Basic Information

Gene Symbol
Bgb
Assembly
GCA_933228735.2
Location
OW121686.1:15859427-15868115[-]

Transcription Factor Domain

TF Family
CBF
Domain
CBF_beta domain
PFAM
PF02312
TF Group
Beta-Scaffold Factors
Description
Core binding factor (CBF) is a heterodimeric transcription factor essential for genetic regulation of hematopoiesis and osteogenesis. The beta subunit enhances DNA-binding ability of the alpha subunit in vitro, and has been show to have a structure related to the OB fold [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 3.6e-73 6.3e-69 230.9 0.0 1 162 32 190 32 194 0.97

Sequence Information

Coding Sequence
ATGATGCACACCATGAGCGATCATCCGGTCCTGCCGTTCGACGGAATGGGCCTCTATCCTCAACCGCGTCCACGCTTCGTCAATGTCATCAAAATGCCGAAGGTCGTGCCCGATCAGAAGGCCAAGTTCGAGAACGACGAACTCTTCAGGAGGCTCAGTCGCGAGTGCGAGATACGATTCACCGGCCATCGAGATCGACCTCTGGAGGAGCGTCAACGACGATTTCAAGATGGCTGCCGCGAGGGCCACACCGAAGTCGCGTTCGCGGCTTTGGGCACGAATCTTCAGCCGACCTTCGGTCCGACAGCGGGAAACTACGATAGCGAGCCGGGCCATTGCGACTTCGAGAAGGAACGCGGCAAGGTCCACTTTCGATCGCCGCTGATAATGAACGGCGTGTGCGTCATGCTGCGCGGTTGGTTGGATCTTCAGCGGCTGGACGGCGTCGCTTGCCTCGAGTTCGACGAGGAGGCCGCGGCTCGCGAGGACGCCGAGTTGCGGGTCCAGCTCGAGTGCTACAACAACAGATTGCGGCTCTTCGACGAGAAACAACGAGCCTACCGCAGCGGAGCGGCGCAGCCTCCGCATCTCAAccatcaccatcatcatcatctcAACGTCCACCACGGTCATCACGTGACCAGCGCCGGTGCCGGCGGCGGGGAGCCCCACAACGAGATGGAGGTCGGTCTCCGAGCCTACTGA
Protein Sequence
MMHTMSDHPVLPFDGMGLYPQPRPRFVNVIKMPKVVPDQKAKFENDELFRRLSRECEIRFTGHRDRPLEERQRRFQDGCREGHTEVAFAALGTNLQPTFGPTAGNYDSEPGHCDFEKERGKVHFRSPLIMNGVCVMLRGWLDLQRLDGVACLEFDEEAAAREDAELRVQLECYNNRLRLFDEKQRAYRSGAAQPPHLNHHHHHHLNVHHGHHVTSAGAGGGEPHNEMEVGLRAY