Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 8.2 6.5e+02 0.5 0.1 24 45 93 114 81 121 0.79

2 5 0.0023 0.18 11.9 0.0 21 51 118 148 107 150 0.83

3 5 1.2 91 3.3 0.0 21 48 146 173 143 178 0.84

4 5 3.3 2.6e+02 1.8 0.0 21 46 174 199 163 205 0.82

5 5 0.013 1 9.5 0.0 21 45 202 226 197 232 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	8.2	6.5e+02	0.5	0.1	24	45	93	114	81	121	0.79
2	5	0.0023	0.18	11.9	0.0	21	51	118	148	107	150	0.83
3	5	1.2	91	3.3	0.0	21	48	146	173	143	178	0.84
4	5	3.3	2.6e+02	1.8	0.0	21	46	174	199	163	205	0.82
5	5	0.013	1	9.5	0.0	21	45	202	226	197	232	0.89

Coding Sequence: GAGAAAAATAAGAAAGTCAATATGAATATTTGTGCAATAAAAGAAGAAAAAATCGAAATTATTGACGAATCAAAAGCAGAATTCGACAATTTTGATCAGATGGAAAAAATTGAAGAACATGAGGTGAATCTTAAATTTGAAATAAAAAAAGAAGAATTACACTCTACAATAGAATTACCAGATTTTAAAACCGAATTTCAAGATTGTGATGAAGAATTAAATTCAGAGCGAGATTCAACAAAACAGGAACCGAGTTATAAAATTATTGCCGATAAATCTTTTAAATGTAAGATTTGTTCGAAATGTTTCACACAATTCGGTCATTTAAAAGCTCATATTAGAACTCACACTGGAGAAAAACCTTTTAAATGTAAATTATGTTCGAAATGTTTCACACAATCCAGCAATTTAAAAAATCATATAAAAACTCACACTAACGAAAAACCTTTTAAATGTAAATTATGTTCGAAATGTTTCGCACAATTGGGTAGTTTAAAAAATCATATGAAAACTCACACTAACGAAAAACCTTTTAAATGCAAATTTTGTTCGAAATGTTTCACATATTCTGATAGTCTAAAAATTCATATTAGAACTCACACTAACGAAAAACCTTTTAAATGTGAAATATGTTTAAAAGATTTTACACATTCAAGTAATTTAAAAAAACACATTAGAACTCACATTGATAAAAACGCTAAGTAA
Protein Sequence: EKNKKVNMNICAIKEEKIEIIDESKAEFDNFDQMEKIEEHEVNLKFEIKKEELHSTIELPDFKTEFQDCDEELNSERDSTKQEPSYKIIADKSFKCKICSKCFTQFGHLKAHIRTHTGEKPFKCKLCSKCFTQSSNLKNHIKTHTNEKPFKCKLCSKCFAQLGSLKNHMKTHTNEKPFKCKFCSKCFTYSDSLKIHIRTHTNEKPFKCEICLKDFTHSSNLKKHIRTHIDKNAK

Sequence clustering based on sequence similarity using MMseqs2