Basic Information

Gene Symbol
-
Assembly
GCA_963978815.1
Location
OZ022221.1:10740625-10743540[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 5.4 5.4e+02 1.2 0.0 3 23 9 29 8 29 0.91
2 14 0.3 30 5.2 2.1 1 23 469 492 469 492 0.89
3 14 0.0072 0.72 10.3 0.1 1 23 620 642 620 642 0.98
4 14 7.2e-06 0.00072 19.7 3.6 2 23 645 666 644 666 0.97
5 14 0.0042 0.42 11.0 2.6 1 23 672 694 672 694 0.98
6 14 9.8e-06 0.00098 19.3 2.5 2 23 701 723 700 723 0.96
7 14 0.031 3.1 8.3 1.2 1 23 733 755 733 755 0.97
8 14 7e-06 0.0007 19.8 0.9 3 23 762 783 761 783 0.97
9 14 0.12 12 6.4 0.1 2 23 799 819 798 819 0.95
10 14 0.00023 0.023 15.0 1.8 1 20 825 844 825 847 0.92
11 14 3.3e-05 0.0033 17.6 0.3 1 23 855 877 855 877 0.99
12 14 0.00066 0.067 13.5 3.8 1 23 883 905 883 905 0.97
13 14 1.1e-06 0.00011 22.3 4.8 1 23 911 933 911 933 0.97
14 14 0.00028 0.028 14.7 5.7 1 23 939 961 939 962 0.96

