAAGTTCACATCAAACTATTGTACTGGAGAATGAAACATACACTATTTTCCCAATTGATGACGATTCAGAAAACAATGATTCCAAACCGAGTGTTTCAAGTGAAACTAAACCCATAGTTTCACCGGCTGTAAAGAAAGAACAACGCAAATCTTTGGCAGCCAGTTTAGCTGCTGCTATTGCGGACAATGAAGAAGATGTGGAGTTAAGTGAAGATGAAAACTCTGATGAAATGACAGAAGAAGACTTAAAACTTAAAGATAATGTAGCCAAATTATTGGATATGTTAGTGGATAATTCTACACTAAAAAAATTTGGTTGGCCTGAAACATCAGAAGAAATCGTATTATGTCAAGTTATTGAAAATTGCGGACACGAGTTaactgatgataatgaaaattatcgTCAACTTGACTATGGAACGCGCATGCGtgaatatttgaaattgttattcAAACTGGTGATACATAACGATTCCATTAAGGAATTGCTAAACAATTATCCAATTGATGAAGTCATAGAATATGTTCtgggtaatgatgatgaggatgacgatgaagatgaaTCGTATGGAAATGGTGAAGGTGAAGGCGAAGGTGGTGAGGAGATTgaagataacaaaaaagaaatagtaaCTTAA
Protein Sequence
MSKAAVEPTTTGGNERPKRNSASGIKILNDEKISPLPAKGSSLSIAKPRLAASKKSQEHYVLQSVKSESNKTTGGGSVSTLDEDDTIIVLAENKNEENAIVSEHGQRSGEITEEYNISGEEGDGENDRVKEIVEHVCGRCYKTFRRVKSLLKHLEFCRYDSGYHLRKADMLKNLEKIEKDAAVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKSQLSYERHIFITHSEFTDYPCSICNAKLRSSTLLKLHEEQHKTRGKPFACKICGKDFTRSYHLKRHQKYSSCSTNENDTLSCKVCDKVFYRLDNLRSHLKQHIGTQVAKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFGCDLCEKKFSALVALKKHRRYHTGEKPYTCTVCGQSFAVKEVLNRHMKRHTGERPHKCNVCDKSFIQATQLRTHSKTHLRPFSCLLCEDKFKTQKQLDRHVKEHLSTKRKKSAAKFACNKCKLSFSFQHQLRTHYENGCNKGPIKRMKRNRVSDRRDCAICDKIFDTTDDLRSHILNVHECDPEDIFGEIPPSPPPAPVPAKKRRKLTKKESPVDASAASGSQLISTNKENGVVVREFLVDEVQAVGSSSHQTIVLENETYTIFPIDDDSENNDSKPSVSSETKPIVSPAVKKEQRKSLAASLAAAIADNEEDVELSEDENSDEMTEEDLKLKDNVAKLLDMLVDNSTLKKFGWPETSEEIVLCQVIENCGHELTDDNENYRQLDYGTRMREYLKLLFKLVIHNDSIKELLNNYPIDEVIEYVLGNDDEDDDEDESYGNGEGEGEGGEEIEDNKKEIVT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00062987;
90% Identity
-
80% Identity
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