Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.24 19 5.4 0.3 23 46 45 68 33 76 0.77

2 8 0.1 8 6.7 0.1 26 44 76 94 71 99 0.90

3 8 0.005 0.4 10.8 0.0 22 52 100 130 96 131 0.89

4 8 9.6 7.6e+02 0.3 0.0 21 45 127 151 125 157 0.87

5 8 1.9 1.5e+02 2.6 0.0 21 47 211 237 203 243 0.84

6 8 4 3.2e+02 1.5 0.0 21 44 239 262 235 266 0.89

7 8 0.012 0.92 9.7 0.0 21 47 267 293 256 298 0.83

8 8 0.0016 0.13 12.4 0.2 21 45 295 319 290 321 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.24	19	5.4	0.3	23	46	45	68	33	76	0.77
2	8	0.1	8	6.7	0.1	26	44	76	94	71	99	0.90
3	8	0.005	0.4	10.8	0.0	22	52	100	130	96	131	0.89
4	8	9.6	7.6e+02	0.3	0.0	21	45	127	151	125	157	0.87
5	8	1.9	1.5e+02	2.6	0.0	21	47	211	237	203	243	0.84
6	8	4	3.2e+02	1.5	0.0	21	44	239	262	235	266	0.89
7	8	0.012	0.92	9.7	0.0	21	47	267	293	256	298	0.83
8	8	0.0016	0.13	12.4	0.2	21	45	295	319	290	321	0.90

Coding Sequence: ATGAAAAAAGAAGAATTACACTCTACAATAGATTTACCGGATTTTAAAATCGAATCTCAAGATTTTGATGAAGAATTAAATTCAGAGCGAGATTCAACAAAACAGGAACCGAATTATAAAAATATTGACGATAAATCTTTTAAATGTAAAATTTGTTCGAAATGTTTTACAAAATCTATTAGTTTAAAAAGACATATTAGAATTCATACTAACAAGAAACATTTTAAATGTAAGATTTGTTCGAAATGTTTCACACAATCTAGTAATTTAAAAACTCATATTAGAACTCACATTGGAGAAAAACCTTTTAAATGTAAGATTTGTTCGAAATGTTTCACAGAATCCGGTAATTTAAAAAAGCACATTAGAATTCACACTAATGAGAAACCTTTTAAATGTGAAAATTGTTCAAAATGTTTCAAACTTTTTGATAGTTTAAAAAGGCATATTAAAACTCACACTGGACAAAAACTTTTTAAATGTGAAAATTGTTCGAAATGTTTCAAAGAATCCACTCATTTAAAAGATCATATTAGAATTCACACTAACAAAAAACATTTTAAATGTGAAATTTGTTCGAAATGTTTCACAACATCCAGTTATTTAAAATGTCATATTAGAACTCACACTAACGAGAAACCTTTTAAATGTAATATTTTTTCGAAATATTTCACACAATCCGGTCATTTAAAAAATCATATTAAAACTCACACTGGAGAAAAACCTTTTAAATGTAAGAGTTGTTCGAAATGTTTCACAGAATCCGGTAAATTAAAAAAGCATATTAGAACTCACACAGGCGAGAAACCTTTTAAATGTAATATTTGTTTGAAATATTTCACACACTCCAGTACTTTAAAAAGGCATATTAGAACTCACACGAACGAAAAACCATTTAAATGTGAAATTTGTTCGAAATATTTTAAACAATCCCGTTGTTTAAAAAATCATATAAAAACTCACTAA
Protein Sequence: MKKEELHSTIDLPDFKIESQDFDEELNSERDSTKQEPNYKNIDDKSFKCKICSKCFTKSISLKRHIRIHTNKKHFKCKICSKCFTQSSNLKTHIRTHIGEKPFKCKICSKCFTESGNLKKHIRIHTNEKPFKCENCSKCFKLFDSLKRHIKTHTGQKLFKCENCSKCFKESTHLKDHIRIHTNKKHFKCEICSKCFTTSSYLKCHIRTHTNEKPFKCNIFSKYFTQSGHLKNHIKTHTGEKPFKCKSCSKCFTESGKLKKHIRTHTGEKPFKCNICLKYFTHSSTLKRHIRTHTNEKPFKCEICSKYFKQSRCLKNHIKTH

Sequence clustering based on sequence similarity using MMseqs2