Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.0047 0.37 10.9 0.3 14 44 77 108 61 112 0.84

2 6 0.0036 0.29 11.3 0.1 20 52 112 144 109 145 0.87

3 6 0.28 22 5.2 0.1 21 44 141 164 137 167 0.89

4 6 0.0055 0.43 10.7 0.0 21 45 169 193 164 200 0.84

5 6 0.36 28 4.9 0.1 21 47 197 223 193 228 0.85

6 6 0.18 14 5.9 0.1 21 46 225 250 221 257 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.0047	0.37	10.9	0.3	14	44	77	108	61	112	0.84
2	6	0.0036	0.29	11.3	0.1	20	52	112	144	109	145	0.87
3	6	0.28	22	5.2	0.1	21	44	141	164	137	167	0.89
4	6	0.0055	0.43	10.7	0.0	21	45	169	193	164	200	0.84
5	6	0.36	28	4.9	0.1	21	47	197	223	193	228	0.85
6	6	0.18	14	5.9	0.1	21	46	225	250	221	257	0.86

Coding Sequence: ATGTATTCTAGGAAAAAACGTTTCCAATCTTCGACCAGAAAATGGCAACCTCACTTTGGGAAATTCCATGGAACATGTTCGTGCTGTGGACGATTTTTCTGTGATAAATTACTATTTTTAAACCATTTTTATATTTACCACTTTGTTGTTAATTGTAAAAAAAGTGTTAATTTGAGAAGGAAAAATGCTACTACAAAACACATTAACCTACAAGATTTTGGTGATTTAAAGCAACAGATGAGGACTCACAGTGGACAAAAATCCTTTAACTGTGAAATTTGTTTAAAATGTTTTACACAATCCGAACATTTAAAAAGGCATATTAGAACTCACAGTAGTGAAAAATCTTTTAAATGTAACATTTGTTCAAAATGTTTCACAGAACAAAATAATCTAAAACGTCATATTAAAATGCACACTGCTGAGAAACCTTTTAAATGTGAAATTTGCTCAAAATGTTTTATACGATCCAATGATTTAAAAATGCATATTAGAAGTCACACTGGTGAAAAACCTTTTAAATGTGAAATTTGTTTTAAAAGTTTTACACAATCCGGTATTTTAAAGAAGCATATTGGAACTCACACTGGTGAAAAACCTTTCAGATGTGAAATTTGTTCAAAATGTTTCACACAAAATGGTCATTTACAAATGCATGTTAGAATTCATACTGACGAAAAACCTTTTAAATGTAAAGTTTGTTCAAAATGTTTCATACAATCCGGTCATTTAAAAACGCATATTAGAACTCACACTGGTGAAAAACCTTTTAGATGTGAAGTTTTGTTCAAAATGTTTCACAGGAAATGA
Protein Sequence: MYSRKKRFQSSTRKWQPHFGKFHGTCSCCGRFFCDKLLFLNHFYIYHFVVNCKKSVNLRRKNATTKHINLQDFGDLKQQMRTHSGQKSFNCEICLKCFTQSEHLKRHIRTHSSEKSFKCNICSKCFTEQNNLKRHIKMHTAEKPFKCEICSKCFIRSNDLKMHIRSHTGEKPFKCEICFKSFTQSGILKKHIGTHTGEKPFRCEICSKCFTQNGHLQMHVRIHTDEKPFKCKVCSKCFIQSGHLKTHIRTHTGEKPFRCEVLFKMFHRK

Sequence clustering based on sequence similarity using MMseqs2