Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.017 1.3 9.2 0.0 21 46 17 42 9 49 0.85

2 7 3.8 3e+02 1.6 0.0 21 46 45 70 40 76 0.82

3 7 1.1 85 3.4 0.1 21 44 73 96 62 100 0.85

4 7 0.0038 0.3 11.2 0.2 15 44 94 124 88 128 0.82

5 7 0.0021 0.17 12.0 0.1 21 52 129 160 125 161 0.86

6 7 0.67 53 4.0 0.1 22 45 158 181 153 188 0.87

7 7 0.089 7.1 6.8 0.1 20 46 212 238 203 246 0.82

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.017	1.3	9.2	0.0	21	46	17	42	9	49	0.85
2	7	3.8	3e+02	1.6	0.0	21	46	45	70	40	76	0.82
3	7	1.1	85	3.4	0.1	21	44	73	96	62	100	0.85
4	7	0.0038	0.3	11.2	0.2	15	44	94	124	88	128	0.82
5	7	0.0021	0.17	12.0	0.1	21	52	129	160	125	161	0.86
6	7	0.67	53	4.0	0.1	22	45	158	181	153	188	0.87
7	7	0.089	7.1	6.8	0.1	20	46	212	238	203	246	0.82

Coding Sequence: ATGTTTCACACAATCCGGTATTTTAAAAATCATATTAAAAGTCACACAGGAGAAAAACCTTTTAAATGTAAATTATGTTCGAAATCTTTCACACAATCCGGTAATTTAAAATATCATATTAAAAGTCACACTGGAGAAAAACCTTTTAAATGTAAATTTTGTTCGAAATTTTTCACAGCATTCGGTAGTTTAAAAAGGCATATTAGAACTCACACTAACGAGAAACCTTTTAAATGTAAATTATGTTCGAAATGTTTCACAGAATCCGGTAAATTAAAAAATCACATTAGAAGTCACACTAATGAGAAACCTTTTAAATGTAAATTATGTTCGAAATGTTTCACACAATCCAGTAATTTAAAATGTCATATTAGAACTCACACTGGAGAAAAACCTTTTAATTGTAAATTATGTTCGAAATGTTTCACACAATCCAATAATTTAAAAAATCATATGAAAACTCACACTAACCAAAAACCATTTAAATGTAAATTATGTTCGAAATGTTTCACAGCATCCGGTAGTTTAAAAAGGCATATTAGAACTCACGCTAACGAGAAATCTTTTAAATGTGAAAATTGTTCAAAATGTTTCACACTTTTTGAATCATTAAAAAAGCATAATAGAACTCACACTGGCGAGAGACCTTTTAAATGTAAAATATGTTCGAAATCTTTCACACAATCCATTATTTTAAAATCTCATATTAGCACTCACACTGGAGAAAAACCTTTTAAATGTAAATTATGTTCGAATTGTTTTCACAAAATCCAGTAA
Protein Sequence: MFHTIRYFKNHIKSHTGEKPFKCKLCSKSFTQSGNLKYHIKSHTGEKPFKCKFCSKFFTAFGSLKRHIRTHTNEKPFKCKLCSKCFTESGKLKNHIRSHTNEKPFKCKLCSKCFTQSSNLKCHIRTHTGEKPFNCKLCSKCFTQSNNLKNHMKTHTNQKPFKCKLCSKCFTASGSLKRHIRTHANEKSFKCENCSKCFTLFESLKKHNRTHTGERPFKCKICSKSFTQSIILKSHISTHTGEKPFKCKLCSNCFHKIQ

Sequence clustering based on sequence similarity using MMseqs2