Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.63 50 4.1 0.7 26 47 88 109 78 114 0.83

2 6 0.044 3.5 7.8 0.0 21 44 111 134 107 138 0.90

3 6 0.018 1.4 9.0 0.0 21 46 139 164 134 171 0.83

4 6 0.062 4.9 7.3 0.3 21 46 167 192 163 200 0.83

5 6 1.5 1.2e+02 2.9 0.1 20 43 208 231 192 236 0.71

6 6 0.14 11 6.2 0.0 21 45 237 261 226 263 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.63	50	4.1	0.7	26	47	88	109	78	114	0.83
2	6	0.044	3.5	7.8	0.0	21	44	111	134	107	138	0.90
3	6	0.018	1.4	9.0	0.0	21	46	139	164	134	171	0.83
4	6	0.062	4.9	7.3	0.3	21	46	167	192	163	200	0.83
5	6	1.5	1.2e+02	2.9	0.1	20	43	208	231	192	236	0.71
6	6	0.14	11	6.2	0.0	21	45	237	261	226	263	0.87

Coding Sequence: ATGAATATTTGTGCAATAAAAGAAGAAAAAATCGAAATTATTGACGAATCAAAACCAGAATTCGACAATTTTGATCAGATGGAAAAAATTGAAGAACATGAGGTGAATGTTGAATTTGAAATTAAAAAAGAAGAATTACACTCTACAATAGATTTACCGGATTTTAAAATCGAATTTCAAGATTCTGATGAAGAATTAAATTCAGAGCGAGATTCAACAAAACATAATTCGAGTTATAAAAATATTGACGATAAATCTTTTAAATGTAAAATTTGTTCGAAATGTTTCACAAAATCCTGTAATTTAAAATGTCATATTAGAACTCACACTAACGAGAAACCTTTTAAATGTAAGATTTGTTCGAAATATTTCACAGTATCCGGTAATTTAAAAAAGCACATTAGAAGTCACACTAATGAGAAACCTTTTAAATGTAATATTTGTTCGAAATATTTCATAGACTCCAGTACTTTAAAAAGGCATATTAGAACTCACACTGGAGAAAAACCTTTTAAATGTGAAATTTGTTCGAAATGTTTCACACAATCAAGTAGTTTAAAATATCATAGTAGAACTCACACTAACGAGAAACCAAGTAGTTTAAAATATATTAGAACTCACACTAACGAGAAACCATTTAAATGTAAAATATGTTCGAAATCTTTCACACAATTGGGTCATGTAAAAACTCATATTAGAACTCACACTGGAGAAGAACCTTTTAAATGTAAATTATGTTCGAAATGTTTCACAGAATCCGGTAGTTTAAAAAGGCATATAAAAACTCACTAA
Protein Sequence: MNICAIKEEKIEIIDESKPEFDNFDQMEKIEEHEVNVEFEIKKEELHSTIDLPDFKIEFQDSDEELNSERDSTKHNSSYKNIDDKSFKCKICSKCFTKSCNLKCHIRTHTNEKPFKCKICSKYFTVSGNLKKHIRSHTNEKPFKCNICSKYFIDSSTLKRHIRTHTGEKPFKCEICSKCFTQSSSLKYHSRTHTNEKPSSLKYIRTHTNEKPFKCKICSKSFTQLGHVKTHIRTHTGEEPFKCKLCSKCFTESGSLKRHIKTH

Sequence clustering based on sequence similarity using MMseqs2