Apro010118.1
Basic Information
- Insect
- Amblyjoppa proteus
- Gene Symbol
- -
- Assembly
- GCA_963922035.1
- Location
- OY998230.1:41262295-41265077[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.62 60 4.8 0.1 2 19 121 137 120 140 0.87 2 14 0.00026 0.025 15.5 0.2 2 20 147 165 146 166 0.95 3 14 0.0051 0.49 11.4 3.1 1 23 174 197 174 197 0.93 4 14 3.6e-06 0.00035 21.3 0.9 1 23 203 225 203 225 0.98 5 14 2.9e-05 0.0027 18.5 1.4 1 23 373 395 373 395 0.97 6 14 0.014 1.3 10.1 0.2 2 22 405 425 404 425 0.93 7 14 0.0003 0.029 15.3 2.7 1 20 447 466 447 469 0.92 8 14 0.0012 0.11 13.4 0.7 1 23 474 497 474 497 0.95 9 14 1.7e-06 0.00016 22.4 0.3 1 23 503 525 503 525 0.98 10 14 0.0023 0.22 12.5 6.3 1 23 532 554 532 554 0.98 11 14 8.5e-05 0.0081 17.0 0.4 3 23 562 582 560 582 0.97 12 14 0.00046 0.044 14.7 0.2 1 23 588 611 588 611 0.96 13 14 0.096 9.2 7.4 0.1 1 23 625 647 625 647 0.96 14 14 0.12 12 7.1 0.0 2 23 870 891 869 891 0.96
Sequence Information
- Coding Sequence
- ATGGAAACGCAAGACAACGATCAGGCCTATGTTACGTTTCCCATTGGCGGAGTCCACGCAGCTATCCAGCAAAATATAATATCCCACGAGAAGATACGCGAGCCGAACGAATATACGCGGACAAAGGTAGCGGCAAACGGCTTGTCCGCCAATATATCAATGGAGCAGTCGGACGAAGAAGGAGAGAAGTCTGAGGTTTATCCGATTTACGTAAAACAGGAGGAGCATCAGAGATGTCGacggcggcagcagcagccacagcatcagcatcagtaTACATCGGGAGACGATGAATCAATGGCTGTGGAAGCCCTTAGACAGCTCGGCGGTATGTATCCGTGTTAcgaggacaaaaaaatgagCTGTCCGAACtgcacaaaaatatttatggaaACCGATCTGGCAAAGCACAATGAAACATGCGAGAGCATTAAATTATCATGTACAACTTGCGGCGAGAAATTTGAGAGAAAACAGGATTTGAACAATCATATTGTTTGTCATCAAGTGGATAGACCGCACGCGTGTCGTACTTGCGGCAATCTTTTTCATTCCAAAGCTAATCTGCAGAGACACATGTCACAGGTACATCAGACAGAAAAACCTCATAAATGTACGATATGTGGTGCTGATTTTCAGCGTCCATCGAGCTTATCAAATCACATGAAGATTCATACGTATGTCGCTGGCAGAGCGATAATGCAGTCGCAAATAAATTCCAACTCTCAATCGGCCGAAACATTTGGAAAGTGGCAGGAGAGCGAGCTGCAAAATAGTTCCATAACTTCGTCACCCGTTCaatccaactcgaattatgacgTATCGCAGGTTCAATGGTCGGTACcttcttacaatttttcaaatgatcAAACAACCACCATAGCTATTGGTCAAGAGAAAATTGGTTCTCCACAAGAGTTCACAGTTATGCCGAATGGTGAAGTAACTCAGTTTGAATATGCGCAACAGACTTCTATGACAAATCAGTACAGTTTATCGATTAATTCCTTTGGCAATTCGATGGACTCTATGGTTAAAGTTGAATCTATTCCGTTCACCTCGGAATCTCGAAGAAACTACGTCGAGATAGAGATTAACGAATCGCCCTCAAAGTGTCACACGTGCACTCATTGCGGGGTTAGCTTCTCCCAAGCTACCGCACTTGCTTCCCATGAGAAGATTCACGTAGCTAAAAATTGGACAATGCCGATCGAATGCGAGTTCTGCGACAAACAGTTTCAGGACGGCAATCATCTAGCCACCCATCAGATTACCTGCGCAAAGAAACTTATGCAGAATAACATCGAGCAAGGCGTTCCGAGCGTCAAATGGGGAAAGCATGCGTGTACGGAGTGCGGCAAGAAGTTTACTACTAAACAAAAGATGTTCAGGCATCAGTGGATCCACCGTAAGAAAACGCATTCCTGTGAAATTTGCGGGACCCaattcgaaaaacaaaatcaactGGACGAGCATCGTTTGTCAGCTCATCCGGGAGACTCGCCGTTCACATGTAGCGAGTGCGGAAAGAGTTTCGTTTCTCGTCAAGGTCTCTGGGAGCACGGAAGAACTCACGCCGGAAGTCCAGCGCATTTCCACTGCGACACGTGTTCGAAGACATTCTCATCGCGGCAGGGCTATCTCATTCATCATCGTACCCACACCGGTGAAAGACCGTATGGCTGTAAATATTGTTGGAAAGCGTTCAGAGATGGTGGAACGTTGAGAAAGCATGAGCGCATTCACACGGGTGAAAGACCCCACGTTTGTCCTCTGTGCTCTCGAGCGTTCAATCAAAAAGTCGTATTGCGCGAGCACGTTCGATGGGTTCACGCGGCCGGTAAGAACGACACGGATTTCACTGGTCCTCCGTATCCGTGTCCGCTGTGCGGTGCATTTAATCAAGATCGTGACGAGCTATGCGCTCACATAGTCAAGCACTCGGATCAGATGATAGCCGAGGCGAAAGCCAAGACCAACAATAACGCGCCAAAGACAAAACCGAgtaagaaaaaatcaaaaactaaTTGTAATTCGAGACGGAAAAATATCGGCGATGGAATGGTATCCCGGAACGAGCAAAATGAGGCTCTCCTATCGATAGCCGAGACCGCGGAAGAAGCTGACAAAAATAATGACGGTAATAAAACGGAAGTTCATGAAACTTTGCTCCTCGTAAGTGGAGATAAAGAGATGGGCTCGGAAGTCGAGAGCGACAATATACAAGATATTGCAGACGAGTTAGTTCCCGGCGAGCAGGAAAGTactataataacaaaaatacgtAACAGTGATATAAATGTATTGCATTTTGTACAAACATCGAAAAGGACTGAAACACTTCATCTAATTGCTGCGGGTAAAAGCAATAATACCCTCCATCTCATAACAAAGCAGAACGAATCTTTCCCAGTTTTGACGATACCGAATCCGGAGAGTCATCTTAATTTTTCGAGTCAAATGAGCGAGAGTAATCGCGTCGAGGGTAACGGAAGTAGCGAACAAGAAGAATCCATTATAGATGAGGAAACGGCGAATGTCGACCAAGTagcccaatattttcaccaacagcagcagcatcaaGACAGCGACGAAGACGAGGAAATGGTTTGTGGTATATGTGGCGATgatttcgacgataaaaacgTACTCATGGAACACGTTAAAATTCACATATAA
- Protein Sequence
- METQDNDQAYVTFPIGGVHAAIQQNIISHEKIREPNEYTRTKVAANGLSANISMEQSDEEGEKSEVYPIYVKQEEHQRCRRRQQQPQHQHQYTSGDDESMAVEALRQLGGMYPCYEDKKMSCPNCTKIFMETDLAKHNETCESIKLSCTTCGEKFERKQDLNNHIVCHQVDRPHACRTCGNLFHSKANLQRHMSQVHQTEKPHKCTICGADFQRPSSLSNHMKIHTYVAGRAIMQSQINSNSQSAETFGKWQESELQNSSITSSPVQSNSNYDVSQVQWSVPSYNFSNDQTTTIAIGQEKIGSPQEFTVMPNGEVTQFEYAQQTSMTNQYSLSINSFGNSMDSMVKVESIPFTSESRRNYVEIEINESPSKCHTCTHCGVSFSQATALASHEKIHVAKNWTMPIECEFCDKQFQDGNHLATHQITCAKKLMQNNIEQGVPSVKWGKHACTECGKKFTTKQKMFRHQWIHRKKTHSCEICGTQFEKQNQLDEHRLSAHPGDSPFTCSECGKSFVSRQGLWEHGRTHAGSPAHFHCDTCSKTFSSRQGYLIHHRTHTGERPYGCKYCWKAFRDGGTLRKHERIHTGERPHVCPLCSRAFNQKVVLREHVRWVHAAGKNDTDFTGPPYPCPLCGAFNQDRDELCAHIVKHSDQMIAEAKAKTNNNAPKTKPSKKKSKTNCNSRRKNIGDGMVSRNEQNEALLSIAETAEEADKNNDGNKTEVHETLLLVSGDKEMGSEVESDNIQDIADELVPGEQESTIITKIRNSDINVLHFVQTSKRTETLHLIAAGKSNNTLHLITKQNESFPVLTIPNPESHLNFSSQMSESNRVEGNGSSEQEESIIDEETANVDQVAQYFHQQQQHQDSDEDEEMVCGICGDDFDDKNVLMEHVKIHI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00721445; iTF_00059630; iTF_00905585; iTF_00058133; iTF_01364857;
- 90% Identity
- iTF_00059630;
- 80% Identity
- -