Basic Information

Transcription Factor Domain

TF Family: SAND
Domain: SAND domain
PFAM: PF01342
TF Group: Other Alpha-Helix Group
Description: The DNA binding activity of two proteins has been mapped to the SAND domain. The conserved KDWK motif is necessary for DNA binding, and it appears to be important for dimerisation [1]. This region is also found in the putative transcription factor RegA from the multicellular green alga Volvox cateri. This region of RegA is known as the VARL domain [2].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.019 4.4e+02 3.3 0.0 27 42 26 41 4 45 0.78

2 10 0.021 4.9e+02 3.1 0.0 28 43 56 71 52 81 0.84

3 10 0.027 6.4e+02 2.8 0.0 28 42 82 96 76 102 0.87

4 10 0.029 6.9e+02 2.6 0.0 28 42 111 125 105 129 0.87

5 10 0.03 7.2e+02 2.6 0.0 28 42 137 151 132 155 0.87

6 10 0.022 5.3e+02 3.0 0.0 28 42 166 180 161 186 0.86

7 10 0.03 7.1e+02 2.6 0.0 28 42 192 206 187 212 0.87

8 10 0.024 5.7e+02 2.9 0.0 28 43 221 236 215 244 0.87

9 10 0.022 5.2e+02 3.0 0.0 28 43 247 262 243 271 0.85

10 10 0.022 5.2e+02 3.0 0.0 28 43 273 288 268 302 0.85

#	of	c-Evalue	i-Evalue	score	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.019	4.4e+02	3.3	27	42	26	41	4	45	0.78
2	10	0.021	4.9e+02	3.1	28	43	56	71	52	81	0.84
3	10	0.027	6.4e+02	2.8	28	42	82	96	76	102	0.87
4	10	0.029	6.9e+02	2.6	28	42	111	125	105	129	0.87
5	10	0.03	7.2e+02	2.6	28	42	137	151	132	155	0.87
6	10	0.022	5.3e+02	3.0	28	42	166	180	161	186	0.86
7	10	0.03	7.1e+02	2.6	28	42	192	206	187	212	0.87
8	10	0.024	5.7e+02	2.9	28	43	221	236	215	244	0.87
9	10	0.022	5.2e+02	3.0	28	43	247	262	243	271	0.85
10	10	0.022	5.2e+02	3.0	28	43	273	288	268	302	0.85

Coding Sequence: ATGGAAAGAGCATTGACCTGTCCAAACGCTGGCTGTCTCCTGCTACAAAAGAACCCCCCGTCACGGACTGCCAACCACTATGGAAAGAGCATTGACCTTTCCAAACGCTGGCTGTCTCCTGCTAGAATAGAACCCCCCAACCCACCGTCACGGACTGCCAACCACTATGGAAAGAGCATTGACCTGTCTAAACGCTGGCTGTCTCCTGCTAGATTAGAACCCCCGTCACGGACTGCCAACCACTATGGAAAGAGCATTGACCTGTCCAAACGCTGGCTGTCTCCTGCTAGAATAGAACCCACCAACCCACCGTCACGGACTGCCAACCACTATGGAAAGAGCATTGACCTGTCCAAACGCTGGCTGTCTCCTGCTAGAATAGAACCCCCGTCATGGACTGCCAACCACTATGGAAAGAGCATTGACCTGTCCAAACGCTGGCTGTCTCCTGCTAGAATAGAACCCCCCAACCCACCGTCACGGACTTCCAACCACTATGGAAAGAGCATTGACCTGTCTAAACGCTGGCTGTCTCCTGCTAGATTAGAACCCCCGTCATGGACTGCCAACCACTATGGAAAGAGCATTGACCTGTCCAAACGCTGGATATCTCCTGCTAGAATAGAACCCACCAACCCACCGTCACGGACTGCCAACCACTATGGAAAGAGCATTGACCTGTCCAAACGCTGGCTGTCTCCTGCTAGATTAGAACCCCCGTCATGGACTGCCAACCACTATGGAAAGAGCATTGACCTGTCTAAACGCTGGCTGTCTCCTGCTAGATTAGAACCCCCATCACGGACTGCCAACCACTATGGAAAGAGCATTGACCTGTCCAAACGCTGGCTGTCTCCTGCTAGAATAGAACCCACCGTCACGGACTGCCAACCACTATGGAAAGAGCATTGA
Protein Sequence: MERALTCPNAGCLLLQKNPPSRTANHYGKSIDLSKRWLSPARIEPPNPPSRTANHYGKSIDLSKRWLSPARLEPPSRTANHYGKSIDLSKRWLSPARIEPTNPPSRTANHYGKSIDLSKRWLSPARIEPPSWTANHYGKSIDLSKRWLSPARIEPPNPPSRTSNHYGKSIDLSKRWLSPARLEPPSWTANHYGKSIDLSKRWISPARIEPTNPPSRTANHYGKSIDLSKRWLSPARLEPPSWTANHYGKSIDLSKRWLSPARLEPPSRTANHYGKSIDLSKRWLSPARIEPTVTDCQPLWKEH

Sequence clustering based on sequence similarity using MMseqs2