Arep018352.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Alcis repandata
Gene Symbol
LZTR1
Assembly
GCA_949125135.1
Location
OX421241.1:4654296-4663033[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 8.9e-16 3.2e-13 50.5 0.0 5 108 367 495 363 497 0.84
2 3 1.8e-16 6.3e-14 52.7 0.0 6 96 586 671 581 687 0.82
3 3 5.6 2e+03 -0.4 0.0 77 100 686 709 675 718 0.76

Sequence Information

Coding Sequence
ATGGCGAGTTCCAGCCTTGGGAAAATGCTGACAGATCAGCTCCGTAATCCAAACGAGCTGGACATAAGTCTCAGAATGGAGTTTGGTCCGTTTGAGACCGTGCACAAGTGGAAACGATTATCGGAGTGCTATGAATTTGTTGGCGCCAAACGAAGTAAACACACGGTAGTGGCATATGGCACAGGGCTGTATATATTCGGCGGTGACAATGGCAAGTCTATGCTGAACGATCTGATCCGCTTTGATATAAATGAGATGTCATGGACCAGAGCGGGCTGCGTGGGCGACCCGCCTGCACCGCGCTATCATCACTCAGCAGTCATCTACCGCACCTCAATGTTCATATTCGGCGGGTACACGGGCGACATCCTCGCCAACTCCAACCTGACCAACAAGAACGACCTCTACGAGTACCGCTTCTCCAGCTGCATGTGGGTCAAATGGACTTTCAAAGGACAgGAGCCCGTGCCGCGGTCGGCGCACGGCGCGGTGGTATACGACGACAAACTGTGGATATTCGCCGGGTACGACGGAAACGCGCGTCTCAACGACATGTGGACCTGCAGCCTTATTACCGAAGTACACCAATGGGAGCGAATTGAGCAGAAAGGTCAATGCCCACCGACATGCTGCAACTTCCCTGTGTGCGTGGCGCGGGGTTGCATGTTTGTGTTCAGTGGACAGAGCGGGGCCAAGATCACCAACGCACTATTCCAGTTCCACTTTGAAACTCAAACCTGGACCCGCGTGTGCACGGAGCACCTGCTCCGCTGCGCcgggcccgcgcccgcgcgccgGTACGGACACGTCATGGTGGCGCACACGAGGCATCTGTACGTGTTCGGGGGCGCCGCCGACAACACGCTGCCGGCAGACGTGTACTGCTTCGATCTGGATACCAAGATGTGGTCGGTGGTACAGCCAGCGACAGATTCACAAGTTCCCTCGGGGCGGTTGTTCCACGCGGGCGCAGTCCTCAACGATGGCTTCTATATCTTTGGTGGAACTGTAGACAACAACGTGCGCAGTGGAGACCTGTACAGGTTCCAGTTATCAAACTACCCGCGCTGTACCCTCCAAGAAGACTTCGGCCTCATCCTGAAGTCTCAGCAGttctgtgacgtcacactgcTGGTGGGAAGCGAGGAGACGCCCGTAGCGGCGCACCAAGCGATGCTCGCCGCCAGGTCTCACTTCCTCAAGGCTAAGATCAAAGAGGCGCGAGAGCAGTTTTCACTAGAGCTAGTACCAGTTCAGACCGAAGAGTCTGCGCTGCCCAAACTGATCGTCAAACTGCCGGAGGCGACGCCTGAAGCGTTCAATATGGTGCTCAATTACATCTATACGGATAGAATCGATCCTACTGAAAAGGACGAGGACCCGGCCTCCCCGGCCACGGTGCTGCTGGTTATGGAAGTCCTGGGCCTGGCGCTGCGGCTCAGCATCCCCCGGCTGCGTGGGCTGTGCGCGCGCTACCTGCGGGCCAACATGTGTGCGGGGAACGTGCTGCCGGCGCTGCACGCCGCGCACCACTCGCGGCTCGCGTGCATCAAGGAGTACTGCCTCAGATTTGTAGTGAAAGACTACAACTTCACTCCGATAGTGATGTCTAAAGAGTTCGAGGAGATGGATCAGAGTCTGATGGTGGAAGTGATACGGCGCCGGCAGCAGCCGCCGACCAAGCAGCCCAGCGCGCAGGACTCTGACGAGGATATCGTTGGTACAACGTTAGAGCAAGACATGGCTGCCTTATTACAAAGCGGCGCGGAACTAAGTGACGTGACGCTCCGCGTGGGCGCACACCCGCGGCCCGCGCACCGCTCGGTGCTCGTCGCGCGCGCTTCTTACTTCGAGGCACTGTTCCGGTCCTTCGCGCCTAAggacaatattataaatATACCTTCAGAAGAGGCCTTCGATACCCTGCTGCGGTATATCTACCACGGAGATACGAGCATGCGCACTGAAGACTCGCTCTATCTCTTTCAAGCGCCGATTTATTACGGTTTCACAAACAACCGCCTGCAAGTGTTCTGCAAGCACAACCTGCAGAGTAACGTGACGCCGGAGAATGTGCTCGCGATACTGCAGGCGGCGGACAGAATGCTCGCCGCGGATATCAAGGAGTATGCCCTAAAGATGatcgtttataattttaaaatgGTCGCAAAACAAGACGGGCTCCGGAACCTGCCGCAGCCACTTTTAGTAGACATCCTCGACGCAATAGCAGAAGAACCGCAGTTTGACATCCACTGCCCGCAGCCAATCATCCTGCcctcgtcatcatcatcagacaCCCTCACCGAGGAAGGCGACAAGCCTGAGAAGGACAAGCATAAGTGCGGGAAGTCATAA
Protein Sequence
MASSSLGKMLTDQLRNPNELDISLRMEFGPFETVHKWKRLSECYEFVGAKRSKHTVVAYGTGLYIFGGDNGKSMLNDLIRFDINEMSWTRAGCVGDPPAPRYHHSAVIYRTSMFIFGGYTGDILANSNLTNKNDLYEYRFSSCMWVKWTFKGQEPVPRSAHGAVVYDDKLWIFAGYDGNARLNDMWTCSLITEVHQWERIEQKGQCPPTCCNFPVCVARGCMFVFSGQSGAKITNALFQFHFETQTWTRVCTEHLLRCAGPAPARRYGHVMVAHTRHLYVFGGAADNTLPADVYCFDLDTKMWSVVQPATDSQVPSGRLFHAGAVLNDGFYIFGGTVDNNVRSGDLYRFQLSNYPRCTLQEDFGLILKSQQFCDVTLLVGSEETPVAAHQAMLAARSHFLKAKIKEAREQFSLELVPVQTEESALPKLIVKLPEATPEAFNMVLNYIYTDRIDPTEKDEDPASPATVLLVMEVLGLALRLSIPRLRGLCARYLRANMCAGNVLPALHAAHHSRLACIKEYCLRFVVKDYNFTPIVMSKEFEEMDQSLMVEVIRRRQQPPTKQPSAQDSDEDIVGTTLEQDMAALLQSGAELSDVTLRVGAHPRPAHRSVLVARASYFEALFRSFAPKDNIINIPSEEAFDTLLRYIYHGDTSMRTEDSLYLFQAPIYYGFTNNRLQVFCKHNLQSNVTPENVLAILQAADRMLAADIKEYALKMIVYNFKMVAKQDGLRNLPQPLLVDILDAIAEEPQFDIHCPQPIILPSSSSSDTLTEEGDKPEKDKHKCGKS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00635518;
90% Identity
iTF_00666626; iTF_00827110; iTF_00896043; iTF_00649231; iTF_00650137; iTF_00390517; iTF_00818427; iTF_00935836; iTF_00635518; iTF_00634603; iTF_00926731; iTF_00207090; iTF_00206203; iTF_00033920; iTF_00143156; iTF_00033018;
80% Identity
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