Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.016 1.3 9.2 0.1 21 45 132 156 127 160 0.90

2 6 0.19 15 5.8 0.0 21 52 160 191 157 192 0.88

3 6 0.22 17 5.6 0.1 21 44 188 211 184 215 0.91

4 6 0.003 0.24 11.6 0.1 21 45 216 240 212 247 0.87

5 6 0.0089 0.7 10.0 0.0 22 52 245 275 240 276 0.89

6 6 1.8 1.4e+02 2.7 0.0 23 45 302 324 289 330 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.016	1.3	9.2	0.1	21	45	132	156	127	160	0.90
2	6	0.19	15	5.8	0.0	21	52	160	191	157	192	0.88
3	6	0.22	17	5.6	0.1	21	44	188	211	184	215	0.91
4	6	0.003	0.24	11.6	0.1	21	45	216	240	212	247	0.87
5	6	0.0089	0.7	10.0	0.0	22	52	245	275	240	276	0.89
6	6	1.8	1.4e+02	2.7	0.0	23	45	302	324	289	330	0.87

Coding Sequence: ATGGATTTAACCAAAGAAAAACTAGAAGACGTAATTAAAACAGAAGAAATTGAAATTTTCGATGAATTTGGTGAGAATAGTGGAATTATTAAAAAAGAAGAATTAAAAGAATTAAAAGTCGAATTAAATTATTTCGATAACATCGAAATAATTGAAGTACATAAGATGAATGTTGAATTTGAAATGAAAAAAGAAGAATTACACTCTACAATAGATTTACCGGATTTTAAAATCGAATTTCAAGATTCTGATGAAGAATTAAATTCAGAGCGAGATTCAACAAAACAGGAACCGAGTTATAAAAATATTACCGATAAATCTTTTAAATGTAAAATTTGTTCGAAATGTTTCACAACATCCAGTCATTTAAAAGGTCATATTAGAACTCACACTGGAGAAAAACCTTTTAAATGTAAATTATGTTCGAAATGTTTCTCACAATCCTGTAATTTAAAAAATCATATTAAAACTCACACTGGAGAAAAACCTTTTAAATGTAAAATATGTTCGAAATGTTTCACAACATCCAGTCATTTAAAAGATCATATTAGAATTCACACTAACGAAAAACCTTTTAAATGTAAATTATGTTCGAAATGTTTCACACAATCAAGTAGTTTAAAATCTCATATTAGAACTCACACTGACGAGAAACCTTTTAAATGTAATATTTGTTCGAAATATTTCACACAATCCTGTAATTTAAAAAATCATATTAAAACTCACATTGGAGAAAAACCTTTTAAATGTAAAATATGTTCGAAATGTTTCACAAAATCCAGTAATTTAAAAGATCATATTAGAATTCACACTAACGAAAAACCTTTTAAATGTAAAATTTGTTCGAAATGTTTCACACTTTTTGATACTTTAAAAAATCATAATAAAACTCACACTGGGGGAAAACCTTTTAAATGTAAATTATGTTTCGAAATCTTTCACACAATTCGGTCATTTAAAAATCATATTAAAACTCATACTAACGAAAAAACCTTTTAA
Protein Sequence: MDLTKEKLEDVIKTEEIEIFDEFGENSGIIKKEELKELKVELNYFDNIEIIEVHKMNVEFEMKKEELHSTIDLPDFKIEFQDSDEELNSERDSTKQEPSYKNITDKSFKCKICSKCFTTSSHLKGHIRTHTGEKPFKCKLCSKCFSQSCNLKNHIKTHTGEKPFKCKICSKCFTTSSHLKDHIRIHTNEKPFKCKLCSKCFTQSSSLKSHIRTHTDEKPFKCNICSKYFTQSCNLKNHIKTHIGEKPFKCKICSKCFTKSSNLKDHIRIHTNEKPFKCKICSKCFTLFDTLKNHNKTHTGGKPFKCKLCFEIFHTIRSFKNHIKTHTNEKTF

Sequence clustering based on sequence similarity using MMseqs2