Basic Information

Gene Symbol
ZNF236
Assembly
GCA_963922035.1
Location
OY998231.1:383521-389393[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 24 7.3e-05 0.007 17.2 1.0 2 23 53 74 53 74 0.98
2 24 1.4e-07 1.4e-05 25.7 1.5 1 23 93 115 93 115 0.99
3 24 3.3e-05 0.0032 18.3 0.6 1 20 121 140 121 143 0.96
4 24 8.6e-06 0.00083 20.1 0.4 1 23 149 172 149 172 0.97
5 24 0.0023 0.22 12.5 5.4 1 23 181 204 181 204 0.98
6 24 2e-06 0.0002 22.1 1.9 1 23 319 341 319 341 0.98
7 24 0.00062 0.059 14.3 1.7 1 23 347 369 347 369 0.99
8 24 0.0069 0.66 11.0 4.5 1 23 375 397 375 397 0.98
9 24 7.1e-07 6.9e-05 23.5 2.6 1 23 401 423 401 423 0.98
10 24 0.00035 0.033 15.1 3.6 1 23 478 500 478 500 0.98
11 24 0.0001 0.0099 16.7 4.6 1 23 506 528 506 528 0.99
12 24 1.8e-05 0.0018 19.1 1.3 1 23 534 556 534 556 0.98
13 24 0.00011 0.01 16.7 7.2 1 23 562 584 562 584 0.98
14 24 0.0021 0.2 12.6 2.0 2 23 897 918 896 918 0.97
15 24 0.032 3.1 8.9 3.6 2 23 945 966 944 966 0.97
16 24 0.0015 0.15 13.0 2.2 1 23 972 994 972 994 0.98
17 24 0.063 6 8.0 0.1 2 23 1001 1022 1000 1022 0.96
18 24 1e-07 1e-05 26.2 1.4 2 23 1099 1120 1098 1120 0.98
19 24 0.051 4.9 8.3 5.5 1 23 1126 1148 1126 1148 0.98
20 24 0.0011 0.11 13.4 3.9 1 23 1154 1176 1154 1176 0.97
21 24 7.3e-05 0.007 17.2 2.8 1 23 1182 1204 1182 1204 0.99
22 24 0.00025 0.024 15.5 1.9 2 23 1432 1453 1431 1453 0.97
23 24 2.4e-05 0.0023 18.7 3.3 1 23 1459 1481 1459 1481 0.98
24 24 6.3e-07 6e-05 23.7 3.0 1 23 1487 1510 1487 1510 0.96

Sequence Information

Coding Sequence
ATGACTCTCGCCGTCGACTGTGTCAATTTCGCTCTCCTACTCATTTGCTCCCaggttttttatttcgctgttGGTCTCAGCGCTCAATATTACAAGGCACAACTTGATGCACATTTGAAGCTTCACAATGAGAAGTGGACGACCGAAGATGTACGAAAGTGTAAACTGTGCAACAAGCAGTTTACACAACCCGCTCTCTACCGTCTTCATATTAGAGAACATTACAGGAGCAAAATAGTGAAACAAACGAAAAGAGGGTCAAACCACAAAACAATGTACAAATGCAAGATATGCTCGAAATCCTTCCAAAAGCCAAGCCAATTGATGCGTCATATAAGGGTGCACACTGGAGAGAAACCGTTCAAATGTACAGTCTGCACTCGAGCGTTCACCCAAAAGGGATCTCTACAGATTCACATGTGGCAGCACATCGGTGTTCGTCCGTACAGTTGCGAATTTTGCAACGCTAAATTCAGCCAAAAAGGTAATTTGAACGCTCACATCCTGAGGGTACACAACGCACCGGAGGGTGAGCCTATTTACAGCTGCACGCATTGTACGTGTGTATTCAAAAAATTGGGAAGTCTCAACGGTCACATGAAGAAAATGCACTCTAATCCAACGGAGGAACCTTCGCAAAAATGTGACAGCTCTACGGAAGCTGATATGCGAGTCACCGTCGACAATGTTATGTCCCAGTTGGCATCGCTCGACGGGAATGTTAAAAATCAAGCCGATTCTACAGATCCGGAATTAACGTCGACCTGCAAAGACGACATTCTCCAGCAGGCTTTGAAAAACAGTGGATTACCAAGCAAGACAAAAGCTGAAGAGTCGTTAAACAATAAAGCTGACGCACAGACATCGTTTGTTACACTGTTGGACAGGGCGCCCGATGGTTCATTGAGAAGGTATCTCACAATAAAACAACGGTGCATTGGAAGCATAAGATGGTACGCCTGTTCCTTCTGTCATAAAGAATTCAAAAAGCCATCGGATCTCATACGACACTTGCGAGTACATACCCAAGAAAAACCATTCAAGTGTTCATTTTGTTATCGATCGTTCGCGCTGAAGTCGACGATGATAGCCCACGAGAGGACGCATACCGGTACGAAGAAATATGCGTGCAATACATGTGAAAAGACGTTTAGTTGCCACAGTAGTCTTGTATCGCACGCGCGAACCCACGGGAAACCCCACAAGTGTGATATATGCGATAAATCGTTCAGTACGAGTTCCGTACTAAAGAGCCACATCAAGAGTCATACAAAGGGGAAGTCAAAGATATCGCCAGAAGCTGAAATTCTCGTACCGCAAATCATTCTCGAGGAACCACTCATAATCAGCGATGCTGGAAATAAAATTAGCGTTGCTCAGGTTCAATCGAAACAGAAACAGGTTTACGATAACGCTGACATTGCGAGGCCTCACAAATGTTGGGTTTGTCCAGCGGCGTTTAGAAAAATAAGTCATCTTAAGCAACATTATCGAAGGCACACCGGAGAAAGACCCTACAAGTGTCTCAAGTGTGACAGgagATTCACCTCCAACAGCGTACTCAAATCGCATTTGCACACGCACGAGGAGTCGAGACCCTACAGTTGCTCTGTTTGCAACGCAAAATTTTCGACCCAAAGTAGTATGAAGAGGCATCTGGTCACTCACAGCAACAAGAGGCCCTTCATGTGCCCCTACTGTCACAAAACCTTCAAGACGTCGGTCAATTGTCGGAAGCACATGAAGATTCATAAAACCGAATTGGCGCAACAGCAATTGGAGCAACAGAGAACGCACCGAGACGTTCGAGTCTTATCTATCAAGGAAAAAGAAGTGATGTCAGGATTGCCGGAAAATTTGACACTTGGCGAGGACATGGGAGTGACGTTTCAATCGCAAATTGCGCCCGACTTTACTCAGGCGTTTGACGATCAATTTCACGCTATTACGGATGATAAGGAGAAATCGTTTCTAACCGATGGAGGAATAACTACTCAAACAATTGACAATCagACTTTACCCGTGGTAGATACAGATAACTTAGGAACATCCCAGACCTTGCATGCTGACGAAACGGGCACTATTACGCTACCTAACTACTCCGGAGATCAAACACTCACGCCAGAGAGCATACGCGAGATAGAGGAAACGTTGAATCaacaattatttaatatcGGAATGAACGACCCAAGCTCTGTACCTCTCGAACCGAGGGATCAGCCGGTATTGAATATTATCTATGACAACGCGAAAGGACTGGACGCAGTCAACAATGCCTCTCTAAATGCCAACATCTTTCCCACGCATTTTGATACCTTTGACATGAGTCAAATAACCCTTCAAACGGACGCGGAAATTGATATGGGTATCAGCACGGCCAATTCAACAAGCATGGCAAGCATCTTACCGCGTTCGGCTCAAGAAGAGCAGCGTCTCGTTCCCGTAACGACCGGCACCAATGCGGACGATTCGCCAAATAAATCGTCTCGGCATTTGATGGTTGTAAGCTCGATGCAAACGTGTCCCGAGCTGTCGAGGCCCGTACAAGCTTGCCCAAAATATCCAAAAGTCATTGCAAAAGCTGATACGACGGACAGTGCCGAAGTTCTCAACATCGACTGTGAATCGAATCAACGAAATACGACGATCTGCCCGTCGACTAGTCCGGAACAGGAGTCAATTATATTGACATGTGATCTGTGCCACAAGCTATTTAAAAATCAACAACTTCTGGAAGGTCATCGAAAGGTTCATTCTCAGACTAACAAGATTGGACATCTAACCGAGACAAATGAACAATCGTCGATCATTCTCGAGCCAGAGTCCTTGCTCCAATGTCACATGTGCAGCAAAAAAGGTTTCACAACGGAAACATTGAAGAGCCACTTGAACACACATCGAGGTACGAAGGAATTTCAATGCAGCGCGTGTTCGTTGAGGTTTTGCTCAAATGGAGGTCTCAGCAGGCATTTAAAAATGCACGCTAATAAATCCCAATGGAACTGCTCGATGTGCTTCGAATCGTTGCCAAATGAAGGGCAGCTCAAGGAACACGCGAAAATACACGAGAACATCGGATGGAAGACCGGGTCCGCTGAACCGGATAGTTCGCAGAAGGAACCGATATCGATAAATCCCGCCGATTTCTTGGTCGTAACGACAGCGAATGGCAACACGACAGCGGATGCTTCCATCTCCGAGAAAGTTCTGATGGATACCGTAGCGGAACGCCAGATTATTAATCGTTCATCCGGCAATCCTGAATTGAACACGGAGAAGAAGGAATATACAAACAAATGTAAATACTGTCCGAAAACATTTCGAAAACCGAGCGATCTGATAAGGCATGTTCGGACGCACACAGGCGAACGACCCTATCAGTGCGAGTTCTGTAACAAAAGTTTTGCAGTTAAGTGTACACTCGATTGTCACATGAAAGTTCATTCGGGACAGAAAACGTTTTGCTGTCACGTGTGTAACAGCTTATTCGCTACTAAAGGGAGCCTCAAAGTCCATATGCGATTGCACACTGGCTCCAAGCCTTTCAGGTGTCCAATGTGCGACTTGCGCTTCAGGACTTCCGGACATAGAAAAGTTCATCAACTAACGCATATGCGAGAGCAGAAGGGTGGCGCAAAACGAAAGCCCAAGCAATTGAAGGTCGCTGCTATCGCCAATGCAGTAGCAGAGATGGAAAAAACAGTCGCGAATTCTGTCAACATCAGAGTCGAAAATGAAGAAACCTCTGTGACTGAATATCCGGATCTGGATACAATTACGATCGACACGAGCGGTGTGACAGATCAAATAACGTTCAACGCCGATGGAACTATATTAAACAACAACTCTATGCTCTCTCTCAACGAGAGTAATCAGCTCGTGGCAAATCTACACTTTCTTCTCGCTAATGGCCTTGTTACTATTCAAGCGGACGACTCTCTGTTGACTCAAACGGCTACTGAACGTGAAACGAACGTAATCGACAACGAGACTGGTGTCACCAGTCTTATCGAGCTAACGAATAGCAACCTCTGTCAaaagcaacagcaacagctacagcaacagcagcagagCACTTTTAATGGCAATTCCACAGAAAACCTCGTTATCCCGACAGCGTTGGCTGGTCTTGAAACGACCCAGCTTGACAAGCAACAGACGACGATGCAAATGAACGAATGCATGACTCTTGTACAAATGAATGCGGTTCCTACTTCCGTGATGGAGGAGAAACTCCAGGTCCAAGTACAACTTCCGAAACAATTGTTAGGAAAGGCAAGTGCCTCGAAGAAAGAATGTGATATCTGTGGCAAAACATTTATGAAACCCTGCCAAGTGGAGAGACACAAACGAATTCATACCGGTGAACGGCCGTACAAGTGCGAACTGTGCTCAAAGTCATTTGCTCAGAAAGCAACATTACAAATGCATCAGAAACACCACACAGGTGATCGACCTCATCCCTGTCCTCACTGTGATTACTCGTTCACGCAAAAAGGTAATCTTCAAACTCATCTTAAGCGGGCTCATCAGCTCGATACACTGGACGTTAAAAAATTCCGACGGGGACAACAGCAACAACTTTTGAGCGCAAAATTAATGCAGGATCATTTTGACGACGGCAGAATATTGAATTTGGATGATATATCCTTTGTTGAGTTACTAAAATAA
Protein Sequence
MTLAVDCVNFALLLICSQVFYFAVGLSAQYYKAQLDAHLKLHNEKWTTEDVRKCKLCNKQFTQPALYRLHIREHYRSKIVKQTKRGSNHKTMYKCKICSKSFQKPSQLMRHIRVHTGEKPFKCTVCTRAFTQKGSLQIHMWQHIGVRPYSCEFCNAKFSQKGNLNAHILRVHNAPEGEPIYSCTHCTCVFKKLGSLNGHMKKMHSNPTEEPSQKCDSSTEADMRVTVDNVMSQLASLDGNVKNQADSTDPELTSTCKDDILQQALKNSGLPSKTKAEESLNNKADAQTSFVTLLDRAPDGSLRRYLTIKQRCIGSIRWYACSFCHKEFKKPSDLIRHLRVHTQEKPFKCSFCYRSFALKSTMIAHERTHTGTKKYACNTCEKTFSCHSSLVSHARTHGKPHKCDICDKSFSTSSVLKSHIKSHTKGKSKISPEAEILVPQIILEEPLIISDAGNKISVAQVQSKQKQVYDNADIARPHKCWVCPAAFRKISHLKQHYRRHTGERPYKCLKCDRRFTSNSVLKSHLHTHEESRPYSCSVCNAKFSTQSSMKRHLVTHSNKRPFMCPYCHKTFKTSVNCRKHMKIHKTELAQQQLEQQRTHRDVRVLSIKEKEVMSGLPENLTLGEDMGVTFQSQIAPDFTQAFDDQFHAITDDKEKSFLTDGGITTQTIDNQTLPVVDTDNLGTSQTLHADETGTITLPNYSGDQTLTPESIREIEETLNQQLFNIGMNDPSSVPLEPRDQPVLNIIYDNAKGLDAVNNASLNANIFPTHFDTFDMSQITLQTDAEIDMGISTANSTSMASILPRSAQEEQRLVPVTTGTNADDSPNKSSRHLMVVSSMQTCPELSRPVQACPKYPKVIAKADTTDSAEVLNIDCESNQRNTTICPSTSPEQESIILTCDLCHKLFKNQQLLEGHRKVHSQTNKIGHLTETNEQSSIILEPESLLQCHMCSKKGFTTETLKSHLNTHRGTKEFQCSACSLRFCSNGGLSRHLKMHANKSQWNCSMCFESLPNEGQLKEHAKIHENIGWKTGSAEPDSSQKEPISINPADFLVVTTANGNTTADASISEKVLMDTVAERQIINRSSGNPELNTEKKEYTNKCKYCPKTFRKPSDLIRHVRTHTGERPYQCEFCNKSFAVKCTLDCHMKVHSGQKTFCCHVCNSLFATKGSLKVHMRLHTGSKPFRCPMCDLRFRTSGHRKVHQLTHMREQKGGAKRKPKQLKVAAIANAVAEMEKTVANSVNIRVENEETSVTEYPDLDTITIDTSGVTDQITFNADGTILNNNSMLSLNESNQLVANLHFLLANGLVTIQADDSLLTQTATERETNVIDNETGVTSLIELTNSNLCQKQQQQLQQQQQSTFNGNSTENLVIPTALAGLETTQLDKQQTTMQMNECMTLVQMNAVPTSVMEEKLQVQVQLPKQLLGKASASKKECDICGKTFMKPCQVERHKRIHTGERPYKCELCSKSFAQKATLQMHQKHHTGDRPHPCPHCDYSFTQKGNLQTHLKRAHQLDTLDVKKFRRGQQQQLLSAKLMQDHFDDGRILNLDDISFVELLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00905566;
90% Identity
iTF_01364829;
80% Identity
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