Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.23 18 5.5 0.1 21 46 158 183 150 187 0.90

2 6 1.5 1.2e+02 2.9 0.3 22 47 187 212 182 217 0.80

3 6 0.042 3.3 7.9 0.1 21 52 214 245 210 247 0.88

4 6 1.3 1e+02 3.1 0.0 21 44 242 265 240 268 0.90

5 6 0.0088 0.69 10.1 0.1 21 48 270 297 265 301 0.86

6 6 0.017 1.3 9.2 0.1 21 48 298 325 296 328 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.23	18	5.5	0.1	21	46	158	183	150	187	0.90
2	6	1.5	1.2e+02	2.9	0.3	22	47	187	212	182	217	0.80
3	6	0.042	3.3	7.9	0.1	21	52	214	245	210	247	0.88
4	6	1.3	1e+02	3.1	0.0	21	44	242	265	240	268	0.90
5	6	0.0088	0.69	10.1	0.1	21	48	270	297	265	301	0.86
6	6	0.017	1.3	9.2	0.1	21	48	298	325	296	328	0.91

Coding Sequence: ATGGACTTTACTGATCCAGAGAAAGATGTATGTTCAAAAATTGAGTTGCGACAAAATATTAGTGATTCAGCAATTGTTAATGATAAAGAACCTTTTTGGGATATAAAAACTGAACCTTCTTACTTCTGTTGTGTTTCGATTGAAAATGGTAATGAGAGAGATATTAAGACCGAAGATGTTTGTTCAACAGGTGAAATCGGACAAGATATTAGTGATCCTCTGGCTATTAAAATCACTGATATCGAAATTAAGAAAGAACAGACTGATTCTGACTTACCTACACTAAAAGATGAAGATAGTGAAATTATTGATAGGAATAGTAAATACCAGTGTTCATTCTGCAAAAAAGATTTTCTATCTGCAGAAGAACAATCTGATCATAACTGTAAAAGAAATTCCGAAATGTGTTGTTATTGTTTATATACTTCCTCTAACAAATCTGATTTAAAGAGGCATATCAGAATTCACACTGGAGAAAAACCATATAAATGCGATGTGTGTTCGTACAGTTTTTCACAATTATCGAATTTAAAGACACATATGAGCATTCATACTGGAGAACGGTCGTTTAAATGTGAAATTTGTTTATGCACATTTTCACGAAAATCGAGTTTAAAAAGACACACAAGAATTCATACCGGAGAAAAACCATATAAATGTGATATTTGTTCACATACTTGTACGGACGAATCAAATTTAAAAAGTCACCTGCGAGTTCATACTGGAGAAAAACCATTTATCTGTGAAGTGTGTTCATGCAGTTTTTCACAAACATGGAAATTAAAAATGCACATGAGAACTCACACGGGAGAAAAACCATATAAATGTGAAATTTGTTCGTACACTTTTTCACAAACTTCTAGTTTAAAGAGGCATATAAGAATCCACACTGGAGAAAAACCATTTAAATGTGAAGTTTGTTCTCTCACATTTACACAACAAGCTACTTTAAGAAAACATTTGTTAAGAAAACATCTGATAATTCAGACTGAAGAAAACTCATAG
Protein Sequence: MDFTDPEKDVCSKIELRQNISDSAIVNDKEPFWDIKTEPSYFCCVSIENGNERDIKTEDVCSTGEIGQDISDPLAIKITDIEIKKEQTDSDLPTLKDEDSEIIDRNSKYQCSFCKKDFLSAEEQSDHNCKRNSEMCCYCLYTSSNKSDLKRHIRIHTGEKPYKCDVCSYSFSQLSNLKTHMSIHTGERSFKCEICLCTFSRKSSLKRHTRIHTGEKPYKCDICSHTCTDESNLKSHLRVHTGEKPFICEVCSCSFSQTWKLKMHMRTHTGEKPYKCEICSYTFSQTSSLKRHIRIHTGEKPFKCEVCSLTFTQQATLRKHLLRKHLIIQTEENS

Sequence clustering based on sequence similarity using MMseqs2