Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.025 2 8.6 0.0 25 46 87 108 78 115 0.83

2 10 1.7 1.4e+02 2.7 0.0 21 47 111 137 106 143 0.81

3 10 0.11 8.6 6.6 0.1 21 44 139 162 131 166 0.87

4 10 0.047 3.7 7.7 0.1 21 45 167 191 163 199 0.87

5 10 0.15 12 6.1 0.0 21 45 195 219 191 226 0.87

6 10 0.17 13 5.9 0.0 21 46 223 248 219 254 0.86

7 10 1.8 1.4e+02 2.7 0.1 21 44 251 274 247 278 0.87

8 10 0.02 1.6 8.9 0.0 21 46 279 304 274 310 0.87

9 10 0.2 16 5.7 0.0 21 47 307 333 304 338 0.85

10 10 0.092 7.3 6.8 0.0 21 45 335 359 331 361 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.025	2	8.6	0.0	25	46	87	108	78	115	0.83
2	10	1.7	1.4e+02	2.7	0.0	21	47	111	137	106	143	0.81
3	10	0.11	8.6	6.6	0.1	21	44	139	162	131	166	0.87
4	10	0.047	3.7	7.7	0.1	21	45	167	191	163	199	0.87
5	10	0.15	12	6.1	0.0	21	45	195	219	191	226	0.87
6	10	0.17	13	5.9	0.0	21	46	223	248	219	254	0.86
7	10	1.8	1.4e+02	2.7	0.1	21	44	251	274	247	278	0.87
8	10	0.02	1.6	8.9	0.0	21	46	279	304	274	310	0.87
9	10	0.2	16	5.7	0.0	21	47	307	333	304	338	0.85
10	10	0.092	7.3	6.8	0.0	21	45	335	359	331	361	0.90

Coding Sequence: ATGAATATTTGTGCAATAAAAGAAGAAAAAATCGAAATTATTGACGAATCACAACCAGAAATCGACAATTTTGATCAGATGGAAAAAAGTGAAGAACATGAGGTGAATGTTGAATTTGAAATTAAAAAAGAAGAATTACACTCTACAATAGATTTACCGGATTTTAAAATCGAATCTCAAGATTTTGATGAAGAATTAAATTCAGAGCGAGATTCAATAAAACATAACTCGAGTTATAAAAATATTGCCGATAAATCTTTTAAATGTAAGATTTGTTCGAAATGTTTCACACAATCCGGTAATTTAAAAAAGCACATTAGAAGTCACACTAATGAGAAACCTTTTAAATGTGAAAATTGTTCAAAATGTTTCAAACTTTTGGATAATTTAAAAAAGCATATTAGAACTCACACTAACGAGAAACCTTTTAAATGTAAAATATGTTCGAAATCTTTCACACAATCGAGTTATTTAAAATGTCATATTAGAACTCACACTGGAGAAAAACCTTTTAAATGTAATATTTGTTCGAAATATTTCACACAATCCTGTCATTTAAAAAATCATATTAAAACTTACACTGGAGAAAAACCTTTTAAATGTAAATTATGTTCGAAATGTTTCACACAATCGGATAAATTAAAAAATCATATTAGAACTCACACAGGCGAGAAACCTTTTAAATGTAATATTTGTTCGAAATATTTCTCAGACTCCAGTACTTTAAAAAAGCATATTAGAACTCACACTGGAGAAAAACCATTTAAATGTGAAATTTGTTCGAAATGTTTCACAACATCCGGTTATTTAAAATGTCATATTAAAACTCACACTGGAGAAAAACCTTTTAAATGTAAATTATGTTCGAAATCTTTCACACAATCCGGTAATTTAAAAAATCATATTAAAACTCACACTGGAGAAAAACCATTTAAATGTGAAATTTGTTCGAAATATTTCTCAGACTCCAGTACTTTAAAAAAGCATATTAGAACTCACACGAACGAAAAACCATTTAAATGTGAAATTTCTTCGAAATATTTTAAACAATCCCGTTGTTTAAAAAATCATATAAAAACTCACTAA
Protein Sequence: MNICAIKEEKIEIIDESQPEIDNFDQMEKSEEHEVNVEFEIKKEELHSTIDLPDFKIESQDFDEELNSERDSIKHNSSYKNIADKSFKCKICSKCFTQSGNLKKHIRSHTNEKPFKCENCSKCFKLLDNLKKHIRTHTNEKPFKCKICSKSFTQSSYLKCHIRTHTGEKPFKCNICSKYFTQSCHLKNHIKTYTGEKPFKCKLCSKCFTQSDKLKNHIRTHTGEKPFKCNICSKYFSDSSTLKKHIRTHTGEKPFKCEICSKCFTTSGYLKCHIKTHTGEKPFKCKLCSKSFTQSGNLKNHIKTHTGEKPFKCEICSKYFSDSSTLKKHIRTHTNEKPFKCEISSKYFKQSRCLKNHIKTH

Sequence clustering based on sequence similarity using MMseqs2