Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.28 22 5.2 0.0 26 45 88 107 74 110 0.86

2 6 0.052 4.1 7.6 0.0 21 45 111 135 107 139 0.91

3 6 0.29 23 5.2 0.0 22 46 140 164 136 170 0.86

4 6 0.61 48 4.2 0.1 22 44 168 190 165 194 0.86

5 6 0.064 5.1 7.3 0.0 21 47 195 221 191 226 0.86

6 6 1.4 1.1e+02 3.0 0.0 21 45 223 247 220 253 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.28	22	5.2	0.0	26	45	88	107	74	110	0.86
2	6	0.052	4.1	7.6	0.0	21	45	111	135	107	139	0.91
3	6	0.29	23	5.2	0.0	22	46	140	164	136	170	0.86
4	6	0.61	48	4.2	0.1	22	44	168	190	165	194	0.86
5	6	0.064	5.1	7.3	0.0	21	47	195	221	191	226	0.86
6	6	1.4	1.1e+02	3.0	0.0	21	45	223	247	220	253	0.89

Coding Sequence: ATGGACATTTCTGTCATTAAACAAGAAGAAATAGAAATTTTTGATGAACCAAAACCCGAATTGCATTGTTTCGATCAGATGGAATTAATTGAAGAACATGAGGTGAATATTGAATTTGAAATTAAAAAAGAAGAATTACACTCTACAATAGATTTACCGGATTTTAAAATCGAATTTCAAGATTCTGATGAAGAATTAAATTCAGAACGAGATTCAACAAAACAGGAACCGAGTTATAAAAATATTGCCGGTAAATCTTTTAAATGTAAAATTTGTTCGAAATATTTCACAAAATCCGGTAATTTAAAAAAGCACATTAAAACTCACACTGGGGAAAAACCTTTTAAATGTGAAATTTGTTCGAAATATTTCACAGAATCCGGTAATTTAAAAACGCACATTAAAACTCACACTGGGGAAAAACGTTTTAAATGTGAAATTTGTTCGAAATGTTTCACACAATCTAGTAGTTTAAAATCGCATGTTAAAATTCACACTGGCGAGAAAGATTTTAAATGTGAAATTTGTTCACAATGTTTTTCACACTCCGGTAGTTTAAAAAGACATATTAGAACTCACACTAACGAAAAACCTTTTAAATGTAAAGTATGTTCGAAATGTTTCACAGCATCCGGTAATTTAAAATCTCATATTAATACTCACACTGGAGAAAAACCTTTTAAATGTAAATTATGTTCGAAATGTTTCACACATTCCAGTAGTTTAAAAAGTCATATTAAAACTCACACTAACGAAAAAACCTTTTAA
Protein Sequence: MDISVIKQEEIEIFDEPKPELHCFDQMELIEEHEVNIEFEIKKEELHSTIDLPDFKIEFQDSDEELNSERDSTKQEPSYKNIAGKSFKCKICSKYFTKSGNLKKHIKTHTGEKPFKCEICSKYFTESGNLKTHIKTHTGEKRFKCEICSKCFTQSSSLKSHVKIHTGEKDFKCEICSQCFSHSGSLKRHIRTHTNEKPFKCKVCSKCFTASGNLKSHINTHTGEKPFKCKLCSKCFTHSSSLKSHIKTHTNEKTF

Sequence clustering based on sequence similarity using MMseqs2