Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.26 20 5.4 0.2 26 51 92 117 77 119 0.88

2 7 0.07 5.5 7.2 0.2 22 44 116 138 112 142 0.90

3 7 0.032 2.5 8.3 0.2 21 46 143 168 139 174 0.85

4 7 0.058 4.6 7.4 0.2 22 44 172 194 166 199 0.89

5 7 0.032 2.6 8.2 0.2 21 46 199 224 195 230 0.85

6 7 0.047 3.7 7.7 0.3 22 44 228 250 223 254 0.89

7 7 0.27 22 5.3 0.3 21 46 255 280 251 287 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.26	20	5.4	0.2	26	51	92	117	77	119	0.88
2	7	0.07	5.5	7.2	0.2	22	44	116	138	112	142	0.90
3	7	0.032	2.5	8.3	0.2	21	46	143	168	139	174	0.85
4	7	0.058	4.6	7.4	0.2	22	44	172	194	166	199	0.89
5	7	0.032	2.6	8.2	0.2	21	46	199	224	195	230	0.85
6	7	0.047	3.7	7.7	0.3	22	44	228	250	223	254	0.89
7	7	0.27	22	5.3	0.3	21	46	255	280	251	287	0.85

Coding Sequence: ATGTTTTACATATATTTTTTTCTACTATTTATTTTTAGCATTATTACCATTGATACGAGATTATATATTTCAGGTTTTCTACCAGCGCCAAAAAAGTATCAACCTCACTTTGGGAAATTTTATGGAACATGTTCCTTTTGTGGACAATTTTTCTCTGATAAATTGCTATTTTTAAACCATTTTTATATATACCACTTTTTAGTTAATTCCAAAAAATCTGTTAACTTAAGAAGGAATAATTCTGATAAAAAACATATTAGACAAATGTTCTTTAAATGCGAAATTTGTACAAAATGTTTCACACAATCCAGTGATTTAAAAAGCCATATTAGAATTCACACTGACAAGAAACCTTTTAAATGTAAAATTTGTTTAAAATGTTTCCGAAGAGCAGGTGATTTAAATAGACATATTAGAACTCACACTGGTGAAAAACCTTTTAGATGTGAAATTTGTTCAAAATGTTTCACACAATCCAGTAGCTTAAAAGCTCATATTAGAACTCACACTGGTAAAAAACCTTTTAAATGTAAAATTTGTTTAAAATGTTTCCGAAGAGCAGGTGATTTAAATAGACATATTAGAACTCACACTGGTGAAAAACCTTTTAGATGTGAAATTTGTTCAAAATGTTTCACACAATCCAGTAGCTTAAAAGCTCATATTAGAACTCACACTGGTAAAAAACCTTTTAAATGTAAAATTTGTTTAAAATGTTTCCGAAATGCAAGTGATTTAAATAGACATATTAGAACTCACACTGGTGAAAAACCTTTTAGATGTGAAATTTGTTCAAAATGTTTCACACGATCCAGTAGCTTAAAAACTCATATTAGAACTCACACTGGTGAAAAACCTTTTTCACAATTCACAATTCAATTTAATATATAA
Protein Sequence: MFYIYFFLLFIFSIITIDTRLYISGFLPAPKKYQPHFGKFYGTCSFCGQFFSDKLLFLNHFYIYHFLVNSKKSVNLRRNNSDKKHIRQMFFKCEICTKCFTQSSDLKSHIRIHTDKKPFKCKICLKCFRRAGDLNRHIRTHTGEKPFRCEICSKCFTQSSSLKAHIRTHTGKKPFKCKICLKCFRRAGDLNRHIRTHTGEKPFRCEICSKCFTQSSSLKAHIRTHTGKKPFKCKICLKCFRNASDLNRHIRTHTGEKPFRCEICSKCFTRSSSLKTHIRTHTGEKPFSQFTIQFNI

Sequence clustering based on sequence similarity using MMseqs2