Acur003148.1
Basic Information
- Insect
- Aleochara curtula
- Gene Symbol
- topi
- Assembly
- GCA_963978815.1
- Location
- OZ022216.1:9254364-9256995[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.00034 0.034 14.4 2.4 2 21 153 172 152 173 0.94 2 13 1.1e-07 1.1e-05 25.4 0.6 1 23 198 220 198 220 0.97 3 13 0.035 3.5 8.1 0.8 3 23 228 248 227 248 0.95 4 13 2.4 2.5e+02 2.3 0.1 2 13 267 278 266 286 0.79 5 13 0.0079 0.8 10.1 1.1 2 23 354 375 353 375 0.94 6 13 0.94 95 3.6 6.0 2 22 418 438 417 441 0.86 7 13 0.34 34 5.0 0.1 1 23 578 601 578 601 0.96 8 13 0.00099 0.1 13.0 0.3 1 23 605 627 605 627 0.97 9 13 6.8e-06 0.00068 19.8 5.4 1 23 633 655 633 655 0.98 10 13 0.014 1.4 9.4 0.2 1 23 661 686 661 686 0.96 11 13 0.068 6.8 7.2 2.9 1 23 692 714 692 714 0.86 12 13 1.6e-06 0.00016 21.8 1.5 1 23 720 742 720 742 0.98 13 13 2.4e-06 0.00024 21.2 0.9 1 23 748 771 748 771 0.98
Sequence Information
- Coding Sequence
- ATGAATCGCAACGAAAACATTTCATATTTGAAAATACACAAATTGTTTCCGGACTCTTCGATCAAATCGATGAAACTTAAATTTGAGTCCCGCTCTCATCGTATTCTGGGCAAAACTCCCATATACGTGGATGTGGAGCCAATTTATGACAGATTCATGAAGGAAACCCATCCcgggaaatttaatttcggaCTGAGTTTTAACTTGAGTGGGTCGGCGGTTCGGGTAATTAGATTAGGCAAAGTCGAAGACCTCAACCCTGCTAACTATCCAACAGAAATTCGAACAATGCATAATGATCTCAATGACATACCTAATGCAGTTACGGTCTCACAAACCACAACTGATAATAAGCACAATAAAAGCTGCAAACCTTTACCGGAAGGTATGGAAAAAATAAAGAATCTGACTAGTGCTAAGCGTGAGTCAAAGGTTCCCAATATTCCAATGATGATTCGTTGTCAAAATTGCGATACAAATTTCCCGACCAAGTATCAATTTCAGCGGCACCAATGCGAATTTAATGCCGAGAAGGTGGTGTTAAAGCCAAATATCGACGTTCGCGACGTGGATAAAGGTATGCGAATGAAATATGATTGTGGTACATGTGGAAAGCAATTTGTTAGCAAAAGTAATCTGGAGCGTCATCTCAATAGTCATAATAATGGCAATGCTAACATTTGCGAATTCTGCAGTAAACAGTTTGTTAGTGAAAATCGGCTGCGCATTCATAAAGAGAACCATTGCAAAAAGGCCGGAGACATAAGCAAATTCTACCGAAGTGATGTCACCGTTTGGAGGTGCGCAAAATGTTATCAAGTCTTTTCATCTGACGAATTTGCTATTACTCACGTTACTGAATGTACTGATATTGTGTCGGAtccaattgcaattaaaaacgcAAACGAAAATGTCTCATCGGTGTTAGCGCTTAAGGACGGAATAATCACGTCAATGGATACGGAACTCCCTGAAGATGAGTTAGTAAATGCAATGAATTATGGAACCAACAAAAGTTGCTGCACGCTGGTCGAGAAGGTTCGGACCGAATTGTTATTGCAGTGCGAATTCTGCAACCGAACGTACGCCAATAAAAAATCGTTGGTGTTTCATCAGGATATGCACAatactgaaattaattataattgtataATGTGCAATGCGACCTTTGAATCGTACGCAGTTGCAGCAAAACATTGGCTCACAGAATGTGCAAATGAAGCAAATCTTTTCTATCTGCCAAAgttgatttattgcaaatgctgTGATCGTACATTCAAATCGCACGAATTACTTTATATGcacaaaatgaagaagaagcactACACACCAAAAAGGCATCGAACTTTAAATATCGACGCCCAGCTTCCGTCAGAATCACAACTACCCGTTGACGGATTAAACAAAGACACCTTGATAACTCAGGACTGTGACGCGAATAAGGATACTATGATTAAATTGATTGAAGGGGTGCTATGTTCAATTAATCATAATcttaatgatgatgaaacacAGCTAAGCATATTGGGCTCTGAATCAAACTCTACACCAGCCGAAATGTCTGGCAAGCAGGATGCGCTTGCATCTGAAGTTTCCAAGGGTTTGCTGAATGTTGCGGACGTAGAACTCACCGAAGAAAACACTGGCAAGAAGCGACGTGGTCGAAAACGCAAACATCCAATTCAATCTAAAACGAAACGACCATGCCCTGGTGTTACACCAGGATATAAGTTTCAATGTGAGCGTTGCATCAATGTCTTTGATTCTGTAATTGATCTCGAAGTACATCGCAACAAGGATCACCCAGCAAATTACAAATGTGAAGAGTGTGATCAAGTCGTACATAGCTCCAAGGCTTTGATAATTCATAGCAGAGCGCATCAAAGCCTCAAGCCATATGTATGTGAAATTTGTAAAAGATGCTATTCACAAACTTCTCATTTATGGCAACATATGAGGTTTCATCAaggtattaaACCTTTTGCATGTCCACATGAAGGATGCGAAGCAAGATATACAATTCGTCCAGATCTCAAAGATCACATTCGTAAGGTTCACACTCGTGAACGACCCTTCAAGTGTTCCGTTTGTGACAAATGTTTTTTGACTGGTTCAGTTTATTATCAGCATAGATTAATCCATACCAATGATCGGAGATACGCATGTGATATTTGCCATAAAAGATTCTTCCGTGCAGATGCATTGAATAATCATCGTCGTATTCATACTGATGAACGACCTTATCCTTGCAATGTATGCGGTCGCAATTTTAGACAAAAAGGCGATCGCAATAAGCATGTGAGAACTCAGCATCCTGCATATGCATGA
- Protein Sequence
- MNRNENISYLKIHKLFPDSSIKSMKLKFESRSHRILGKTPIYVDVEPIYDRFMKETHPGKFNFGLSFNLSGSAVRVIRLGKVEDLNPANYPTEIRTMHNDLNDIPNAVTVSQTTTDNKHNKSCKPLPEGMEKIKNLTSAKRESKVPNIPMMIRCQNCDTNFPTKYQFQRHQCEFNAEKVVLKPNIDVRDVDKGMRMKYDCGTCGKQFVSKSNLERHLNSHNNGNANICEFCSKQFVSENRLRIHKENHCKKAGDISKFYRSDVTVWRCAKCYQVFSSDEFAITHVTECTDIVSDPIAIKNANENVSSVLALKDGIITSMDTELPEDELVNAMNYGTNKSCCTLVEKVRTELLLQCEFCNRTYANKKSLVFHQDMHNTEINYNCIMCNATFESYAVAAKHWLTECANEANLFYLPKLIYCKCCDRTFKSHELLYMHKMKKKHYTPKRHRTLNIDAQLPSESQLPVDGLNKDTLITQDCDANKDTMIKLIEGVLCSINHNLNDDETQLSILGSESNSTPAEMSGKQDALASEVSKGLLNVADVELTEENTGKKRRGRKRKHPIQSKTKRPCPGVTPGYKFQCERCINVFDSVIDLEVHRNKDHPANYKCEECDQVVHSSKALIIHSRAHQSLKPYVCEICKRCYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCSVCDKCFLTGSVYYQHRLIHTNDRRYACDICHKRFFRADALNNHRRIHTDERPYPCNVCGRNFRQKGDRNKHVRTQHPAYA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00084080;
- 90% Identity
- -
- 80% Identity
- -