Sequence Information

Coding Sequence
ATGGCCCTGGAGAGCTCGGTTATTTGCCCAGTATGCACCCTCTTCTTGAGGCCTGGGATGTCACTGGCTGCTCATTTAGAATTACACTCAAAAGATAAACTCATTGAAGTTATGGTAAAATGGAATTCCAAACCAGAGACAGTGATTGATGATATTCCTCCCTTGGTGCCAGTTACTACTAAAGCACCAACTCAAATGCTTCCGCAACCATGGATTGCAGATGCACCAACAGGTTATATGCCATCAGTGTTTACTCCAGGGGCACCTATGCAAGTTGGACAATCTCTGCCTGCTCTAGGGCAACCTGTGCTAACAATGCCCCATCAACTATCACAAACAGTAACTGGAAGCAATGCATCCAGTCAAGGTAATCATTCATTCTTCTATCAGCAGATTATGAGCTCATCGACTCCATCAACACCAACCAGTTATATACATCATAATGGTGTACCAATTCCAATTTACAATCAGCCAGCATTTCCACAATTTGTATACCAACAACAGCAAATGTTCATGTCATCTGGCCCTCCACCTTTGGTTCCTATTGGTGGTTCTGATTCAATAACTCAAAAAGATGAGAAATCAAAtagtgaaaatttattaccacAAATTATAGAGATTCAGGAGGAACAAACAGATCAGGagaatgttgatgatgatatgGAGACCTTAAAGTCAAGTGCAAAAGTGTCTACCAAAGAGCAGGAAAATCAAGCAATTGCTGATGACATTAAATCGCCAAGTCCTGCTACAATTGCTGAAGATATAGATAAGCCATATGAAACAATAACTGATGTTTATTTTGAGACAGATGTTCAACTGGAGGGAATAAAAGGTGATGAGAAATTAGATATTGAAATTGGTCCagaaatgataaatttagGGAGAGGCAGAACGCCGGACGTTGCTGAAGCCTATACTCTCAATCAAGGAGTTAATCATAATCACTTTGATGTTAGTGATGTGAATTTGGATTTAGGACAAGAGTTTATCGAGTCCCAAAACGCCATACCATCCACTACTGAAGACCATGATTATTCAGGCGGTACATTTAAATCTGAACGTCCATCTATATTGATGAGCATAAATGATTATGAAAATCGTGACGAGAATATTTCGACTGATAGTGTAAATATACGCTCTGATGAAAATATGCCTCCAAGAGGTGAATTATCAGGGCAAGAAAGCAATGCTAGTGACGTTGCTTCATGGTCTCGCCTACAATACCAAGAAGGTTCATCGCGAATGTCCACTGCCATGTCAACTTATGATTTACTTGCAAGGGAGAGCTGGGAGGGTTCAGATGTATCCGAAACAGATGAGCCGCCTCCGTACCAGAGCCGTTCTCCAACGTGCATTACTGCTGGTGATGACGATGCCAGCACTAGTAGGCCGAGGATTAGCTACAAATGTAATTCATGCGATATGTCCTTTCCGTGCCCAAAGGAACGTCGCGTGCATCAATCGGAGACCCATGGTGCAAGCAACATGTCTACGACTGATCGTCTGGTTGTATGCAACGAAGATGTAAAGCCGGTTCCAAATGATTCTACAAGCACGGCTGGGTTACCAGTATTTGGGCAAACTGTTAATAAACTGATTGTTAAATCCAAGAGTGAAGAGGAAGTTAAGACTGATTCGATCGAAAGTTCATTCGATCacatttttaataacattattaattttaatgaagaaGATGCCGCAGCGAAGAAACCTACAGTCACCGGGGCGGAGTTGGCCGTGTGCGATGAGAGGTTTGCAAATACGATCATCTGCGTGATTTGCTGTTCTGTGGTAAATGAATGTACGCTGAAAGAGCACCAAATGAACATCCACGGGTTCAGCTTTGAGACAAAGTATAAATGTGGAGTTTGTTTAGAGGAGTTTACGACCGAGCCCCCATACACGAAGCATTTGAGTGTCCATCCTTTGGAATGCCAGCACTGCGGCAAACACTTTTTCCGCTGGAATAATCTCGCACTCCACATCAAGCGGCACCTCGGTATCAAACCCCATAAATGTACAATGTGTGCTAAATCATTTCTCACTAGGCAGAAGTTGGTTGAGCATATCAACACCCATACGGGGGAGGCACCACTCAAATGCAATATGTGCTCAGAAACGTTCAAGCGGTATTCAAATCTCATTCAACATCGGAATCGACGGCATTTGATGGTGAAGAAGCGGCTCAAAGATTTCATTTGCCCTACTTGTGGGGATTTATTCCATTCCAAGAAGAAACTCGCTTGGCACAAGGAAACGCATGAGAACAAGCCGAAGGCATGCCCGTATTGCAACGAGAAATTTGTGCATACAGTGAGCCTGACACGGCACATTAGAAGAGCACATAACGACAGATTTGTCGCAGATGCAGAACGGGCTAATGAGAATGTTGAATGCCCTATATGCAAAGGCGTTTATATGCGTAGTTCACTCGATACCCATATTAAGAACCATGGGCGAACGAAGCAATATAGCTGTACGCTGTGCTCCAAAGACTTCAGCACCAAGTGGAATTTAAAGTTGCACAAGTGGACCCACACCGGCCGAGCTCAAAAGCCCTTTCAGTGCGAGCTATGCAATAGCGGTTTCGTCCGCGAATCCGACTATACCGCGCACATGAACTCTCACAAGTCTGTGCGACCTTTTACGTGCAATTACTGTGGTGCTCAGTTTATTCGCAAATACAATTGTCAGAGACACGTGAAGGAGCACGAGCGTGTCAAGACTCATTCATGTAATGTGTGCGGGAAGACATTCCACAGGTCGTATTACCTGAATGATCATATGCGCGTTCACAATGGTGCGCGGCCCTTCGTTTGTCATATTTGTGGAAAAACAAGTGCGACGAAGAGCAATCATAATAAACATGTACGAATACATCATGCACGAGAGCCTGTAACAACAGAGAATTGA
Protein Sequence
MALESSVICPVCTLFLRPGMSLAAHLELHSKDKLIEVMVKWNSKPETVIDDIPPLVPVTTKAPTQMLPQPWIADAPTGYMPSVFTPGAPMQVGQSLPALGQPVLTMPHQLSQTVTGSNASSQGNHSFFYQQIMSSSTPSTPTSYIHHNGVPIPIYNQPAFPQFVYQQQQMFMSSGPPPLVPIGGSDSITQKDEKSNSENLLPQIIEIQEEQTDQENVDDDMETLKSSAKVSTKEQENQAIADDIKSPSPATIAEDIDKPYETITDVYFETDVQLEGIKGDEKLDIEIGPEMINLGRGRTPDVAEAYTLNQGVNHNHFDVSDVNLDLGQEFIESQNAIPSTTEDHDYSGGTFKSERPSILMSINDYENRDENISTDSVNIRSDENMPPRGELSGQESNASDVASWSRLQYQEGSSRMSTAMSTYDLLARESWEGSDVSETDEPPPYQSRSPTCITAGDDDASTSRPRISYKCNSCDMSFPCPKERRVHQSETHGASNMSTTDRLVVCNEDVKPVPNDSTSTAGLPVFGQTVNKLIVKSKSEEEVKTDSIESSFDHIFNNIINFNEEDAAAKKPTVTGAELAVCDERFANTIICVICCSVVNECTLKEHQMNIHGFSFETKYKCGVCLEEFTTEPPYTKHLSVHPLECQHCGKHFFRWNNLALHIKRHLGIKPHKCTMCAKSFLTRQKLVEHINTHTGEAPLKCNMCSETFKRYSNLIQHRNRRHLMVKKRLKDFICPTCGDLFHSKKKLAWHKETHENKPKACPYCNEKFVHTVSLTRHIRRAHNDRFVADAERANENVECPICKGVYMRSSLDTHIKNHGRTKQYSCTLCSKDFSTKWNLKLHKWTHTGRAQKPFQCELCNSGFVRESDYTAHMNSHKSVRPFTCNYCGAQFIRKYNCQRHVKEHERVKTHSCNVCGKTFHRSYYLNDHMRVHNGARPFVCHICGKTSATKSNHNKHVRIHHAREPVTTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00084067;
90% Identity
-
80% Identity
-