Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.11 8.6 6.6 0.1 26 44 8 26 2 30 0.86

2 9 0.025 2 8.6 0.0 21 46 31 56 27 62 0.86

3 9 0.024 1.9 8.6 0.1 21 44 59 82 55 86 0.91

4 9 0.028 2.2 8.4 0.2 18 45 83 111 79 114 0.82

5 9 0.0071 0.56 10.4 0.1 21 44 115 138 113 143 0.91

6 9 0.025 2 8.6 0.1 21 45 143 167 139 170 0.90

7 9 0.024 1.9 8.6 0.1 21 44 171 194 167 198 0.91

8 9 0.015 1.2 9.3 0.2 21 46 199 224 195 230 0.85

9 9 1.1 86 3.4 0.1 22 44 228 250 223 253 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.11	8.6	6.6	0.1	26	44	8	26	2	30	0.86
2	9	0.025	2	8.6	0.0	21	46	31	56	27	62	0.86
3	9	0.024	1.9	8.6	0.1	21	44	59	82	55	86	0.91
4	9	0.028	2.2	8.4	0.2	18	45	83	111	79	114	0.82
5	9	0.0071	0.56	10.4	0.1	21	44	115	138	113	143	0.91
6	9	0.025	2	8.6	0.1	21	45	143	167	139	170	0.90
7	9	0.024	1.9	8.6	0.1	21	44	171	194	167	198	0.91
8	9	0.015	1.2	9.3	0.2	21	46	199	224	195	230	0.85
9	9	1.1	86	3.4	0.1	22	44	228	250	223	253	0.87

Coding Sequence: CACACTGACGAGAAATTTTTTAAATGTAAAATTTGTTCGAAATGTTTCACACAGTCTAGTAATTTAAAAATTCATATTAGAACTCACACTGATGAGAAACCTTTTAAATGTAAAATTTGTTCGAAATGTTTTACACAATCTGGTCATTTAAAAACTCACATTAAAACTCACACTGACGAGAAACCTTTTAAATGTAAAATATGTTTAAAGTGTTTCACACAATCCAGTAGTTTAAAAACTCATATTAGATCTCACACTGACGACCAACCTTTTAAATGTAAAATATGTTTAAAATGTTTCACACATTCCAATCACTTAAAAACTCATATTAGAATTCACACTGACGAAAAACCTTTTAAATGTAAAATTTGTTCGAAATGTTTCACACAATCCAGTAATTTAAATACTCATATCAGAACTCATACGAACGAGAAACCTTTTAAATGTAAAATTTGTTCGAAATGTTTCACACAATCCAGTCATTTAAAAACTCATATCAAAACTCACACTGACGAGAAACCTTTTAAATGTAAAATATGTTCGAAATGTTTCACACGTTCCAGTAACTTAAAAACTCATATTAGAACTCACACTGACGAAAAACCTTTTAAATGTGAAATTTGTTTAAAATGTTTCACACAATCCAGTCATTTAAAAACTCATATTAGAACTCACACTGGCCAGAAACCTTTTAAATGTAAAATTTGTTCGAAATGTTTCACAAATTCCAGTCATTTAAAAACTCATATTAAAACTCACCCTAACGAAAGCCTTTTAAATGAAAAATTTGTTCGAAATGTTTCACACTGA
Protein Sequence: HTDEKFFKCKICSKCFTQSSNLKIHIRTHTDEKPFKCKICSKCFTQSGHLKTHIKTHTDEKPFKCKICLKCFTQSSSLKTHIRSHTDDQPFKCKICLKCFTHSNHLKTHIRIHTDEKPFKCKICSKCFTQSSNLNTHIRTHTNEKPFKCKICSKCFTQSSHLKTHIKTHTDEKPFKCKICSKCFTRSSNLKTHIRTHTDEKPFKCEICLKCFTQSSHLKTHIRTHTGQKPFKCKICSKCFTNSSHLKTHIKTHPNESLLNEKFVRNVSH

Sequence clustering based on sequence similarity using MMseqs2