Basic Information

Insect: Agrotis segetum
Gene Symbol: Hr39
Assembly: GCA_036375495.1
Location: JAQSVV010000070.1:123954-150295[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.16 1.9e+03 -1.1 5.4 69 192 208 335 159 364 0.57

2 3 4.4e-08 0.00052 20.5 0.1 1 21 438 458 438 468 0.91

3 3 1.1e-64 1.3e-60 206.9 0.0 151 408 490 757 467 757 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.16	1.9e+03	-1.1	5.4	69	192	208	335	159	364	0.57
2	3	4.4e-08	0.00052	20.5	0.1	1	21	438	458	438	468	0.91
3	3	1.1e-64	1.3e-60	206.9	0.0	151	408	490	757	467	757	0.84

Sequence Information

Coding Sequence: ATGAGCAGTGAGGGCGACGCGGTGAAGGTGGAGGGGGGACACGTGTCTGTCACCACTATCAGCATGTCGGGCCCGGAGACTAGCAACGGTCAGTTCTCGTACAGCTCGAGCGGCGTGCGCATCAGTGTGTCTTCAGTACCTCATGATGAAGACTCCACTGACGCCGAGATCTCCAAGATCGACTTCTCACAGCATCAATACGAGGTGAACATGCGAAACAAGAAGAAGCGCTCATTGAGTGGTGCGCAAGAGTTGGCCAGCAACGAGCGTGAACGACCCATGTCTTGGGAGGGCGAGCTGTCAGACTCCGAGATGGTTATAGACACCAGTGTTAATAATGACGAAACAAACAGTTCCCTAGACCTGCAATCCTCCAGAGACTCAATAGACACTCTCCGTAACGTGTGCATCAAGACAGAGCCCGTGAAGACGGAGGGCTTCAACAGCGTGGATGAGCAGAGAGTACTGGACTTGAAATACAGCGCGCCGCTGCAGCCGCATCAGAGAAGTCTTAGTATGAACAGGATATCAGTGCTAACAGATGGCACGTCCCTCTCTCTAGCAAGACGGCCCTCCTCTCCGACCAGCAGCGCCAAGTCCCTCGCACTCAGTGACCAGGGTTCCAATCACATGCCACACACCGGACTGGATCAAGTACAGAATCTGACTATCAAGAAAGAAACGCAGTTATCtgAATTAAAATGCGAGCAATCAGTGGGTATGGATAAGCTGATAGGTGCGTTACACGgctccccactgctgggaagaCTGCCACGCGTGCAGTCCAGTGCCAGCACGGACTCTGCAGTGCACTCCATGTATACACACAGTGTATACAGCAGTCCATCGGCGAGTCCTCGAGCGTCCAGACATTACACACCGTCCTTATCTCGTAACAACAGCGACGCCTCTCATTCCTCGTGCTACTCGTACAGCTCAGAGTTCTCACCCACGCATTCGCCAGTACAGGGTCGTCACCCGCACGTGTTGTACCGCGAGGCGGCCGCAGCCTACGAGGGCGCGCACGATGACGAACAGGACGCACCCGAGGACAGGCTGCATCATCATCAGGGGATCAGTAGACAACAGCTTATTAACAGTCCATGTCCAATCTGCGGCGACAAAATCAGCGGCTTCCACTACGGCATCTTCtcctgtgaatcatgcaagggTTTCTTCAAGCGCACTGTGCAGAACCGCAAGAACTACATGTGTCTCCGGGGCGGGAACTGTCCCGTCACTGTCACTACTAGGAAGAAGTGTCCCGCCTGCCGGTTTGACAAGTGTCTTGGATGCGGGATGAAGCTTGAagCTATCAGAGAGGACCGCACTAGAGGAGGTCGCTCCACCTACCAGTGTTCCTACACTCTGTCGGGCGCGGCGTCTACCGGCTCTCTCCTGTCTGCGCACGCGCCGACCACGCTACGACACGCCTCCAGCCTCACTTGTGTCAATGGTCCCGGGTCATATAGCAGCAGAGGGGAATCCAGTAACAGTCAAGTTACCCCAGATATACCGCCGTTATTGCAGGAAATAATGGACGTGGAACATCTGTGGCAGTACAACGAGTCTGAACTGAGTCGCCTCGGCAAGTCCACGGGCGGCAGTCCCTCCGCCAACCCGCTGCTGGCCGCCAGCGGGATCACGGCACACAACTCCAGCCCCGACTTCCTCGCTGACTTGTGCAATATCGCTGATCATAGGCTTTATAAGATCGTCAAGTGGTGCAAGAGTTTGCCGCTCTTTAAGAATATTTCGATCGACGACCAGATCTGCCTCCTGATCAACAGCTGGTGTGAGCTGCTAGTACTTTCATGTTGCTACCGCGGAGTGAGCACTCCGGGCGAGGTGCGCGTTGGAGGAGGGAGAGGAATCACGCTGCATCAGAGTGCTAAACTGGGTCTGACGCCGTGTATCGAGCGCATGTTGAGCTTCACGGACCACTTGAGGCGGCTGCGTGTGGACCGGTACGAGTACGTCGCGCTCAAAGTTATCGTACTACTCACTTCAGACGCCCCAGATCTACGTGAAGTGGAGAAAGTACGAGCCTCCCAGGAGAAAGCGTTAGCAGCACTACAAGCATACATCGCGACCCACTCCCCGGGCACTCCAGCCAAGTTCGGGGAACTACTGCTGCGTATACCTGAATTACAGAGGACTTGCCAGTTCTTCATGCAAGTCGGCAAAGAAATGCTGAACCCAGCTAACAAAAGTAAAGATGGCGACGGACCAAGCTTCAACCTACTCATGGAACTGCTGCGCGGAGACCATTGA
Protein Sequence: MSSEGDAVKVEGGHVSVTTISMSGPETSNGQFSYSSSGVRISVSSVPHDEDSTDAEISKIDFSQHQYEVNMRNKKKRSLSGAQELASNERERPMSWEGELSDSEMVIDTSVNNDETNSSLDLQSSRDSIDTLRNVCIKTEPVKTEGFNSVDEQRVLDLKYSAPLQPHQRSLSMNRISVLTDGTSLSLARRPSSPTSSAKSLALSDQGSNHMPHTGLDQVQNLTIKKETQLSELKCEQSVGMDKLIGALHGSPLLGRLPRVQSSASTDSAVHSMYTHSVYSSPSASPRASRHYTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQGRHPHVLYREAAAAYEGAHDDEQDAPEDRLHHHQGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGGNCPVTVTTRKKCPACRFDKCLGCGMKLEAIREDRTRGGRSTYQCSYTLSGAASTGSLLSAHAPTTLRHASSLTCVNGPGSYSSRGESSNSQVTPDIPPLLQEIMDVEHLWQYNESELSRLGKSTGGSPSANPLLAASGITAHNSSPDFLADLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLVLSCCYRGVSTPGEVRVGGGRGITLHQSAKLGLTPCIERMLSFTDHLRRLRVDRYEYVALKVIVLLTSDAPDLREVEKVRASQEKALAALQAYIATHSPGTPAKFGELLLRIPELQRTCQFFMQVGKEMLNPANKSKDGDGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00042698;
90% Identity: iTF_01076559;
80% Identity: iTF_00043674;