Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.11 9 6.5 0.2 15 44 66 95 61 99 0.86

2 8 0.0026 0.2 11.8 0.0 21 52 100 131 96 132 0.89

3 8 0.073 5.8 7.1 0.1 21 46 128 153 126 159 0.87

4 8 0.44 35 4.6 0.1 21 45 156 180 152 186 0.90

5 8 0.1 8 6.7 0.0 22 48 185 211 180 217 0.83

6 8 1.4 1.1e+02 3.0 0.1 21 46 212 237 208 240 0.87

7 8 0.15 12 6.1 0.2 21 44 240 263 237 267 0.91

8 8 0.21 17 5.6 0.0 21 44 268 291 264 295 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.11	9	6.5	0.2	15	44	66	95	61	99	0.86
2	8	0.0026	0.2	11.8	0.0	21	52	100	131	96	132	0.89
3	8	0.073	5.8	7.1	0.1	21	46	128	153	126	159	0.87
4	8	0.44	35	4.6	0.1	21	45	156	180	152	186	0.90
5	8	0.1	8	6.7	0.0	22	48	185	211	180	217	0.83
6	8	1.4	1.1e+02	3.0	0.1	21	46	212	237	208	240	0.87
7	8	0.15	12	6.1	0.2	21	44	240	263	237	267	0.91
8	8	0.21	17	5.6	0.0	21	44	268	291	264	295	0.90

Coding Sequence: ATGAATATTTCTGCAATAAAAGAAGAAAAAATTGAAATTATTGACGAATCAAAACCAGAATTCGATTATTTTGATCAGATGGAAAAAATTGAAGAACATGAATTTGAAATTAAAAAAGATTTACAGGATTTTAAAATCAAATTTCAAGATTGTGATGAAGAATTAAATTCTGAGCGAGATTCAACAAAACAGGAACCGAATTATAAAAATATTAGCGATAAATCTTTTAAATGTAAAATTTGTTCGAAATGTTTCACAAAATCCTGTAATTTAAAATCTCATATTAGAACTCACACTAACGAAAAACCTTTTAAATGTAAATTATGTTCGAAATGTTTCACACAATCCGGTAATTTAAAAAATCATATTAAAATTCACACTAACGAGAAACCTTTTAAATGTAAATTTTGTTTGAAATGTTTCACAAAATCCGAACATTTAAAAAGACACATTAGAACTCACACTGGAGAAAAACCTTTTAAATGTAACAGTTGTTCGAAATGTTTCACAGAATCCTGTAATTTAAAAAATCATATTAAAACTCACATTAACGAAAAATCTTTTAAATGTGAAATTTGTTCGAAATGTTTCACAGAATCCGGTAATTTAAAAAAACACATTAGAACTCACACTAACGAGAAACCTTTTAAATGTGAAAATTGTTCAAAATGTTTCACACTTTTTGATAATTTAAAAAGGCATATTAGAATTCACACTGGCGAGAGACCTTTTAATTGTAAAATATGTACGAAATCTTTCACACAATCCTGTTATTTAAAATCTCATATTAGAACTCACACTGGAGAAAAACCTTTTAAATGTAAATTATGTACGAAATCTTTCACACAATCCAATAGTTTAAAATCTCATATTAGAACTCACACTAACTAA
Protein Sequence: MNISAIKEEKIEIIDESKPEFDYFDQMEKIEEHEFEIKKDLQDFKIKFQDCDEELNSERDSTKQEPNYKNISDKSFKCKICSKCFTKSCNLKSHIRTHTNEKPFKCKLCSKCFTQSGNLKNHIKIHTNEKPFKCKFCLKCFTKSEHLKRHIRTHTGEKPFKCNSCSKCFTESCNLKNHIKTHINEKSFKCEICSKCFTESGNLKKHIRTHTNEKPFKCENCSKCFTLFDNLKRHIRIHTGERPFNCKICTKSFTQSCYLKSHIRTHTGEKPFKCKLCTKSFTQSNSLKSHIRTHTN

Sequence clustering based on sequence similarity using MMseqs2