Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 4.6 3.7e+02 1.3 0.6 21 44 141 164 130 168 0.80

2 7 0.022 1.7 8.8 0.1 21 49 169 197 165 201 0.85

3 7 0.0077 0.61 10.2 0.0 20 48 224 252 214 256 0.82

4 7 0.5 39 4.4 0.1 21 44 253 276 249 281 0.90

5 7 4.7 3.7e+02 1.3 0.0 21 44 281 304 277 308 0.83

6 7 0.027 2.1 8.5 0.0 21 45 309 333 305 340 0.86

7 7 0.0035 0.28 11.3 0.1 21 44 337 360 333 363 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	4.6	3.7e+02	1.3	0.6	21	44	141	164	130	168	0.80
2	7	0.022	1.7	8.8	0.1	21	49	169	197	165	201	0.85
3	7	0.0077	0.61	10.2	0.0	20	48	224	252	214	256	0.82
4	7	0.5	39	4.4	0.1	21	44	253	276	249	281	0.90
5	7	4.7	3.7e+02	1.3	0.0	21	44	281	304	277	308	0.83
6	7	0.027	2.1	8.5	0.0	21	45	309	333	305	340	0.86
7	7	0.0035	0.28	11.3	0.1	21	44	337	360	333	363	0.91

Coding Sequence: ATGGATATTTTTGCAATAAAAGAAGAAAAAATCGAAATTATTGACGAATCAAAACCAGAATTCGACTATTTTGATCAGATGGAAAAAATTGAAGAACAGGTGAATCTTGAATCTGAAATTAAAAAAGAAGAATTACACTCTACAATAGATTTACCGGATTTTAAAATCGAATTTCAAGATTGTGATGAAGAATTAAATTCAGAGCGAGATTCAACAAAACAGGAACCGAGTTATAAAATTATTGCCGATAAATCTTTTAAATTTGAAGAACATGAGGTGAATCTTGAATTTGAAATTAAAAAAGAAGAATTACAATCTACAATAGATTTACCGGATTTTAAAATCGAATCTCAAGATTCTGATGAAGAATTAAATTCAGAGCGAGATTCAACAAAACATGAACCGAATTATAAAAATATTGCCGATAAATCTTTTAAATGTAAAATTTGTTCGAAATGTTTCACACAATTGTGTCATTTAAGAGCTCATATTAGAACTCACACTGGAGAAAGACCTTTTAAATGTCAATTATGTTCGAAATCTTTCACACAATCCGGTAATTTAAAAAGTCATATTAAAACTCACACAAACGAGAAACCTTTTAAATGTGAAAATTGTTCGAAATGTTTCACACTTTTTGATACTTTAAAAAAGCATATTAGAACTCACACTAACGAGAAACCTTTTAAATGTAAATTATGTTCGAAATCTTTCACACAATCCGGTAATTTAAAAAATCATATGAAAACTCACACTAACGAAAAACCTTTTAAATGTAAATTATGTTCGAAATGTTTCGCACAATCCGGTAGTTTAAAATGTCATATTAGAACTCACACTAACGAAAATCCTTTTAAATGTGAAATATGTTCAAAAGGTTTCACATATTCTGATAGTCTAAAAATTCATATTAGAACTCACACTAACGAGAAACCTTTTAAATGTGAAATATGTTCAAAAGATTTTACACATTCCAGTAATTTAAAAAAACACATTAGAACTCACATTAACGAAAAACCATTTAAATGTGAAATTTGTTCGAAATATTTTAAACAATCGCGTAGTTTAAAAATTCATATAAAAAATCACTAA
Protein Sequence: MDIFAIKEEKIEIIDESKPEFDYFDQMEKIEEQVNLESEIKKEELHSTIDLPDFKIEFQDCDEELNSERDSTKQEPSYKIIADKSFKFEEHEVNLEFEIKKEELQSTIDLPDFKIESQDSDEELNSERDSTKHEPNYKNIADKSFKCKICSKCFTQLCHLRAHIRTHTGERPFKCQLCSKSFTQSGNLKSHIKTHTNEKPFKCENCSKCFTLFDTLKKHIRTHTNEKPFKCKLCSKSFTQSGNLKNHMKTHTNEKPFKCKLCSKCFAQSGSLKCHIRTHTNENPFKCEICSKGFTYSDSLKIHIRTHTNEKPFKCEICSKDFTHSSNLKKHIRTHINEKPFKCEICSKYFKQSRSLKIHIKNH

Sequence clustering based on sequence similarity using MMseqs2