Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0011 0.084 13.0 0.2 21 44 17 40 9 44 0.88

2 9 0.0026 0.21 11.7 0.1 21 44 45 68 41 76 0.90

3 9 2.2 1.8e+02 2.3 0.3 22 44 74 96 68 100 0.86

4 9 0.003 0.24 11.5 0.1 21 44 101 124 97 128 0.90

5 9 4.6 3.7e+02 1.3 0.1 22 43 130 151 125 156 0.82

6 9 0.017 1.4 9.1 0.0 21 51 157 187 147 189 0.85

7 9 3.3 2.6e+02 1.8 0.2 23 44 187 208 183 212 0.88

8 9 8.1e-05 0.0064 16.6 0.7 16 51 209 244 205 247 0.87

9 9 0.27 22 5.3 0.0 21 46 270 295 264 302 0.83

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0011	0.084	13.0	0.2	21	44	17	40	9	44	0.88
2	9	0.0026	0.21	11.7	0.1	21	44	45	68	41	76	0.90
3	9	2.2	1.8e+02	2.3	0.3	22	44	74	96	68	100	0.86
4	9	0.003	0.24	11.5	0.1	21	44	101	124	97	128	0.90
5	9	4.6	3.7e+02	1.3	0.1	22	43	130	151	125	156	0.82
6	9	0.017	1.4	9.1	0.0	21	51	157	187	147	189	0.85
7	9	3.3	2.6e+02	1.8	0.2	23	44	187	208	183	212	0.88
8	9	8.1e-05	0.0064	16.6	0.7	16	51	209	244	205	247	0.87
9	9	0.27	22	5.3	0.0	21	46	270	295	264	302	0.83

Coding Sequence: ATGTTTCAAACATTCCAGTACCTTAAAACTCATATTAGAACTCACACTGACGAGAAACCTATTAAATGTAACATATGTTCGAAATGTTTCAGAGATTCCAGTAACTTAAAAAGTCATATTAGAACTCATACTGACGAGAAACCTTTTAAATGTAAAATATGTTCGAAATGTTTCACACAATCCAATAATTTAAAAAGTCATGTTAGAACTCACACTGGCGAGAAATCTTTTAAATGTAAAATTTGTTCAAAATGTTTCACACATTCCAGTACCTTAAGAATTCATATTAGAACTCATACTGACGAGAAACCTTTCAAATGTAAAATTTGTTCGAAATGTTTCACACAATCCAATAATTTAAAAAGTCATGTTAGAACTCACACTGGCGAGAAATCTTTTAAATGTAAAATTTGTTCAAAATGTTTCACACAATCCAGTACCTTAAAAACTTATATTAGAACTCACAATGACGAGAAACCTTTTAAATGTAAAATATGTTCGAAATGTTTCACACAATTGGGTAATTTAAAAACTCATATTAGAATTCACACTGACAAGAAACCTTTTAAATGTGAAATATGTTCGAAATGCTTCAACCATTCTATTAGTTTAAAAACTCATATTAGATCTCACACTGGCGAGAAACAACCTTTTAGATGTAAAATTTGTTCAAAATGTTTCACAAAATCCAGTAATTTAAAAAGACATATTAGAATTCACAGTGACGAGAAACCTTTTAAATGTAAGTTTTGTTCAAAATGTTTCACAGATTCCAGTAGTTTAATATTTCATAATAGAACTCACACTGATGAGAAACCTTTTAAACGTAAAATTTGTTCGAAATGTTTCACACAATCCAGTAATTTAAAAGGTCATGTTAGAACTCACACTGACGAGAAACCTTTTAAATGTTTTCGAAATGTTTCACACAATCCGGTGAATTAA
Protein Sequence: MFQTFQYLKTHIRTHTDEKPIKCNICSKCFRDSSNLKSHIRTHTDEKPFKCKICSKCFTQSNNLKSHVRTHTGEKSFKCKICSKCFTHSSTLRIHIRTHTDEKPFKCKICSKCFTQSNNLKSHVRTHTGEKSFKCKICSKCFTQSSTLKTYIRTHNDEKPFKCKICSKCFTQLGNLKTHIRIHTDKKPFKCEICSKCFNHSISLKTHIRSHTGEKQPFRCKICSKCFTKSSNLKRHIRIHSDEKPFKCKFCSKCFTDSSSLIFHNRTHTDEKPFKRKICSKCFTQSSNLKGHVRTHTDEKPFKCFRNVSHNPVN

Sequence clustering based on sequence similarity using MMseqs2