Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 3.4 2.7e+02 1.8 0.1 26 46 132 152 128 157 0.88

2 6 0.0057 0.45 10.7 0.6 22 48 210 236 202 240 0.84

3 6 1.1 85 3.4 0.0 21 45 237 261 235 264 0.87

4 6 0.09 7.1 6.8 0.1 21 48 265 292 262 296 0.86

5 6 0.066 5.2 7.3 0.2 21 48 293 320 288 324 0.86

6 6 0.056 4.4 7.5 0.1 21 46 321 346 318 351 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	3.4	2.7e+02	1.8	0.1	26	46	132	152	128	157	0.88
2	6	0.0057	0.45	10.7	0.6	22	48	210	236	202	240	0.84
3	6	1.1	85	3.4	0.0	21	45	237	261	235	264	0.87
4	6	0.09	7.1	6.8	0.1	21	48	265	292	262	296	0.86
5	6	0.066	5.2	7.3	0.2	21	48	293	320	288	324	0.86
6	6	0.056	4.4	7.5	0.1	21	46	321	346	318	351	0.90

Coding Sequence: ATGGATGGTAACAAAGAAACATCAAATCCCTTAATGAATAATGAAATCGAAAGTAATCCTAAAGAATTGTTATCTACGATTAAAACCGAAGAAATTGAAATTGAAGAATGTAAACTCGAATTCGAGAACTTGCATCAGATAATGAAAAGGGAAAGTTCTGTCGAAAAAGTTTTTTCAACTAAAAGCGGTGTTGTGTTAATAGGTTTCCCATCTGCGACAAAAAAATGGCATCATCATTTTGGGAAATTCAATGGAACATGTTTGTATTGTGGACAATTCTTTTGTGATAAATTGTTATTTTTATACCATTTTAGTATTTACCACTTTATAGTTAAATCTGTTGATTTGAGAATGAATAATTCTGCTATTGAACATATTGGACAAATATCCTTTAAATGCAAAATTTGTTCAAAATGTTTTAAAAACCAAAGTAATTTAAAAGAGCATAATAGACTTCACACTGGTGAAAAATTATTTAAATGTGAATATTGTTCGAAATGTTTCACAAAATACAAGCGTTTAAAAATGCATGTTAGAATTCACACTAACGAGAAATTTAAATGTGATATTTCTTCACAATATTTCCGAAAATTTGATGATTTGAAAAGGCATTTTATGATTCACACTGAAAAATCGCCAAGATGTGAAATTTGTTCAAAATGCTTCCGGCAACAAGGTAATTTAAAAAAGCATATTAGAATTCACACTGGTGAAAAACCTTTTAAATGTGAAATTTGTTCAAAATGTTTCACAGGGCAAAGTGATTTAAATCGACATGTTAAAACTCATACTGGTGAAAAACCTTTTAAATGTGAAATTTGTTCAAAATGTTTTGCAGACCATAGTAATTTAAAACAACATATTAGAATTCACACTGGTGAAAAACCTTTTAAATGTGAAATTTGTTCAAAGTGTTTCACAGAACAAAGTAATTTAAAACAACATATTAGAATTCACACTGGTGAGAAACCTTTTGAATGTAAAGTTTGTTTAAAATGTTTCACACGATCCAGTAATTTAAAAACTCATATTAGAATTCACACTGACGAGAAAGCATTTTAA
Protein Sequence: MDGNKETSNPLMNNEIESNPKELLSTIKTEEIEIEECKLEFENLHQIMKRESSVEKVFSTKSGVVLIGFPSATKKWHHHFGKFNGTCLYCGQFFCDKLLFLYHFSIYHFIVKSVDLRMNNSAIEHIGQISFKCKICSKCFKNQSNLKEHNRLHTGEKLFKCEYCSKCFTKYKRLKMHVRIHTNEKFKCDISSQYFRKFDDLKRHFMIHTEKSPRCEICSKCFRQQGNLKKHIRIHTGEKPFKCEICSKCFTGQSDLNRHVKTHTGEKPFKCEICSKCFADHSNLKQHIRIHTGEKPFKCEICSKCFTEQSNLKQHIRIHTGEKPFECKVCLKCFTRSSNLKTHIRIHTDEKAF

Sequence clustering based on sequence similarity using MMseqs2